The Max Delbrück Center for Molecular Medicine carries out basic biomedical research. We try to understand the causes of diseases at the molecular level, in order to better diagnose, treat and prevent them. Our aim is to transfer our findings as quickly as possible into practical applications.


campus03

Research Highlights

highlight

A broken tool and broken hearts

Norbert Hübner's lab, collaborating with many other groups at the MDC, has discovered how a protein called RBM20 binds to RNA molecules and influences the way they are spliced to produce different versions of proteins. The work helps explain how mutations in RBM20 and other molecules lead to the development of dilated cardiomyopathy, a severe cardiovascular disease. The work appears in a recent issue of the Journal of Clinical Investigation.

more

highlight

The search for the VRAC

A few years ago Thomas Jentsch thought the time had come to take on a question that had teased biologists for decades: How do cells reduce their volume? Four years later, a collaboration between his group and the Screening Unit has finally produced an answer. This feature-length highlight recounts how the group discovered the Volume-regulated anion channel (VRAC), as reported in the May 9 issue of Science.

more