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Brain renin-angiotensin system: does it exist?
Hypertension 69 (6): 1136-1144 (2017-06)

Leonhardt J.; Villela D.C.; Teichmann A.; Muenter L.-M.; Mayer M.C.; Mardahl M.; Kirsch S.; Namsolleck P.; Lucht K.; Benz V.; Alenina N.; Daniell N.; Horiuchi M.; Iwai M.; Multhaup G.; Schuelein R.; Bader M.; Santos R.A.; Unger T.; Steckelings U.M.
Evidence for heterodimerization and functional interaction of the angiotensin Type 2 receptor and the receptor MAS
Hypertension 69 (6): 1128-1135 (2017-06)

Bader M.
Of mice and renin
Hypertension : (2017-05-22)

Jaerve A.; Muehlstedt S.; Qadri F.; Nickl B.; Schulz H.; Huebner N.; Oezcelik C.; Bader M.
Adverse left ventricular remodeling by glycoprotein nonmetastatic melanoma protein B in myocardial infarction
FASEB Journal 31 (2): 556-568 (2017-02)

Reichhart N.; Crespo-Garcia S.; Haase N.; Golic M.; Skosyrski S.; Ruebsam A.; Herrspiegel C.; Kociok N.; Alenina N.; Bader M.; Dechend R.; Strauss O.; Joussen A.M.
The TetO rat as a new translational model for type 2 diabetic retinopathy by inducible insulin receptor knockdown
Diabetologia 60 (1): 202-211 (2017-01)


Hadar R.; Edemann-Callesen H.; Reinel C.; Wieske F.; Voget M.; Popova E.; Sohr R.; Avchalumov Y.; Priller J.; van Riesen C.; Puls I.; Bader M.; Winter C.
Rats overexpressing the dopamine transporter display behavioral and neurobiological abnormalities with relevance to repetitive disorders
Scientific Reports 6: 39145 (2016-12-15)

Hammer A.; Yang G.; Friedrich J.; Kovacs A.; Lee D.H.; Grave K.; Joerg S.; Alenina N.; Grosch J.; Winkler J.; Gold R.; Bader M.; Manzel A.; Rump L.C.; Mueller D.N.; Linker R.A.; Stegbauer J.
Role of the receptor Mas in macrophage-mediated inflammation in vivo
Proceedings of the National Academy of Sciences of the United States of America 113 (49): 14109-14114 (2016-12-06)

Buttgereit J.; Shanks J.; Li D.; Hao G.; Athwal A.; Langenickel T.H.; Wright H.; da Costa Goncalves A.C.; Monti J.; Plehm R.; Popova E.; Qadri F.; Lapidus I.; Ryan B.; Ozcelik C.; Paterson D.J.; Bader M.; Herring N.
C-type natriuretic peptide and NPR-B signalling inhibits cardiac sympathetic neurotransmission and autonomic function
Cardiovascular Research 112 (3): 637-644 (2016-12)

Choo H.J.; Cutler A.; Rother F.; Bader M.; Pavlath G.K.
Karyopherin alpha 1 regulates satellite cell proliferation and survival by modulating nuclear import
Stem Cells 34 (11): 2784-2797 (2016-11)

Domenig O.; Manzel A.; Grobe N.; Koenigshausen E.; Kaltenecker C.C.; Kovarik J.J.; Stegbauer J.; Gurley S.B.; van Oyen D.; Antlanger M.; Bader M.; Motta-Santos D.; Santos R.A.; Elased K.M.; Saeemann M.D.; Linker R.A.; Poglitsch M.
Neprilysin is a mediator of alternative renin-angiotensin-system activation in the murine and human kidney
Scientific Reports 6: 33678 (2016-09-21)

Batalha V.L.; Ferreira D.G.; Coelho J.E.; Valadas J.S.; Gomes R.; Temido-Ferreira M.; Shmidt T.; Baqi Y.; Buee L.; Mueller C.E.; Hamdane M.; Outeiro T.F.; Bader M.; Meijsing S.H.; Sadri-Vakili G.; Blum D.; Lopes L.V.
The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function
Scientific Reports 6: 31493 (2016-08-11)

Schloss M.J.; Horckmans M.; Nitz K.; Duchene J.; Drechsler M.; Bidzhekov K.; Scheiermann C.; Weber C.; Soehnlein O.; Steffens S.
The time-of-day of myocardial infarction onset affects healing through oscillations in cardiac neutrophil recruitment
EMBO Molecular Medicine 8 (8): 937-948 (2016-08-01)

Winkler M.; Schuchard J.; Stoelting I.; Vogt F.M.; Barkhausen J.; Thorns C.; Bader M.; Raasch W.
The brain renin-angiotensin system plays a crucial role in regulating body weight in diet-induced rat obesity
British Journal of Pharmacology 173 (10): 1602-1617 (2016-05)

Reimann H.M.; Hentschel J.; Marek J.; Huelnhagen T.; Todiras M.; Kox S.; Waiczies S.; Hodge R.; Bader M.; Pohlmann A.; Niendorf T.
Normothermic mouse functional MRI of acute focal thermostimulation for probing nociception
Scientific Reports 6: 17230 (2016-01-29)

Silva C.R.; Oliveira S.M.; Hoffmeister C.; Funck V.; Guerra G.P.; Trevisan G.; Tonello R.; Rossato M.F.; Pesquero J.B.; Bader M.; Oliveira M.S.; McDougall J.J.; Ferreira J.
The role of kinin B1 receptor and the effect of angiotensin I-converting enzyme inhibition on acute gout attacks in rodents
Annals of the Rheumatic Diseases 75 (1): 260-268 (2016-01)


Gabriel G.; Feldmann F.; Reimer R.; Thiele S.; Fischer M.; Hartmann E.; Bader M.; Ebihara H.; Hoenen T.; Feldmann H.
Importin-{alpha}7 is involved in the formation of Ebola virus inclusion bodies but is not essential for pathogenicity in mice
Journal of Infectious Diseases 212 (Suppl 2): S316-S321 (2015-10-01)

Schuchard J.; Winkler M.; Stoelting I.; Schuster F.; Vogt F.M.; Barkhausen J.; Thorns C.; Santos R.A.; Bader M.; Raasch W.
Lack of weight gain after angiotensin AT1 receptor blockade in diet-induced obesity is partly mediated by an angiotensin-(1-7)/Mas-dependent pathway
British Journal of Pharmacology 172 (15): 3764-3778 (2015-08)

Maass P.G.; Aydin A.; Luft F.C.; Schaechterle C.; Weise A.; Stricker S.; Lindschau C.; Vaegler M.; Qadri F.; Toka H.R.; Schulz H.; Krawitz P.M.; Parkhomchuk D.; Hecht J.; Hollfinger I.; Wefeld-Neuenfeld Y.; Bartels-Klein E.; Muehl A.; Kann M.; Schuster H.; Chitayat D.; Bialer M.G.; Wienker T.F.; Ott J.; Rittscher K.; Liehr T.; Jordan J.; Plessis G.; Tank J.; Mai K.; Naraghi R.; Hodge R.; Hopp M.; Hattenbach L.O.; Busjahn A.; Rauch A.; Vandeput F.; Gong M.; Rueschendorf F.; Huebner N.; Haller H.; Mundlos S.; Bilginturan N.; Movsesian M.A.; Klussmann E.; Toka O.; Baehring S.
PDE3A mutations cause autosomal dominant hypertension with brachydactyly
Nature Genetics 47 (6): 647-653 (2015-06)

Walentin K.; Hinze C.; Werth M.; Haase N.; Varma S.; Morell R.; Aue A.; Poetschke E.; Warburton D.; Qiu A.; Barasch J.; Purfuerst B.; Dieterich C.; Popova E.; Bader M.; Dechend R.; Staff A.C.; Yurtdas Z.Y.; Kilic E.; Schmidt-Ott K.M.
A Grhl2-dependent gene network controls trophoblast branching morphogenesis
Development 142 (6): 1125-1136 (2015-03-15)

Andersen L.B.; Przybyl L.; Haase N.; von Versen-Hoeynck F.; Qadri F.; Jorgensen J.S.; Sorensen G.L.; Fruekilde P.; Poglitsch M.; Szijarto I.; Gollasch M.; Peters J.; Muller D.N.; Christesen H.T.; Dechend R.
Vitamin D depletion aggravates hypertension and target-organ damage
Journal of the American Heart Association 4 (2): e001417 (2015-02)

Villela D.; Leonhardt J.; Patel N.; Joseph J.; Kirsch S.; Hallberg A.; Unger T.; Bader M.; Santos R.A.; Sumners C.; Steckelings U.M.
Angiotensin type 2 receptor (AT2R) and receptor Mas: a complex liaison
Clinical Science 128 (4): 227-234 (2015-02-01)


Cui Y.; Niziolek P.J.; MacDonald B.T.; Alenina N.; Matthes S.; Jacobsen C.M.; Conlon R.A.; Brommage R.; Powell D.R.; He X.; Bader M.; Williams B.O.; Warman M.L.; Robling A.G.
Reply to Lrp5 regulation of bone mass and gut serotonin synthesis
Nature Medicine 20 (11): 1229-1230 (2014-11-06)

