The Max Delbrück Center for Molecular Medicine carries out basic biomedical research. We try to understand the causes of diseases at the molecular level, in order to better diagnose, treat and prevent them. Our aim is to transfer our findings as quickly as possible into practical applications.


campus03

Research Highlights

highlight

Unwinding defective messenger RNAs

Evolution has produced quality control systems that permit our cells to detect and destroy defective messenger RNAs before they go on to produce faulty proteins. Markus Landthaler's group has now discovered how a protein called an RNA helicase helps process RNAs so that they can be destroyed or recycled. The work appeared in the May 22 edition of Molecular Cell.

more

highlight

How to reinsulate a stripped nerve

The efficient transmission of electrical impulses in our nervous system requires that cells wrap themselves around the axons of neurons and act as insulators. This process of myelination slows down during aging and is disrupted in a number of serious diseases. Carmen Birchmeier's lab has now collaborated with other groups at the MDC to reveal a signaling system that can be stimulated to increase the production of myelin throughout an animal's lifetime. The work appears in a recent issue of Genes and Development.

more