Publications



2017

Wetzel C.; Pifferi S.; Picci C.; Goek C.; Hoffmann D.; Bali K.K.; Lampe A.; Lapatsina L.; Fleischer R.; Smith E.S.J.; Begay V.; Moroni M.; Estebanez L.; Kuehnemund J.; Walcher J.; Specker E.; Neuenschwander M.; von Kries J.P.; Haucke V.; Kuner R.; Poulet J.F.A.; Schmoranzer J.; Poole K.; Lewin G.R.
Small-molecule inhibition of STOML3 oligomerization reverses pathological mechanical hypersensitivity
Nature Neuroscience 20 (2): 209-218 (2017-02)



2016

Weber A.; Cohen I.; Popp O.; Dittmar G.; Reiss Y.; Sommer T.; Ravid T.; Jarosch E.
Sequential poly-ubiquitylation by specialized conjugating enzymes expands the versatility of a quality control ubiquitin ligase
Molecular Cell 63 (5): 827-839 (2016-09-01)



Braten O.; Livneh I.; Ziv T.; Admon A.; Kehat I.; Caspi L.H.; Gonen H.; Bercovich B.; Godzik A.; Jahandideh S.; Jaroszewski L.; Sommer T.; Kwon Y.T.; Guharoy M.; Tompa P.; Ciechanover A.
Numerous proteins with unique characteristics are degraded by the 26S proteasome following monoubiquitination
Proceedings of the National Academy of Sciences of the United States of America 113 (32): E4639-E4647 (2016-08-09)



von Delbrueck M.; Kniss A.; Rogov V.V.; Pluska L.; Bagola K.; Loehr F.; Guentert P.; Sommer T.; Doetsch V.
The CUE domain of Cue1 aligns growing ubiquitin chains with Ubc7 for rapid elongation
Molecular Cell 62 (6): 918-928 (2016-06-16)



Pfeiffer A.; Stephanowitz H.; Krause E.; Volkwein C.; Hirsch C.; Jarosch E.; Sommer T.
A complex of Htm1 and the oxidoreductase Pdi1 accelerates degradation of misfolded glycoproteins
Journal of Biological Chemistry 291 (23): 12195-12207 (2016-06-03)



Lodka D.; Pahuja A.; Geers-Knoerr C.; Scheibe R.; Nowak M.; Hamati J.; Koehncke C.; Purfuerst B.; Kanashova T.; Schmidt S.; Glass D.J.; Morano I.; Heuser A.; Kraft T.; Bassel-Duby R.; Olson E.N.; Dittmar G.; Sommer T.; Fielitz J.
Muscle RING-finger 2 and 3 maintain striated-muscle structure and function
Journal of Cachexia Sarcopenia and Muscle 7 (2): 165-180 (2016-05)



2015

Kravtsova-Ivantsiv Y.; Shomer I.; Cohen-Kaplan V.; Snijder B.; Superti-Furga G.; Gonen H.; Sommer T.; Ziv T.; Admon A.; Naroditsky I.; Jbara M.; Brik A.; Pikarsky E.; Kwon Y.T.; Doweck I.; Ciechanover A.
KPC1-mediated ubiquitination and proteasomal processing of NF-{kappa}B1 p105 to p50 restricts tumor growth
Cell 161 (2): 333-347 (2015-04-09)



Mansour W.; Nakasone M.A.; von Delbrueck M.; Yu Z.; Krutauz D.; Reis N.; Kleifeld O.; Sommer T.; Fushman D.; Glickman M.H.
Disassembly of Lys11- and mixed-linkage polyubiquitin conjugates provide insights into function of proteasomal deubiquitinases Rpn11 and Ubp6
Journal of Biological Chemistry 290 (8): 4688-4704 (2015-02-20)



Mehnert M.; Sommermeyer F.; Berger M.; Lakshmipathy S.K.; Gauss R.; Aebi M.; Jarosch E.; Sommer T.
The interplay of Hrd3 and the molecular chaperone system ensures efficient degradation of malfolded secretory proteins
Molecular Biology of the Cell 26 (2): 185-194 (2015-01-15)



2014

Sommer T.; Weber A.; Jarosch E.
Rsp5/Nedd4 clears cells of heat-damaged proteins
Nature Cell Biology 16 (12): 1130-1132 (2014-12-01)



Denzel M.S.; Storm N.J.; Gutschmidt A.; Baddi R.; Hinze Y.; Jarosch E.; Sommer T.; Hoppe T.; Antebi A.
Hexosamine pathway metabolites enhance protein quality control and prolong life
Cell 156 (6): 1167-1178 (2014-03-13)