Marko L.; Henke N.; Park J.K.; Spallek B.; Qadri F.; Balogh A.; Apel I.J.; Oravecz-Wilson K.I.; Choi M.; Przybyl L.; Binger K.J.; Haase N.; Wilck N.; Heuser A.; Fokuhl V.; Ruland J.; Lucas P.C.; McAllister-Lucas L.M.; Luft F.C.; Dechend R.; Mueller D.N.
Bcl10 mediates angiotensin II-induced cardiac damage and electrical remodeling
Hypertension 64 (5): 1032-1039 (2014-11)

Mosienko V.; Matthes S.; Hirth N.; Beis D.; Flinders M.; Bader M.; Hansson A.C.; Alenina N.
Adaptive changes in serotonin metabolism preserve normal behavior in mice with reduced TPH2 activity
Neuropharmacology 85C: 73-80 (2014-10)

Bader M.; Alenina N.; Andrade-Navarro M.A.; Santos R.A.
Mas and its related G protein-coupled receptors, Mrgprs
Pharmacological Reviews 66 (4): 1080-1105 (2014-10)

Pulgar V.M.; Yamaleyeva L.M.; Varagic J.; McGee C.M.; Bader M.; Dechend R.; Howlett A.C.; Brosnihan K.B.
Increased angiotensin II contraction of the uterine artery at early gestation in a transgenic model of hypertensive pregnancy is reduced by inhibition of endocannabinoid hydrolysis
Hypertension 64 (3): 619-625 (2014-09)

Kuppusamy M.; Caroccia B.; Stindl J.; Bandulik S.; Lenzini L.; Gioco F.; Fishman V.; Zanotti G.; Gomez-Sanchez C.; Bader M.; Warth R.; Rossi G.P.
A novel KCNJ5-insT149 somatic mutation close to, but outside, the selectivity filter causes resistant hypertension by loss of selectivity for potassium
Journal of Clinical Endocrinology and Metabolism 99 (9): E1765-E1773 (2014-09)

Pena Silva R.A.; Kung D.K.; Mitchell I.J.; Alenina N.; Bader M.; Santos R.A.S.; Faraci F.M.; Heistad D.D.; Hasan D.M.
Angiotensin 1-7 reduces mortality and rupture of intracranial aneurysms in mice
Hypertension 64 (2): 362-368 (2014-08)

Schleifenbaum J.; Kassmann M.; Szijarto I.A.; Hercule H.C.; Tano J.Y.; Weinert S.; Heidenreich M.; Pathan A.R.; Anistan Y.M.; Alenina N.; Rusch N.J.; Bader M.; Jentsch T.J.; Gollasch M.
Stretch-activation of angiotensin II type 1a receptors contributes to the myogenic response of mouse mesenteric and renal arteries
Circulation Research 115 (2): 263-272 (2014-07-07)

Jastrzebska J.; Nowak E.; Smaga I.; Bystrowska B.; Frankowska M.; Bader M.; Filip M.; Fuxe K.
Adenosine (A)2A receptor modulation of nicotine-induced locomotor sensitization: a pharmacological and transgenic approach
Neuropharmacology 81: 318-326 (2014-06)

Huegel S.; Depping R.; Dittmar G.; Rother F.; Cabot R.; Sury M.D.; Hartmann E.; Bader M.
Identification of importin alpha 7 specific transport cargoes using a proteomic screening approach
Molecular & Cellular Proteomics 13 (5): 1286-1298 (2014-05-01)

Rousselle A.; Sihn G.; Rotteveel M.; Bader M.
(Pro)renin receptor and V-ATPase: from Drosophila to humans
Clinical Science 126 (8): 529-536 (2014-04-01)

Lenzini L.; Caroccia B.; Campos A.G.; Fassina A.; Belloni A.S.; Seccia T.M.; Kuppusamy M.; Ferraro S.; Skander G.; Bader M.; Rainey W.E.; Rossi G.P.
Lower expression of the Twik-related acid-sensitive K(+) channel 2 (TASK-2) gene is a hallmark of aldosterone producing adenoma causing human primary aldosteronism
Journal of Clinical Endocrinology and Metabolism 99 (4): E674-E682 (2014-04)

Lee G.S.; Simpson C.; Sun B.H.; Yao C.; Foer D.; Sullivan B.; Matthes S.; Alenina N.; Belsky J.; Bader M.; Insogna K.L.
Measurement of plasma, serum, and platelet serotonin in individuals with high bone mass and mutations in LRP5
Journal of Bone and Mineral Research 29 (4): 976-981 (2014-04)

Santos S.H.S.; Giani J.F.; Burghi V.; Miquet J.G.; Qadri F.; Braga J.F.; Todiras M.; Kotnik K.; Alenina N.; Dominici F.P.; Santos R.A.S.; Bader M.
Oral administration of angiotensin-(1-7) ameliorates type 2 diabetes in rats
Journal of Molecular Medicine 92 (3): 255-265 (2014-03)

Acuna M.J.; Pessina P.; Olguin H.; Cabrera D.; Vio C.P.; Bader M.; Munoz-Canoves P.; Santos R.A.; Cabello-Verrugio C.; Brandan E.
Restoration of muscle strength in dystrophic muscle by Angiotensin-1-7 through inhibition of TGF-{beta} signaling
Human Molecular Genetics 23 (5): 1237-1249 (2014-03-01)


Klempin F.; Beis D.; Mosienko V.; Kempermann G.; Bader M.; Alenina N.
Serotonin is required for exercise-induced adult hippocampal neurogenesis
Journal of Neuroscience 33 (19): 8270-8275 (2013-05-08)

Lautner R.Q.; Villela D.C.; Fraga-Silva R.A.; Silva N.C.; Verano-Braga T.; Costa-Fraga F.; Jankowski J.; Jankowski V.; De Sousa F.B.; Alzamora A.C.; Soares E.R.; Barbosa C.M.; Kjeldsen F.; Oliveira A.C.; Braga J.F.; Savergnini S.Q.; Etelvino G.M.; Bastos Peluso A.A.; Passos-Silva D.G.; Ferreira A.J.; Alves F.; Martins A.S.; Raizada M.K.; Paula R.D.; Motta-Santos D.; Klempin F.; Pimenta A.M.C.; Alenina N.; Sinisterra R.D.M.; Bader M.; Campagnole-Santos M.J.; Santos R.A.S.
Discovery and characterization of alamandine, a novel component of the renin-angiotensin system
Circulation Research 112 (8): 1104-1111 (2013-04-12)

Cristofaro B.; Shi Y.; Faria M.; Suchting S.; Leroyer A.S.; Trindade A.; Duarte A.; Zovein A.C.; Iruela-Arispe M.L.; Nih L.R.; Kubis N.; Henrion D.; Loufrani L.; Todiras M.; Schleifenbaum J.; Gollasch M.; Zhuang Z.W.; Simons M.; Eichmann A.; le Noble F.
Dll4-Notch signaling determines the formation of native arterial collateral networks and arterial function in mouse ischemia models
Development 140 (8): 1720-1729 (2013-04)

Katter K.; Geurts A.M.; Hoffmann O.; Mates L.; Landa V.; Hiripi L.; Moreno C.; Lazar J.; Bashir S.; Zidek V.; Popova E.; Jerchow B.; Becker K.; Devaraj A.; Walter I.; Grzybowksi M.; Corbett M.; Filho A.R.; Hodges M.R.; Bader M.; Ivics Z.; Jacob H.J.; Pravenec M.; Bosze Z.; Ruelicke T.; Izsvak Z.
Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits
FASEB Journal 27 (3): 930-941 (2013-03)

Rousselle A.; Qadri F.; Leukel L.; Yilmaz R.; Fontaine J.F.; Sihn G.; Bader M.; Ahluwalia A.; Duchene J.
CXCL5 limits macrophage foam cell formation in atherosclerosis
Journal of Clinical Investigation 123 (3): 1343-1347 (2013-03-01)

Duerschmied D.; Suidan G.L.; Demers M.; Herr N.; Carbo C.; Brill A.; Cifuni S.M.; Mauler M.; Cicko S.; Bader M.; Idzko M.; Bode C.; Wagner D.D.
Platelet serotonin promotes the recruitment of neutrophils to sites of acute inflammation in mice
Blood 121 (6): 1008-1015 (2013-02-07)

Kraenkel N.; Kuschnerus K.; Mueller M.; Speer T.; Mocharla P.; Madeddu P.; Bader M.; Luescher T.F.; Landmesser U.
Novel insights into the critical role of bradykinin and the kinin B2 receptor for vascular recruitment of circulating endothelial repair-promoting mononuclear cell subsets: alterations in patients with coronary disease
Circulation 127 (5): 594-603 (2013-02-05)

Machado de Almeida P.W.; de Freitas Lima R.; de Morais Gomes E.R.; Rocha-Resende C.; Roman-Campos D.; Gondim A.N.S.; Gavioli M.; Lara A.; Parreira A.; de Azevedo Nunes S.L.; Alves M.N.M.; Lauton Santos S.; Alenina N.; Bader M.; Ribeiro Resende R.; dos Santos Cruz J.; Souza dos Santos R.A.; Guatimosim S.
Functional cross-talk between aldosterone and angiotensin-(1-7) in ventricular myocytes
Hypertension 61 (2): 425-430 (2013-02)

Chuykin I.; Schulz H.; Guan K.; Bader M.
Activation of the PTHRP/adenylate cyclase pathway promotes differentiation of rat XEN cells into parietal endoderm, whereas Wnt/beta-catenin signaling promotes differentiation into visceral endoderm
Journal of Cell Science 126 (Pt 1): 128-138 (2013-01-01)


