The MDC Mission

The Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) carries out basic biomedical research with the aim of understanding the molecular basis of health and disease, and translating these findings as quickly as possible into clinical application. The research involves the diagnosis and treatment of diseases, as well as their prevention.

Research Highlights

New brick in PKA Legoland adds complexity to a picture we thought we knew well

Protein Kinase A (PKA) is a protein that enjoys enough fame to be sketched by young biochemists listening to lectures about how it is regulated. The fundamental kinase is present throughout the body with a role in countless processes. It's easy to think PKA is so well studied that we know everything about it, but scientists at the MDC have found a new layer of PKA regulation which was published this week in Nature Communications.


Disturbance wanted – Newly characterized protein interaction may help in search for new cancer-fighting drugs

Some anticancer agents intend to disturb the function of the p97 protein complex, which is essential for survival of cancer cells. A team of researchers of the MDC has now found a way to break up the p97 complex into its subunits.


Further research highlights


How to make a motor neuron

Scientists have uncovered details of the cellular mechanisms that control the direct programming of stem cells into motor neurons. The scientists analyzed changes that occur in the cells over the course of the reprogramming process.


Martin Lohse awarded Poulsson medal

Pharmacologist Prof. Martin Lohse, who is Scientific Director of the MDC received the Poulsson Medal by The Norwegian Society of Pharmacology and Toxicology (NSFT). The scientific award honors Prof. Lohse's scientific contribution to the field and his efforts in teaching.


Erik McShane awarded MDC PhD Prize of 2016

Some proteins behave in an unusual way: the older they become, the more stable they are. This is what Erik McShane found out, this year's winner of the annual PhD Prize Award.


Further news on MDC Insights