The Max Delbrück Center for Molecular Medicine carries out basic biomedical research. We try to understand the causes of diseases at the molecular level, in order to better diagnose, treat and prevent them. Our aim is to transfer our findings as quickly as possible into practical applications.


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Research Highlights

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The search for the VRAC

A few years ago Thomas Jentsch thought the time had come to take on a question that had teased biologists for decades: How do cells reduce their volume? Four years later, a collaboration between his group and the Screening Unit has finally produced an answer. This feature-length highlight recounts how the group discovered the Volume-regulated anion channel (VRAC), as reported in the May 9 issue of Science.

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Unwinding defective messenger RNAs

Evolution has produced quality control systems that permit our cells to detect and destroy defective messenger RNAs before they go on to produce faulty proteins. Markus Landthaler's group has now discovered how a protein called an RNA helicase helps process RNAs so that they can be destroyed or recycled. The work appeared in the May 22 edition of Molecular Cell.

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