Chan M.V.; Bubb K.J.; Noyce A.; Villar I.C.; Duchene J.; Hobbs A.J.; Scotland R.S.; Ahluwalia A.
Distinct endothelial pathways underlie sexual dimorphism in vascular auto-regulation
British Journal of Pharmacology 167 (4): 805-817 (2012-10)

Albert-Weissenberger C.; Stetter C.; Meuth S.G.; Goebel K.; Bader M.; Siren A.L.; Kleinschnitz C.
Blocking of bradykinin receptor B1 protects from focal closed head injury in mice by reducing axonal damage and astroglia activation
Journal of Cerebral Blood Flow and Metabolism 32 (9): 1747-1756 (2012-09)

Cayla C.; Labuz D.; Machelska H.; Bader M.; Schaefer M.; Stein C.
Impaired nociception and peripheral opioid antinociception in mice lacking both kinin b1 and b2 receptors
Anesthesiology 116 (2): 448-457 (2012-02)

Ben-Yaakov K.; Dagan S.Y.; Segal-Ruder Y.; Shalem O.; Vuppalanchi D.; Willis D.E.; Yudin D.; Rishal I.; Rother F.; Bader M.; Blesch A.; Pilpel Y.; Twiss J.L.; Fainzilber M.
Axonal transcription factors signal retrogradely in lesioned peripheral nerve
EMBO Journal 31 (6): 1350-1363 (2012-01-13)


Riediger F.; Quack I.; Qadri F.; Hartleben B.; Park J.K.; Potthoff S.A.; Sohn D.; Sihn G.; Rousselle A.; Fokuhl V.; Maschke U.; Purfuerst B.; Schneider W.; Rump L.C.; Luft F.C.; Dechend R.; Bader M.; Huber T.B.; Nguyen G.; Mueller D.N.
Prorenin receptor is essential for podocyte autophagy and survival
Journal of the American Society of Nephrology 22 (12): 2193-2202 (2011-12)

Maurer M.; Bader M.; Bas M.; Bossi F.; Cicardi M.; Cugno M.; Howarth P.; Kaplan A.; Kojda G.; Leeb-Lundberg F.; Loetvall J.; Magerl M.
New topics in bradykinin research
Allergy 66 (11): 1397-1406 (2011-11)

Balkaya M.; Prinz V.; Custodis F.; Gertz K.; Kronenberg G.; Kroeber J.; Fink K.; Plehm R.; Gass P.; Laufs U.; Endres M.
Stress worsens endothelial function and ischemic stroke via glucocorticoids
Stroke 42 (11): 3258-3264 (2011-11)

Jankowski V.; Toelle M.; Santos R.A.; Guenthner T.; Krause E.; Beyermann M.; Welker P.; Bader M.; Pinheiro S.V.B.; Sampaio W.O.; Lautner R.; Kretschmer A.; van der Giet M.; Zidek W.; Jankowski J.
Angioprotectin: an angiotensin II-like peptide causing vasodilatory effects
FASEB Journal 25 (9): 2987-2995 (2011-09)

Hillmeister P.; Gatzke N.; Duelsner A.; Bader M.; Schadock I.; Hoefer I.; Hamann I.; Infante-Duarte C.; Jung G.; Troidl K.; Urban D.; Stawowy P.; Frentsch M.; Li M.; Nagorka S.; Wang H.; Shi Y.; Le Noble F.; Buschmann I.
Arteriogenesis is modulated on bradykinin receptor signaling
Circulation Research 109 (5): 524-533 (2011-08-19)

Cui Y.; Niziolek P.J.; Macdonald B.T.; Zylstra C.R.; Alenina N.; Robinson D.R.; Zhong Z.; Matthes S.; Jacobsen C.M.; Conlon R.A.; Brommage R.; Liu Q.; Mseeh F.; Powell D.R.; Yang Q.M.; Zambrowicz B.; Gerrits H.; Gossen J.A.; He X.; Bader M.; Williams B.O.; Warman M.L.; Robling A.G.
Lrp5 functions in bone to regulate bone mass
Nature Medicine 17 (6): 684-691 (2011-06)

Dees C.; Akhmetshina A.; Zerr P.; Reich N.; Palumbo K.; Horn A.; Juengel A.; Beyer C.; Kroenke G.; Zwerina J.; Reiter R.; Alenina N.; Maroteaux L.; Gay S.; Schett G.; Distler O.; Distler J.H.
Platelet-derived serotonin links vascular disease and tissue fibrosis
Journal of Experimental Medicine 208 (5): 961-972 (2011-05-09)

Guimaraes P.B.; Alvarenga E.C.; Siqueira P.D.; Paredes-Gamero E.J.; Sabatini R.A.; Morais R.L.; Reis R.I.; Santos E.L.; Teixeira L.G.; Casarini D.E.; Martin R.P.; Shimuta S.I.; Carmona A.K.; Nakaie C.R.; Jasiulionis M.G.; Ferreira A.T.; Pesquero J.L.; Oliveira S.M.; Bader M.; Costa-Neto C.M.; Pesquero J.B.
Angiotensin II binding to angiotensin I-converting enzyme triggers calcium signaling
Hypertension 57 (5): 965-972 (2011-05)

Hinrichs S.; Heger J.; Schreckenberg R.; Wenzel S.; Euler G.; Arens C.; Bader M.; Rosenkranz S.; Caglayan E.; Schlueter K.D.
Controlling cardiomyocyte length: The role of renin and PPAR-{gamma}
Cardiovascular Research 89 (2): 344-352 (2011-02-01)

Ghadge S.; Muehlstedt S.; Oezcelik C.; Bader M.
SDF-1alpha as a therapeutic stem cell homing factor in myocardial infarction
Pharmacology & Therapeutics 129 (1): 97-108 (2011-01)

Gabriel G.; Klingel K.; Otte A.; Thiele S.; Hudjetz B.; Arman-Kalcek G.; Sauter M.; Shmidt T.; Rother F.; Baumgarte S.; Keiner B.; Hartmann E.; Bader M.; Brownlee G.G.; Fodor E.; Klenk H.D.
Differential use of importin-alpha isoforms governs cell tropism and host adaptation of influenza virus
Nature Communications 2 (1): 156 (2011-01)


Pohl M.; Kaminski H.; Castrop H.; Bader M.; Himmerkus N.; Bleich M.; Bachmann S.; Theilig F.
Intrarenal renin angiotensin system revisited: role of megalin-dependent endocytosis along the proximal nephron
Journal of Biological Chemistry 285 (53): 41935-41946 (2010-12-31)

Werth M.; Walentin K.; Aue A.; Schoenheit J.; Wuebken A.; Pode-Shakked N.; Vilianovitch L.; Erdmann B.; Dekel B.; Bader M.; Barasch J.; Rosenbauer F.; Luft F.C.; Schmidt-Ott K.M.
The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex
Development 137 (22): 3835-3845 (2010-11)

Silveira K.D.; Coelho F.M.; Vieira A.T.; Sachs D.; Barroso L.C.; Costa V.V.; Bretas T.L.B.; Bader M.; Sousa L.P.; Silva T.A.; Santos R.A.S.; Simoes E Silva A.C.; Teixeira M.M.
Anti-inflammatory effects of the activation of the angiotensin-(1-7) receptor, Mas, in experimental models of arthritis
Journal of Immunology 185 (9): 5569-5576 (2010-11-01)

Hilzendeger A.M.; Morais R.L.; Todiras M.; Plehm R.; da Costa Goncalves A.; Qadri F.; Carvalho Araujo R.; Gross V.; Nakaie C.R.; Casarini D.E.; Carmona A.K.; Bader M.; Pesquero J.B.
Leptin regulates ACE activity in mice
Journal of Molecular Medicine 88 (9): 899-907 (2010-09)

Sihn G.; Rousselle A.; Vilianovitch L.; Burckle C.; Bader M.
Physiology of the (pro)renin receptor: Wnt of change?
Kidney International 78 (3): 246-256 (2010-08)

Savergnini S.Q.; Beiman M.; Lautner R.Q.; de Paula-Carvalho V.; Allahdadi K.; Pessoa D.C.; Costa-Fraga F.P.; Fraga-Silva R.A.; Cojocaru G.; Cohen Y.; Bader M.; de Almeida A.P.; Rotman G.; Santos R.A.
Vascular relaxation, antihypertensive effect, and cardioprotection of a novel peptide agonist of the Mas receptor
Hypertension 56 (1): 112-120 (2010-07)

Reiche J.; Theilig F.; Rafiqi F.H.; Carlo A.S.; Militz D.; Mutig K.; Todiras M.; Christensen E.I.; Ellison D.H.; Bader M.; Nykjaer A.; Bachmann S.; Alessi D.; Willnow T.E.
SORLA/SORL1 functionally interacts with SPAK to control renal activation of Na+-K+-Cl- cotransporter 2
Molecular and Cellular Biology 30 (12): 3027-3037 (2010-06)

Santos S.H.; Felix Braga J.; Mario E.G.; Porto L.C.; Rodrigues-Machado M.D.; Murari A.; Botion L.M.; Alenina N.; Bader M.; Santos R.A.
Improved lipid and glucose metabolism in transgenic rats with increased circulating angiotensin-(1-7)
Arteriosclerosis Thrombosis and Vascular Biology 30 (5): 953-61 (2010-05)

