The Max Delbrück Center for Molecular Medicine carries out basic biomedical research. We try to understand the causes of diseases at the molecular level, in order to better diagnose, treat and prevent them. Our aim is to transfer our findings as quickly as possible into practical applications.


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Research Highlights

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Feeling an invisible world

Our sense of vibration is so precise that it detects structures too small to be seen with the most powerful microscopes. Kate Poole and Gary Lewin's lab have now developed a method to stimulate neurons at this tiny scale and measure the electrochemical signals they generate. In the process they discovered a protein that increases the sensitivity of neurons 10-fold. The paper appeared in a recent edition of Nature Communications.

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A broken tool and broken hearts

Norbert Hübner's lab, collaborating with many other groups at the MDC, has discovered how a protein called RBM20 binds to RNA molecules and influences the way they are spliced to produce different versions of proteins. The work helps explain how mutations in RBM20 and other molecules lead to the development of dilated cardiomyopathy, a severe cardiovascular disease. The work appears in a recent issue of the Journal of Clinical Investigation.

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