Mehnert M.; Sommer T.; Jarosch E.
Der1 promotes movement of misfolded proteins through the endoplasmic reticulum membrane
Nature Cell Biology 16 (1): 77-86 (2014-01)



Sommer T.; Wolf D.H.
The ubiquitin-proteasome-system
Biochimica et Biophysica Acta - Molecular Cell Research 1843 (1): 1 (2014-01)



Amm I.; Sommer T.; Wolf D.H.
Protein quality control and elimination of protein waste: the role of the ubiquitin-proteasome system
Biochimica et Biophysica Acta - Molecular Cell Research 1843 (1): 182-196 (2014-01)



2013

Bagola K.; von Delbrueck M.; Dittmar G.; Scheffner M.; Ziv I.; Glickman M.H.; Ciechanover A.; Sommer T.
Ubiquitin binding by a CUE domain regulates ubiquitin chain formation by ERAD E3 ligases
Molecular Cell 50 (4): 528-539 (2013-05-23)



Kravtsova-Ivantsiv Y.; Sommer T.; Ciechanover A.
The lysine48-based polyubiquitin chain proteasomal signal: not a single child anymore
Angewandte Chemie International Edition 52 (1): 192-198 (2013-01-02)



2012

Shabek N.; Herman-Bachinsky Y.; Buchsbaum S.; Lewinson O.; Haj-Yahya M.; Hejjaoui M.; Lashuel H.A.; Sommer T.; Brik A.; Ciechanover A.
The size of the proteasomal substrate determines whether its degradation will be mediated by mono- or polyubiquitylation
Molecular Cell 48 (1): 87-97 (2012-10-12)



Finley D.; Ulrich H.D.; Sommer T.; Kaiser P.
The ubiquitin-proteasome system of Saccharomyces cerevisiae
Genetics 192 (2): 319-360 (2012-10-01)



Hampton R.Y.; Sommer T.
Finding the will and the way of ERAD substrate retrotranslocation
Current Opinion in Cell Biology 24 (4): 460-466 (2012-08)



Hanna J.; Schuetz A.; Zimmermann F.; Behlke J.; Sommer T.; Heinemann U.
Structural and biochemical basis of Yos9 protein dimerization and possible contribution to self-association of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation ubiquitin-ligase complex
Journal of Biological Chemistry 287 (11): 8633-8640 (2012-03-09)



2011

Jaenicke L.A.; Brendebach H.; Selbach M.; Hirsch C.
Yos9p assists in the degradation of certain non-glycosylated proteins from the endoplasmic reticulum
Molecular Biology of the Cell 22 (16): 2937-2945 (2011-08)



Bagola K.; Mehnert M.; Jarosch E.; Sommer T.
Protein dislocation from the ER
Biochimica et Biophysica Acta - Biomembranes 1808 (3): 925-936 (2011-03)



2010

Buchberger A.; Bukau B.; Sommer T.
Protein quality control in the cytosol and the endoplasmic reticulum: brothers in arms
Molecular Cell 40 (2): 238-252 (2010-10-22)



Mehnert M.; Sommer T.; Jarosch E.
ERAD ubiquitin ligases: multifunctional tools for protein quality control and waste disposal in the endoplasmic reticulum
BioEssays 32 (10): 905-913 (2010-10)



2009

Horn S.C.; Hanna J.; Hirsch C.; Volkwein C.; Schuetz A.; Heinemann U.; Sommer T.; Jarosch E.
Usa1 functions as a scaffold of the HRD-ubiquitin ligase
Molecular Cell 36 (5): 782-793 (2009-12-11)



Lutz A.K.; Exner N.; Fett M.E.; Schlehe J.S.; Kloos K.; Laemmermann K.; Brunner B.; Kurz-Drexler A.; Vogel F.; Reichert A.S.; Bouman L.; Vogt-Weisenhorn D.; Wurst W.; Tatzelt J.; Haass C.; Winklhofer K.F.
Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation
Journal of Biological Chemistry 284 (34): 22938-22951 (2009-08-21)



Zick M.; Duvezin-Caubet S.; Schaefer A.; Vogel F.; Neupert W.; Reichert A.S.
Distinct roles of the two isoforms of the dynamin-like GTPase Mgm1 in mitochondrial fusion
FEBS Letters 583 (13): 2237-2243 (2009-07-07)