Rompe F.; Artuc M.; Hallberg A.; Alterman M.; Stroeder K.; Thoene-Reineke C.; Reichenbach A.; Schacherl J.; Dahloef B.; Bader M.; Alenina N.; Schwaninger M.; Zuberbier T.; Funke-Kaiser H.; Schmidt C.; Schunck W.H.; Unger T.; Steckelings U.M.
Direct angiotensin II type 2 receptor stimulation acts anti-inflammatory through epoxyeicosatrienoic acid and inhibition of nuclear factor {kappa}B
Hypertension 55 (4): 924-931 (2010-04)

Hilzendeger A.M.; da Costa Goncalves A.C.; Plehm R.; Diedrich A.; Gross V.; Pesquero J.B.; Bader M.
Autonomic dysregulation in ob/ob mice is improved by inhibition of angiotensin-converting enzyme
Journal of Molecular Medicine 88 (4): 383-390 (2010-04)

Bader M.
Tissue renin-angiotensin-aldosterone systems: Targets for pharmacological therapy
Annual Review of Pharmacology and Toxicology 50: 439-65 (2010)

Gomes E.R.; Lara A.A.; Almeida P.W.; Guimaraes D.; Resende R.R.; Campagnole-Santos M.J.; Bader M.; Santos R.A.; Guatimosim S.
Angiotensin-(1-7) prevents cardiomyocyte pathological remodeling through a nitric oxide/guanosine 3',5'-cyclic monophosphate-dependent pathway
Hypertension 55 (1): 153-160 (2010-01)


Hanada R.; Leibbrandt A.; Hanada T.; Kitaoka S.; Furuyashiki T.; Fujihara H.; Trichereau J.; Paolino M.; Qadri F.; Plehm R.; Klaere S.; Komnenovic V.; Mimata H.; Yoshimatsu H.; Takahashi N.; von Haeseler A.; Bader M.; Kilic S.S.; Ueta Y.; Pifl C.; Narumiya S.; Penninger J.M.
Central control of fever and female body temperature by RANKL/RANK
Nature 462 (7272): 505-509 (2009-11-26)

Paulmann N.; Grohmann M.; Voigt J.P.; Bert B.; Vowinckel J.; Bader M.; Skelin M.; Jevsek M.; Fink H.; Rupnik M.; Walther D.J.
Intracellular serotonin modulates insulin secretion from pancreatic beta-cells by protein serotonylation
PLoS Biology 7 (10): e1000229 (2009-10-27)

Merino V.F.; Todiras M.; Mori M.A.; Sales V.M.; Fonseca R.G.; Saul V.; Tenner K.; Bader M.; Pesquero J.B.
Predisposition to atherosclerosis and aortic aneurysms in mice deficient in kinin B1 receptor and apolipoprotein E
Journal of Molecular Medicine 87 (10): 953-963 (2009-10)

Park J.K.; Theuer S.; Kirsch T.; Lindschau C.; Klinge U.; Heuser A.; Plehm R.; Todiras M.; Carmeliet P.; Haller H.; Luft F.C.; Mueller D.N.; Fiebeler A.
Growth arrest specific protein 6 participates in DOCA-induced target-organ damage
Hypertension 54 (2): 359-364 (2009-08)

Duerschmied D.; Canault M.; Lievens D.; Brill A.; Cifuni S.M.; Bader M.; Wagner D.D.
Serotonin stimulates platelet receptor shedding by tumor necrosis factor-alpha-converting enzyme (ADAM17)
Journal of Thrombosis and Haemostasis 7 (7): 1163-1171 (2009-07)

Schulze-Topphoff U.; Prat A.; Prozorovski T.; Siffrin V.; Paterka M.; Herz J.; Bendix I.; Ifergan I.; Schadock I.; Mori M.A.; Van Horssen J.; Schroeter F.; Smorodchenko A.; Han M.H.; Bader M.; Steinman L.; Aktas O.; Zipp F.
Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system
Nature Medicine 15 (7): 788-793 (2009-07)

Alenina N.; Kikic D.; Todiras M.; Mosienko V.; Qadri F.; Plehm R.; Boye P.; Vilianovitch L.; Sohr R.; Tenner K.; Hoertnagl H.; Bader M.
Growth retardation and altered autonomic control in mice lacking brain serotonin
Proceedings of the National Academy of Sciences of the United States of America 106 (25): 10332-10337 (2009-06-23)

Kahn R.; Hellmark T.; Leeb-Lundberg L.M.; Akbari N.; Todiras M.; Olofsson T.; Wieslander J.; Christensson A.; Westman K.; Bader M.; Mueller-Esterl W.; Karpman D.
Neutrophil-derived proteinase 3 induces kallikrein-independent release of a novel vasoactive kinin
Journal of Immunology 182 (12): 7906-7915 (2009-06-15)

Kvakan H.; Kleinewietfeld M.; Qadri F.; Park J.K.; Fischer R.; Schwarz I.; Rahn H.P.; Plehm R.; Wellner M.; Elitok S.; Gratze P.; Dechend R.; Luft F.C.; Mueller D.N.
Regulatory T cells ameliorate angiotensin II-induced cardiac damage
Circulation 119 (22): 2904-2912 (2009-06-09)

Pinheiro S.V.; Ferreira A.J.; Kitten G.T.; da Silveira K.D.; da Silva D.A.; Santos S.H.; Gava E.; Castro C.H.; Magalhaes J.A.; da Mota R.K.; Botelho-Santos G.A.; Bader M.; Alenina N.; Santos R.A.; Simoes E Silva A.C.
Genetic deletion of the angiotensin-(1-7) receptor Mas leads to glomerular hyperfiltration and microalbuminuria
Kidney International 75 (11): 1184-1193 (2009-06-01)

Westermann D.; Walther T.; Savvatis K.; Sobirey M.; Riad A.; Bader M.; Schultheiss H.P.; Tschoepe C.
Gene deletion of the kinin receptor B1 attenuates cardiac inflammation and fibrosis during the development of experimental diabetic cardiomyopathy
Diabetes 58 (6): 1373-1381 (2009-06)

Bader M.
Kallikrein-kinin system in neovascularization
Arteriosclerosis Thrombosis and Vascular Biology 29 (5): 617-619 (2009-05)

Kleinschnitz C.; Austinat M.; Stoll G.; Bader M.; Renne T.
Role of bradykinin and catecholamines in cerebral infarction and brain edema - Response
Stroke 40 (4): e104 (2009-04)

Ladhoff J.; Bader M.; Broesel S.; Effenberger E.; Westermann D.; Volk H.D.; Seifert M.
Low immunogenicity of endothelial derivatives from rat embryonic stem cell-like cells
Cell Research 19 (4): 507-518 (2009-04)

Gratze P.; Boschmann M.; Dechend R.; Qadri F.; Malchow J.; Graeske S.; Engeli S.; Janke J.; Springer J.; Contrepas A.; Plehm R.; Klaus S.; Nguyen G.; Luft F.C.; Mueller D.N.
Energy metabolism in human renin-gene transgenic rats. Does renin contribute to obesity?
Hypertension 53 (3): 516-523 (2009-03)

Wendt N.; Schulz A.; Qadri F.; Bolbrinker J.; Kossmehl P.; Winkler K.; Stoll M.; Vetter R.; Kreutz R.
Genetic analysis of salt-sensitive hypertension in Dahl rats reveals a link between cardiac fibrosis and high cholesterol
Cardiovascular Research 81 (3): 618-626 (2009-02-15)

da Costa Goncalves A.C.; Tank J.; Diedrich A.; Hilzendeger A.; Plehm R.; Bader M.; Luft F.C.; Jordan J.; Gross V.
Diabetic hypertensive leptin receptor-deficient db/db mice develop cardioregulatory autonomic dysfunction
Hypertension 53 (2): 387-392 (2009-02)

Hume A.N.; Buttgereit J.; Al-Awadhi A.M.; Al-Suwaidi S.S.; John A.; Bader M.; Seabra M.C.; Al-Gazali L.; Ali B.R.
Defective cellular trafficking of missense NPR-B mutants is the major mechanism underlying Acromesomelic Dysplasia type Maroteaux
Human Molecular Genetics 18 (2): 267-277 (2009-01-15)

Klein J.; Gonzalez J.; Duchene J.; Esposito L.; Pradere J.P.; Neau E.; Delage C.; Calise D.; Ahluwalia A.; Carayon P.; Pesquero J.B.; Bader M.; Schanstra J.P.; Bascands J.L.
Delayed blockade of the kinin B1 receptor reduces renal inflammation and fibrosis in obstructive nephropathy
FASEB Journal 23 (1): 134-142 (2009-01)

Austinat M.; Braeuninger S.; Pesquero J.B.; Brede M.; Bader M.; Stoll G.; Renne T.; Kleinschnitz C.
Blockade of bradykinin receptor B1 but not bradykinin receptor B2 provides protection from cerebral infarction and brain edema
Stroke 40 (1): 285-293 (2009-01)


Posch M.G.; Posch M.J.; Perrot A.; Dietz R.; Oezcelik C.
Variations in DSG2: V56M, V158G and V920G are not pathogenic for arrhythmogenic right ventricular dysplasia/cardiomyopathy
Nature Clinical Practice Cardiovascular Medicine 5 (12): E1 (2008-12)

Mercure C.; Yogi A.; Callera G.E.; Aranha A.B.; Bader M.; Ferreira A.J.; Santos R.A.; Walther T.; Touyz R.M.; Reudelhuber T.L.
Angiotensin(1-7) blunts hypertensive cardiac remodeling by a direct effect on the heart
Circulation Research 103 (11): 1319-1326 (2008-11-21)

Rentzsch B.; Todiras M.; Iliescu R.; Popova E.; Campos L.A.; Oliveira M.L.; Baltatu O.C.; Santos R.A.; Bader M.
Transgenic angiotensin-converting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function
Hypertension 52 (5): 967-973 (2008-11)

da Costa-Goncalves A.C.; Tank J.; Plehm R.; Diedrich A.; Todiras M.; Gollasch M.; Heuser A.; Wellner M.; Bader M.; Jordan J.; Luft F.C.; Gross V.
Role of the multidomain protein spinophilin in blood pressure and cardiac function regulation
Hypertension 52 (4): 702-707 (2008-10)

Xi L.; Das A.; Zhao Z.Q.; Merino V.F.; Bader M.; Kukreja R.C.
Loss of myocardial ischemic postconditioning in adenosine A1 and bradykinin B2 receptors gene knockout mice
Circulation 118 (14 Suppl): S32-S37 (2008-09-30)

Dias-Peixoto M.F.; Santos R.A.; Gomes E.R.; Alves M.N.; Almeida P.W.; Greco L.; Rosa M.; Fauler B.; Bader M.; Alenina N.; Guatimosim S.
Molecular mechanisms involved in the angiotensin-(1-7)/Mas signaling pathway in cardiomyocytes
Hypertension 52 (3): 542-548 (2008-09)

Lang P.A.; Contaldo C.; Georgiev P.; El-Badry A.M.; Recher M.; Kurrer M.; Cervantes-Barragan L.; Ludewig B.; Calzascia T.; Bolinger B.; Merkler D.; Odermatt B.; Bader M.; Graf R.; Clavien P.A.; Hegazy A.N.; Loehning M.; Harris N.L.; Ohashi P.S.; Hengartner H.; Zinkernagel R.M.; Lang K.S.
Aggravation of viral hepatitis by platelet-derived serotonin
Nature Medicine 14 (7): 756-761 (2008-07)

Nocito A.; Dahm F.; Jochum W.; Jang J.H.; Georgiev P.; Bader M.; Graf R.; Clavien P.A.
Serotonin regulates macrophage-mediated angiogenesis in a mouse model of colon cancer allografts
Cancer Research 68 (13): 5152-5158 (2008-07-01)

Dempsie Y.; Morecroft I.; Welsh D.J.; Macritchie N.A.; Herold N.; Loughlin L.; Nilsen M.; Peacock A.J.; Harmar A.; Bader M.; Maclean M.R.
Converging evidence in support of the serotonin hypothesis of dexfenfluramine-induced pulmonary hypertension with novel transgenic mice
Circulation 2008 (117): 2928-2937 (2008-06-03)

Mori M.A.; Araujo R.C.; Reis F.C.; Sgai D.G.; Fonseca R.G.; Barros C.C.; Merino V.F.; Passadore M.; Barbosa A.M.; Ferrari B.; Carayon P.; Castro C.H.; Shimuta S.I.; Luz J.; Bascands J.L.; Schanstra J.P.; Even P.C.; Oliveira S.M.; Bader M.; Pesquero J.B.
Kinin B1 receptor deficiency leads to leptin hypersensitivity and resistance to obesity
Diabetes 57 (6): 1491-1500 (2008-06)

Batenburg W.W.; de Bruin R.J.; van Gool J.M.; Mueller D.N.; Bader M.; Nguyen G.; Danser A.H.
Aliskiren-binding increases the half life of renin and prorenin in rat aortic vascular smooth muscle cells
Arteriosclerosis Thrombosis and Vascular Biology 28 (6): 1151-1157 (2008-06)

Gratze P.; Dechend R.; Stocker C.; Park J.K.; Feldt S.; Shagdarsuren E.; Wellner M.; Gueler F.; Rong S.; Gross V.; Obst M.; Plehm R.; Alenina N.; Zenclussen A.; Titze J.; Small K.; Yokota Y.; Zenke M.; Luft F.C.; Mueller D.N.
Novel role for inhibitor of differentiation 2 in the genesis of angiotensin II-induced hypertension
Circulation 117 (20): 2645-2656 (2008-05-20)

Posch M.G.; Berger F.; Perrot A.; Oezcelik C.
We need a detailed phenome in the phenomenon of genetics and congenital heart disease
Journal of Medical Genetics 45 (5): 320 (2008-05)

Duka A.; Kintsurashvili E.; Duka I.; Ona D.; Hopkins T.A.; Bader M.; Gavras I.; Gavras H.
Angiotensin-converting enzyme inhibition after experimental myocardial infarct: Role of the kinin B1 and B2 receptors
Hypertension 51 (5): 1352-1357 (2008-05)

Kleinschnitz C.; Austinat M.; Bader M.; Renne T.; Stoll G.
Deficiency of bradykinin receptor B2 is not detrimental in experimental stroke
Hypertension 51 (5): e41 (2008-05)

Andre E.; Gazzieri D.; Bardella E.; Ferreira J.; Mori M.A.; Saul V.V.; Bader M.; Calixto J.B.; De Giorgio R.; Corinaldesi R.; Geppetti P.; Trevisani M.
Expression and functional pharmacology of the bradykinin B1 receptor in the normal and inflamed human gallbladder
Gut 57 (5): 628-633 (2008-05)

Murtaza I.; Wang H.X.; Feng X.; Alenina N.; Bader M.; Prabhakar B.S.; Li P.F.
Down-regulation of catalase and oxidative modification of protein kinase CK2 lead to the failure of apoptosis repressor with caspase recruitment domain to inhibit cardiomyocyte hypertrophy
Journal of Biological Chemistry 283 (10): 5996-6004 (2008-03-07)

Sabatini R.A.; Guimaraes P.B.; Fernandes L.; Reis F.C.; Bersanetti P.A.; Mori M.A.; Navarro A.; Hilzendeger A.M.; Santos E.L.; Andrade M.C.; Chagas J.R.; Pesquero J.L.; Casarini D.E.; Bader M.; Carmona A.K.; Pesquero J.B.
ACE activity is modulated by kinin B2 receptor
Hypertension 51 (3): 689-695 (2008-03)

Feldt S.; Batenburg W.W.; Mazak I.; Maschke U.; Wellner M.; Kvakan H.; Dechend R.; Fiebeler A.; Burckle C.; Contrepas A.; Danser A.H.; Bader M.; Nguyen G.; Luft F.C.; Mueller D.N.
Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide
Hypertension 51 (3): 682-688 (2008-03)

Santos S.H.S.; Fernandes L.R.; Mario E.G.; Ferreira A.V.; Porto L.C.; Alvarez-Leite J.I.; Botion L.M.; Bader M.; Alenina N.; Santos R.A.
Mas deficiency in FVB/N mice produces marked changes in lipid and glycemic metabolism
Diabetes 57 (2): 340-347 (2008-02-01)

Fischer R.; Dechend R.; Qadri F.; Markovic M.; Feldt S.; Herse F.; Park J.K.; Gapelyuk A.; Schwarz I.; Zacharzowsky U.B.; Plehm R.; Safak E.; Heuser A.; Schirdewan A.; Luft F.C.; Schunck W.H.; Mueller D.N.
Dietary n-3 polyunsaturated fatty acids and direct renin inhibition improve electrical remodeling in a model of high human renin hypertension
Hypertension 51 (2): 540-546 (2008-02)

Xu P.; Costa-Goncalves A.C.; Todiras M.; Rabelo L.A.; Sampaio W.O.; Moura M.M.; Santos S.S.; Luft F.C.; Bader M.; Gross V.; Alenina N.; Santos R.A.S.
Endothelial dysfunction and elevated blood pressure in MAS gene-deleted mice
Hypertension 51 (2): 574-580 (2008-02)


Shmidt T.; Hampich F.; Ridders M.; Schultrich S.; Hans V.H.; Tenner K.; Vilianovich L.; Qadri F.; Alenina N.; Hartmann E.; Koehler M.; Bader M.
Normal brain development in importin-alpha5 deficient-mice
Nature Cell Biology 9 (12): 1337-1338 (2007-12)

Ifuku M.; Faerber K.; Okuno Y.; Yamakawa Y.; Miyamoto T.; Nolte C.; Merrino V.F.; Kitada S.; Iwamoto T.; Komuro I.; Wang B.; Cheung G.; Ishikawa E.; Ooboshi H.; Bader M.; Wada K.; Kettenmann H.; Noda M.
Bradykinin-induced microglial migration mediated by B1-bradykinin receptors depends on Ca2+ influx via reverse-mode activity of the Na+/Ca2+ exchanger
Journal of Neuroscience 27 (48): 13065-13073 (2007-11-28)

Duchene J.; Lecomte F.; Ahmed S.; Cayla C.; Pesquero J.; Bader M.; Perretti M.; Ahluwalia A.
A novel inflammatory pathway involved in leukocyte recruitment: role for the kinin B1 receptor and the chemokine CXCL5
Journal of Immunology 179 (7): 4849-4856 (2007-10-01)

Nocito A.; Dahm F.; Jochum W.; Jang J.H.; Georgiev P.; Bader M.; Renner E.L.; Clavien P.A.
Serotonin mediates oxidative stress and mitochondrial toxicity in a murine model of nonalcoholic steatohepatitis
Gastroenterology 133 (2): 608-618 (2007-08)

Bocciardi R.; Giorda R.; Buttgereit J.; Gimelli S.; Divizia M.T.; Beri S.; Garofalo S.; Tavella S.; Lerone M.; Zuffardi O.; Bader M.; Ravazzolo R.; Gimelli G.
Overexpression of the C-type natriuretic peptide (CNP) is associated with overgrowth and bone anomalies in an individual with balanced t(2;7) translocation
Human Mutation 28 (7): 724-731 (2007-07)

Cayla C.; Todiras M.; Iliescu R.; Saul V.V.; Gross V.; Pilz B.; Chai G.; Merino V.F.; Pesquero J.B.; Baltatu O.C.; Bader M.
Mice deficient for both kinin receptors are normotensive and protected from endotoxin- induced hypotension
FASEB Journal 21 (8): 1689-1698 (2007-06)

Nocito A.; Georgiev P.; Dahm F.; Jochum W.; Bader M.; Graf R.; Clavien P.A.
Platelets and platelet-derived serotonin promote tissue repair after normothermic hepatic ischemia in mice
Hepatology 45 (2): 369-376 (2007-02)

Jankowski V.; Vanholder R.; van der Giet M.; Toelle M.; Karadogan S.; Gobom J.; Furkert J.; Oksche A.; Krause E.; Tran T.N.; Tepel M.; Schuchardt M.; Schlueter H.; Wiedon A.; Beyermann M.; Bader M.; Todiras M.; Zidek W.; Jankowski J.
Mass-spectrometric identification of a novel angiotensin peptide in human plasma
Arteriosclerosis Thrombosis and Vascular Biology 27 (2): 297-302 (2007-02)

Walther T.; Tschoepe C.; Sterner-Kock A.; Westermann D.; Heringer-Walther S.; Riad A.; Nikolic A.; Wang Y.; Ebermann L.; Siems W.E.; Bader M.; Shakibaei M.; Schultheiss H.P.; Doerner A.
Accelerated mitochondrial adenosine diphosphate/adenosine triphosphate transport improves hypertension-induced heart disease
Circulation 115 (3): 333-344 (2007-01-23)

Morecroft I.; Dempsie Y.; Bader M.; Walther D.J.; Kotnik K.; Loughlin L.; Nilsen M.; Maclean M.R.
Effect of tryptophan hydroxylase 1 deficiency on the development of hypoxia-induced pulmonary hypertension
Hypertension 49 (1): 232-236 (2007-01)

Li H.J.; Yin H.; Yao Y.Y.; Shen B.; Bader M.; Chao L.; Chao J.
Tissue kallikrein protects against pressure overload-induced cardiac hypertrophy through kinin B2 receptor and glycogen synthase kinase-3{beta} activation
Cardiovascular Research 73 (1): 130-142 (2007-01-01)


Burckle C.; Bader M.
Prorenin and its ancient receptor
Hypertension 48 (4): 549-551 (2006-10)

Carkaci-Salli N.; Flanagan J.M.; Martz M.K.; Salli U.; Walther D.J.; Bader M.; Vrana K.E.
Functional domains of human tryptophan hydroxylase 2 (hTPH2)
Journal of Biological Chemistry 281 (38): 28105-28112 (2006-09-22)

Si H.; Heyken W.T.; Woelfle S.E.; Tysiac M.; Schubert R.; Grgic I.; Vilianovich L.; Giebing G.; Maier T.; Gross V.; Bader M.; de Wit C.; Hoyer J.; Koehler R.
Impaired endothelium-derived hyperpolarizing factor-mediated dilations and increased blood pressure in mice deficient of the intermediate-conductance Ca2+-activated K+ channel
Circulation Research 99 (5): 537-544 (2006-09-01)

Santos R.A.; Castro C.H.; Gava E.; Pinheiro S.V.; Almeida A.P.; de Paula R.D.; Cruz J.S.; Ramos A.S.; Rosa K.T.; Irigoyen M.C.; Bader M.; Alenina N.; Kitten G.T.; Ferreira A.J.
Impairment of in vitro and in vivo heart function in angiotensin-(1-7) receptor Mas knockout mice
Hypertension 547 (5): 996-1002 (2006-05)

Lesurtel M.; Graf R.; Aleil B.; Walther D.J.; Tian Y.; Jochum W.; Gachet C.; Bader M.; Clavien P.A.
Platelet-derived serotonin mediates liver regeneration
Science 312 (5770): 104-107 (2006-04-07)

Pfab T.; Thoene-Reineke C.; Theilig F.; Lange I.; Witt H.; Maser-Gluth C.; Bader M.; Stasch J.P.; Ruiz P.; Bachmann S.; Yanagisawa M.; Hocher B.
Diabetic endothelin B receptor-deficient rats develop severe hypertension and progressive renal failure
Journal of the American Society of Nephrology 17 (4): 1082-1089 (2006-04)

Panek A.N.; Bader M.
Matrix reloaded. The matrix metalloproteinase paradox
Hypertension 47 (4): 640-641 (2006-04)

Langenickel T.H.; Buttgereit J.; Pagel-Langenickel I.; Lindner M.; Monti J.; Beuerlein K.; Al-Saadi N.; Plehm R.; Popova E.; Tank J.; Dietz R.; Willenbrock R.; Bader M.
Cardiac hypertrophy in transgenic rats expressing a dominant-negative mutant of the natriuretic peptide receptor B
Proceedings of the National Academy of Sciences of the United States of America 103 (12): 4735-4740 (2006-03-21)

Donath S.; Li P.; Willenbockel C.; Al-Saadi N.; Gross V.; Willnow T.E.; Bader M.; Martin U.; Bauersachs J.; Wollert K.C.; Dietz R.; von Harsdorf R.
Apoptosis repressor with caspase recruitment domain is required for cardioprotection in response to biomechanical and ischemic stress
Circulation 113 (9): 1203-1212 (2006-03-07)

Burckle C.A.; Danser A.H.J.; Mueller D.N.; Garrelds I.M.; Gasc J.M.; Popova E.; Plehm R.; Peters J.; Bader M.; Nguyen G.
Elevated blood pressure and heart rate in human renin receptor transgenic rats
Hypertension 47 (3): 552-556 (2006-03)


de Castro C.H.; Souza dos Santos R.A.; Ferreira A.J.; Bader M.; Alenina N.; de Almeida A.P.
Evidence for a functional interaction of the angiotensin-(1-7) receptor Mas with AT1 and AT2 receptors in the mouse heart
Hypertension 46 (4): 937-942 (2005-09-12)

Maul B.; Krause W.; Pankow K.; Becker M.; Gembardt F.; Alenina N.; Walther T.; Bader M.; Siems W.E.
Central angiotensin II controls alcohol consumption via its AT1 receptor
FASEB Journal 19 (11): 1474-1481 (2005-09-01)

Tschoepe C.; Walther T.; Escher F.; Spillmann F.; Du J.; Altmann C.; Schimke I.; Bader M.; Sanchez-Ferrer C.F.; Schultheiss H.P.; Noutsias M.
Transgenic activation of the kallikrein-kinin system inhibits intramyocardial inflammation, endothelial dysfunction, and oxidative stress in experimental diabetic cardiomyopathy
FASEB Journal 19 (14): 2057-2059 (2005-08-29)

Grohmann M.; Spada F.; Schermelleh L.; Alenina N.; Bader M.; Cardoso M.C.; Leonhardt H.
Restricted mobility of Dnmt1 in preimplantation embryos: implications for epigenetic reprogramming
BMC Developmental Biology 5: 18 (2005-08-24)

Ferreira J.; Beirith A.; Mori M.A.; Araujo R.C.; Bader M.; Pesquero J.B.; Calixto J.B.
Reduced nerve injury-induced neuropathic pain in kinin B1 receptor knock-out mice
Journal of Neuroscience 25 (9): 2405-2412 (2005-03-02)

Engeli S.; Boehnke J.; Gorzelniak K.; Janke J.; Schling P.; Bader M.; Luft F.C.; Sharma A.M.
Weight loss and the renin-angiotensin-aldosterone system
Hypertension 45: 356-362 (2005-01-01)

Pompe S.; Bader M.; Tannert C.
Stem-cell research: the state of the art. Future regulations of embryonic-stem-cell research will be influenced more by economic interests and cultural history than by ethical concerns
EMBO Reports 6 (4): 297-300 (2005-01-01)

Crowley S.; Gurley S.; Oliverio M.; Pazmino A.; Griffiths R.; Flannery P.; Spurney R.; Kim H.S.; Smithies O.; Le T.; Coffman T.; Boucher J.; Masri B.; Daviaud D.; Gesta S.; Guigne C.; Mazzucotelli A.; Castan-Laurell I.; Tack I.; Knibiehler B.; Carpene C.; Audigier Y.; Saulnier-Blache J.; Valet P.; Engeli S.; Boehnke J.; Gorzelniak K.; Janke J.; Schling P.; Bader M.; Luft F.C.; Sharma A.
Is the kidney always the cause of hypertension? Distinct roles for the kidney and systemic tissues in blood pressure regulation by the Renin-Angiotensin system. J Clin Invest 115: 1092-1099, 2005
Journal of the American Society of Nephrology 16: 1525-1532 (2005-01-01)

Xu J.; Carretero O.A.; Sun Y.; Shesely E.G.; Rhaleb N.E.; Liu Y.H.; Liao T.D.; Yang J.J.; Bader M.; Yang X.P.
Role of the B1 kinin receptor in the regulation of cardiac function and remodeling after myocardial infarction
Hypertension 45 (4): 747-753 (2005-01-01)


Pinheiro S.V.B.; Simoes e Silva A.C.; Sampaio W.O.; de Paula R.D.; Mendes E.P.; Bontempo E.D.; Pesquero J.B.; Walther T.; Alenina N.; Bader M.; Bleich M.; Santos R.A.S.
Nonpeptide AVE 0991 is an angiotensin-(1-7) receptor Mas agonist in the mouse kidney
Hypertension 44 (4): 490-496 (2004-10-01)

Tschoepe C.; Spillmann F.; Rehfeld U.; Koch M.; Westermann D.; Altmann C.; Dendorfer A.; Walther T.; Bader M.; Paul M.; Schultheiss H.P.; Vetter R.
Improvement of defective sarcoplasmic reticulum Ca2+ transport in diabetic heart of transgenic rats expressing the human kallikrein-1 gene
FASEB Journal 18 (15): 1967-1969 (2004-09-24)

Harvey M.; Shink E.; Tremblay M.; Gagne B.; Raymond C.; Labbe M.; Walther D.J.; Bader M.; Barden N.
Support for the involvement of TPH2 gene in affective disorders
Molecular Psychiatry 9 (11): 980-981 (2004-07-20)

Tschoepe C.; Walther T.; Koeniger J.; Spillmann F.; Westermann D.; Escher F.; Pauschinger M.; Pesquero J.B.; Bader M.; Schultheiss H.P.; Noutsias M.
Prevention of cardiac fibrosis and left ventricular dysfunction in diabetic cardiomyopathy in rats by transgenic expression of the human tissue kallikrein gene
FASEB Journal 18 (7): 828-835 (2004-05)

Langenickel T.; Buttgereit J.; Pagel I.; Dietz R.; Willenbrock R.; Bader M.
Forced homodimerization by site-directed mutagenesis alters guanylyl cyclase activity of natriuretic peptide receptor B
Hypertension 43 (2): 460-465 (2004-02)

Ciruela F.; Burgueno J.; Casado V.V.; Canals M.; Marcellino D.; Goldberg S.R.; Bader M.; Fuxe K.; Agnati L.F.; Lluis C.; Franco R.; Ferre S.; Woods A.S.
Combining mass spectrometry and pull-down techniques for the study of receptor heteromerization. Direct epitope-epitope electrostatic interactions between adenosine A2A and dopamine D2 receptors
Analytical Chemistry 76 (18): 5354-5363 (2004-01-01)

Medeiros R.; Cabrini D.A.; Ferreira J.; Fernandes E.S.; Mori M.A.S.; Pesquero J.B.; Bader M.; Avellar M.C.W.; Campos M.M.; Calixto J.B.
Bradykinin B1 receptor expression induced by tissue damage in the rat portal vein - A critical role for mitogen-activated protein kinase and nuclear factor-kappaB signaling pathways
Circulation Research 94 (10): 1375-1382 (2004-01-01)

Matsuda M.; Imaoka T.; Vomachka A.J.; Gudelsky G.A.; Hou Z.Y.; Mistry M.; Bailey J.P.; Nieport K.M.; Walther D.J.; Bader M.; Horseman N.D.
Serotonin regulates mammary gland development via an autocrine-paracrine loop
Developmental Cell 6 (2): 193-203 (2004-01-01)

Souza D.G.; Lomez E.S.L.; Pinho V.; Pesquero J.B.; Bader M.; Pesquero J.L.; Teixeira M.M.
Role of bradykinin B2 and B1 receptors in the local, remote, and systemic inflammatory responses that follow intestinal ischemia and reperfusion injury
Journal of Immunology 172 (4): 2542-2548 (2004-01-01)


Schrauwen P.; Hoeks J.; Schaart G.; Kornips E.; Binas B.; van de Vusse G.J.; van Bilsen M.; Luiken J.J.F.P.; Coort S.L.M.; Glatz J.F.C.; Saris W.H.M.; Hesselinkt M.K.C.
Uncoupling protein 3 as a mitochondrial fatty acid anion exporter
FASEB Journal 17 (15): 2272-2274 (2003-12)

Santos R.A.S.; e Silva A.C.S.; Maric C.; Silva D.M.R.; Machado R.P.; de Buhr I.; Heringer-Walther S.; Pinheiro S.V.B.; Lopes M.T.; Bader M.; Mendes E.P.; Lemos V.S.; Campagnole-Santos M.J.; Schultheiss H.P.; Speth R.; Walther T.
Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas
Proceedings of the National Academy of Sciences of the United States of America 100 (14): 8258-8263 (2003-07-08)

Ruhnke M.; Ungefroren H.; Zehle G.; Bader M.; Kremer B.; Fandrich F.
Long-term culture and differentiation of rat embryonic stem cell-like cells into neuronal, glial, endothelial, and hepatic lineages
Stem Cells 21 (4): 428-436 (2003-07)

Holtje M.; Winter S.; Walther D.; Pahner I.; Hortnagl H.; Ottersen O.P.; Bader M.; Ahnert-Hilger G.
The vesicular monoamine content regulates VMAT2 activity through G {alpha}(q) mouse platelets - evidence for autoregulation of vesicular transmitter update
Journal of Biological Chemistry 278 (18): 15850-15858 (2003-05-02)

von Hoersten S.; Schmitt I.; Nguyen H.P.; Holzmann C.; Schmidt T.; Walther T.; Bader M.; Pabst R.; Kobbe P.; Krotova J.; Stiller D.; Kask A.; Vaarmann A.; Rathke-Hartlieb S.; Schulz J.B.; Grasshoff U.; Bauer I.; Vieira-Saecker A.M.M.; Paul M.; Jones L.; Lindenberg K.S.; Landwehrmeyer B.; Bauer A.; Li X.J.; Riess O.
Transgenic rat model of Huntington's disease
Human Molecular Genetics 12 (6): 617-624 (2003-03-15)

Baltatu O.; Cayla C.; Iliescu R.; Andreev D.; Bader M.
Abolition of end-organ damage by antiandrogen treatment in female hypertensive transgenic rats
Hypertension 41 (3): 830-833 (2003-03)

Walther D.J.; Peter J.U.; Bashammakh S.; Hoertnagl H.; Voits M.; Fink H.; Bader M.
Synthesis of serotonin by a second tryptophan hydroxylase isoform
Science 299 (5603): 76-76 (2003-01-03)

Walther D.J.; Peter J.U.; Winter S.; Hoeltje M.; Paulmann N.; Grohmann M.; Vowinckel J.; Alamo-Bethencourt V.; Wilhelm C.S.; Ahnert-Hilger G.; Bader M.
Serotonylation of small GTPases is a signal transduction pathway that triggers platelet {alpha}-granule release
Cell 115 (7): 851-862 (2003-01-01)

Todorov A.G.; Andrade D.; Pesquero J.B.; Araujo R.D.; Bader M.; Stewart J.; Gera L.; Mueller-Esterl W.; Morandi V.; Goldenberg R.C.S.; Neto H.C.F.; Scharfstein J.
Trypanosoma cruzi induces edematogenic responses in mice and invades cardiomyocytes and endothelial cells in vitro by activating distinct kinin receptor subtypes (B-1/B-2)
FASEB Journal 17 (1): U371-U392 (2003-01)

Ogier M.; Bezin L.; Cottet-Emard J.M.; Bader M.; Vincent M.; Pequignot J.M.; McGregor J.; Bricca G.
Delayed maturation of catecholamine phenotype in nucleus tractus solitarius of rats with glial angiotensinogen depletion
Hypertension 42 (5): 978-984 (2003-01-01)

Martin G.G.; Danneberg H.; Kumar L.S.; Atshaves B.P.; Erol E.; Bader M.; Schroeder F.; Binas B.
Decreased liver fatty acid binding capacity and altered liver lipid distribution in mice lacking the liver fatty acid-binding protein gene
Journal of Biological Chemistry 278 (24): 21429-21438 (2003-01-01)


Baptista H.A.; Avellar M.C.W.; Araujo R.C.; Pesquero J.L.; Schanstra J.P.; Bascands J.L.; Esteve J.P.; Paiva A.C.M.; Bader M.; Pesquero J.B.
Transcriptional regulation of the rat bradykinin B2 receptor gene: Identification of a silencer element
Molecular Pharmacology 62 (6): 1344-1355 (2002-12-01)

Baltatu O.; Cayla C.; Iliescu R.; Andreev D.; Jordan C.; Bader M.
Abolition of hypertension-induced end-organ damage by androgen receptor blockade in transgenic rats harboring the mouse Ren-2 gene
Journal of the American Society of Nephrology 13 (11): 2681-2687 (2002-11-01)

Thongboonkerd V.; Gozal E.; Sachleben L.R.; Arthur J.M.; Pierce W.M.; Cai J.; Chao J.; Bader M.; Pesquero J.B.; Gozal D.; Klein J.B.
Proteomic analysis reveals alterations in the renal kallikrein pathway during hypoxia-induced hypertension
Journal of Biological Chemistry 277 (38): 34708-34716 (2002-09-20)

Schanstra J.P.; Neau E.; Drogoz P.; Gomez M.A.A.; Novoa J.M.L.; Calise D.; Pecher C.; Bader M.; Girolami J.P.; Bascands J.L.
In vivo bradykinin B2 receptor activation reduces renal fibrosis
Journal of Clinical Investigation 110 (3): 371-379 (2002-08-01)

Walther T.; Olah L.; Harms C.; Maul B.; Bader M.; Hoertnagl H.; Schultheiss H.P.; Mies G.
Ischemic injury in experimental stroke depends on angiotensin II
FASEB Journal 16 (2): 169-176 (2002-02)

Faendrich F.; Lin X.; Chai G.X.; Schulze M.; Ganten D.; Bader M.; Holle J.; Huang D.S.; Parwaresch R.; Zavazava N.; Binas B.
Preimplantation-stage stem cells induce long-term allogeneic graft acceptance without supplementary host conditioning
Nature Medicine 8: 171-178 (2002-02-01)

Emanueli C.; Salis M.B.; Stacca T.; Pintus G.; Kirchmair R.; Isner J.M.; Pinna A.; Gaspa L.; Regoli D.; Cayla C.; Pesquero J.B.; Bader M.; Madeddu P.
Targeting kinin B1 receptor for therapeutic neovascularization
Circulation 105: 360-366 (2002-01-22)

Lomez E.S.L.; Araujo R.C.; Bader M.; Pesquero J.B.; Pesquero J.L.
Tonin and kallikrein in the brain of transgenic rat line expressing human tissue kallikrein
Hypertension 39: 229-232 (2002-01-01)

Bader M.; Ganten D.
It's renin in the brain - Transgenic animals elucidate the brain renin-angiotensin system
Circulation Research 90 (1): 8-10 (2002-01-01)


Maul B.; Siems W.E.; Hoehe M.R.; Grecksch G.; Bader M.; Walther T.
Alcohol consumption is controlled by angiotensin II
FASEB Journal 15: 1640-1642 (2001-07-01)

dos Santos R.A.S.; Passaglio K.T.; Pesquero J.B.; Bader M.; Silva A.C.S.E.
Interactions between angiotensin-(1-7), kinins, and angiotensin II in kidney and blood vessels
Hypertension 38: 660-664 (2001-01-01)

Baltatu O.; Janssen B.J.; Bricca G.; Plehm R.; Monti J.; Ganten D.; Bader M.
Alterations in blood pressure and heart rate variability in transgenic rats with low brain angiotensinogen
Hypertension 37 (2): 408-413 (2001-01-01)

Milia A.F.; Gross V.; Plehm R.; De Silva J.A.; Bader M.; Luft F.C.
Normal blood pressure and renal function in mice lacking the bradykinin B2 receptor
Hypertension 37: 1473-1479 (2001-01-01)


Pinto Y.M.; Bader M.; Pesquero J.B.; Tschoepe C.; Scholtens E.; van Gilst W.H.; Buikema H.
Increased kallikrein expression protects against cardiac ischemia
FASEB Journal 14 (13): 1861-1863 (2000-10-01)

Silva J.A.; Araujo R.C.; Baltatu O.; Oliveira S.M.; Tschoepe C.; Fink E.; Hoffmann S.; Plehm R.; Chai K.X.; Chao L.; Chao J.; Ganten D.; Pesquero J.B.; Bader M.
Reduced cardiac hypertrophy and altered blood pressure control in transgenic rats with the human tissue kallikrein gene
FASEB Journal 14 (13): 1858-1860 (2000-10-01)

Pesquero J.B.; Araujo R.C.; Heppenstall P.A.; Stucky C.L.; Silva J.A.; Walther T.; Oliveira S.M.; Pesquero J.L.; Paiva A.C.M.; Calixto J.B.; Lewin G.R.; Bader M.
Hypoalgesia and altered inflammatory responses in mice lacking kinin B1 receptors
Proceedings of the National Academy of Sciences of the United States of America 97 (14): 8140-8145 (2000-07-05)

Morano I.; Chai G.X.; Baltas L.G.; Lamounier-Zepter V.; Lutsch G.; Kott M.; Haase H.; Bader M.
Smooth-muscle contraction without smooth-muscle myosin
Nature Cell Biology 2 (6): 371-375 (2000-06-01)

Brandt R.; Eisenbrandt R.; Leenders F.; Zschiesche W.; Binas B.; Juergensen C.; Theuring F.
Mammary gland specific hEGF receptor transgene expression induces neoplasia and inhibits differentiation
Oncogene 19: 2129-2137 (2000-04-20)

Mervaala E.; Mueller D.N.; Schmidt F.; Park J.K.; Gross V.; Bader M.; Breu V.; Ganten D.; Haller H.; Luft F.C.
Blood pressure-independent effects in rats with human renin and angiotensinogen genes
Hypertension 35 (2): 587-594 (2000-02-01)

Baltatu O.; Silva J.A.; Ganten D.; Bader M.
The brain renin-angiotensin system modulates angiotensin II-induced hypertension and cardiac hypertrophy
Hypertension 35 (1): 409-412 (2000-01-01)


Maeda K.; Hata R.; Bader M.; Walther T.; Hossmann K.A.
Larger anastomoses in angiotensinogen-knockout mice attenuate early metabolic disturbances after middle cerebral artery occlusion
Journal of Cerebral Blood Flow and Metabolism 19 (10): 1092-1098 (1999-10)

Schaap F.G.; Binas B.; Danneberg H.; van der Vusse G.J.; Glatz J.F.C.
Impaired long-chain fatty acid utilization by cardiac myocytes isolated from mice lacking the heart-type fatty acid binding protein gene
Circulation Research 85: 329-337 (1999-08-20)

Binas B.; Danneberg H.; McWhir J.; Mullins L.; Clark A.J.
Requirement for the heart-type fatty acid binding protein in cardiac fatty acid utilization
FASEB Journal 13 (8): 805-812 (1999-05)

Schinke M.; Baltatu O.; Boehm M.; Peters J.; Rascher W.; Bricca G.; Lippoldt A.; Ganten D.; Bader M.
Blood pressure reduction and diabetes insipidus in transgenic rats deficient in brain angiotensinogen
Proceedings of the National Academy of Sciences of the United States of America 96: 3975-3980 (1999-03-30)

Nykjaer A.; Dragun D.; Walther D.; Vorum H.; Jacobsen C.; Herz J.; Melsen F.; Christensen E.I.; Willnow T.E.
An endocytic pathway essential for renal uptake and activation of the steroid 25-(OH) vitamin D-3
Cell 96 (4): 507-515 (1999-02-19)


Walther T.; Balschun D.; Voigt J.P.; Fink H.; Zuschratter W.; Birchmeier C.; Ganten D.; Bader M.
Sustained long-term potentiation and anxiety in mice lacking the Mas protooncogene
Journal of Biological Chemistry 273: 11867-11873 (1998-01-01)

Gross V.; Lippoldt A.; Bohlender J.; Bader M.; Hansson A.; Luft F.C.
Cortical and medullary hemodynamics in deoxycorticosterone acetate-salt hypertensive mice
Journal of the American Society of Nephrology 9: 346-354 (1998-01-01)


Rossi G.P.; Albertin G.; Belloni A.; Zanin L.; Biasolo M.A.; Prayer-Galetti T.; Bader M.; Nussdorfer G.G.; Palu G.; Pessina A.C.
Gene expression, localization, and characterization of endothelin A and B receptors in the human adrenal cortex
Journal of Clinical Investigation 94 (3): 1226-1234 (1994-09)

Maltsev V.A.; Wobus A.M.; Rohwedel J.; Bader M.; Hescheler J.
Cardiomyocytes differentiated in vitro from embryonic stem cells developmentally express cardiac-specific genes and ionic currents
Circulation Research 75 (2): 233-244 (1994-08-01)

Pesquero J.B.; Lindsey C.J.; Zeh K.; Paiva A.C.M.; Ganten D.; Bader M.
Molecular structure and expression of rat bradykinin B2 receptor gene. Evidence for alterative splicing
Journal of Biological Chemistry 43: 26920-26925 (1994-01-01)


Peters J.; Muenter K.; Bader M.; Hackenthal E.; Mullins J.J.; Ganten D.
Increased adrenal renin in transgenic hypertensive rats, TGR(mREN2)27, and its regulation by cAMP, angiotensin II and calcium
Journal of Clinical Investigation 91 (3): 742-747 (1993-03)


Ganten D.; Wagner J.; Zeh K.; Bader M.; Michel J.B.; Paul M.; Zimmermann F.; Ruf P.; Hilgenfeldt U.; Ganten U.; Kaling M.; Bachmann S.; Fukamizu A.; Mullins J.J.; Murakami K.
Species specificity of renin kinetics in transgenic rats harboring the human renin and angiotensinogen genes
Proceedings of the National Academy of Sciences of the United States of America 89: 7806-7810 (1992-08)


Ganten D.; Lindpaintner K.; Ganten U.; Peters J.; Zimmermann F.; Bader M.; Mullins J.J.
Transgenic rats: new animal models in hypertension research. Invited lecture
Hypertension 17: 843-855 (1991-01-01)