Rabl R.; Soubannier V.; Scholz R.; Vogel F.; Mendl N.; Vasiljev-Neumeyer A.; Koerner C.; Jagasia R.; Keil T.; Baumeister W.; Cyrklaff M.; Neupert W.; Reichert A.S.
Formation of cristae and crista junctions in mitochondria depends on antagonism between Fcj1 and Su e/g
Journal of Cell Biology 185 (6): 1047-1063 (2009-06-15)



Prestele M.; Vogel F.; Reichert A.S.; Herrmann J.M.; Ott M.
Mrpl36 is important for generation of assembly competent proteins during mitochondrial translation
Molecular Biology of the Cell 20 (10): 2615-2625 (2009-05)



Hirsch C.; Gauss R.; Horn S.C.; Neuber O.; Sommer T.
The ubiquitylation machinery of the endoplasmic reticulum
Nature 458 (7237): 453-460 (2009-03-26)



Clerc S.; Hirsch C.; Oggier D.M.; Deprez P.; Jakob C.; Sommer T.; Aebi M.
Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum
Journal of Cell Biology 184 (1): 159-172 (2009-01-12)



2008

Bagola K.; Sommer T.
Protein quality control: On IPODs and other JUNQ
Current Biology 18 (21): R1019-R1021 (2008-11-11)



Neuber A.; Franke J.; Wittstruck A.; Schlenstedt G.; Sommer T.; Stade K.
The nuclear export receptor Xpo1/Crm1 is physically and functionally linked to the spindle pole body in budding yeast
Molecular and Cellular Biology 28 (17): 5348-5358 (2008-09)



Sommer T.; Gauss R.
Lectins in the endoplasmic reticulum: the sweet side of protein quality control
Developmental Cell 14 (4): 463-464 (2008-04-15)



2007

Exner N.; Treske B.; Paquet D.; Holmstroem K.; Schiesling C.; Gispert S.; Carballo-Carbajal I.; Berg D.; Hoepken H.H.; Gasser T.; Krueger R.; Winklhofer K.F.; Vogel F.; Reichert A.S.; Auburger G.; Kahle P.J.; Schmid B.; Haass C.
Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin
Journal of Neuroscience 27 (45): 12413-12418 (2007-11-07)



Mirski S.E.L.; Sparks K.E.; Friedrich B.; Koehler M.; Mo Y.Y.; Beck W.T.; Cole S.P.C.
Topoisomerase II binds importin alpha isoforms and exportin/CRM1 but does not shuttle between the nucleus and cytoplasm in proliferating cells
Experimental Cell Research 313 (3): 627-637 (2007-02-01)



2006

Hirsch C.; Gauss R.; Sommer T.
Coping with stress: cellular relaxation techniques
Trends in Cell Biology 16 (12): 657-663 (2006-12)



Friedrich B.; Quensel C.; Sommer T.; Hartmann E.; Koehler M.
Nuclear localization signal and protein context both mediate importin {alpha} specificity of nuclear import substrates
Molecular and Cellular Biology 26 (23): 8697-8709 (2006-12)



Vogel F.; Bornhoevd C.; Neupert W.; Reichert A.S.
Dynamic subcompartmentalization of the mitochondrial inner membrane
Journal of Cell Biology 175 (2): 237-247 (2006-10-23)



Gauss R.; Jarosch E.; Sommer T.; Hirsch C.
A complex of Yos9p and the HRD ligase integrates endoplasmic reticulum quality control into the degradation machinery
Nature Cell Biology 8 (8): 849-854 (2006-08)



Bornhoevd C.; Vogel F.; Neupert W.; Reichert A.S.
Mitochondrial membrane potential is dependent on the oligomeric state of F1F0-ATP synthase supracomplexes
Journal of Biological Chemistry 281 (20): 13990-13998 (2006-05-19)



Gauss R.; Sommer T.; Jarosch E.
The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment
EMBO Journal 25 (9): 1827-1835 (2006-05-03)



Gauss R.; Neuber O.; Sommer T.
Proteasomal degradation of misfolded proteins
Chaperones : 185-220 (2006)



Sommer T.; Dittmar G.
Ubiquitination
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2 : 1964-1968 (2006)



Pannek A.; Stade K.
Nuclear import and export
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2 : 1320-1324 (2006)



2005

Neuber O.; Jarosch E.; Volkwein C.; Walter J.; Sommer T.
Ubx2 links the Cdc48 complex to ER-associated protein degradation
Nature Cell Biology 7 (10): 993-998 (2005-09-18)



Meusser B.; Hirsch C.; Jarosch E.; Sommer T.
ERAD: the long road to destruction
Nature Cell Biology 7 (8): 766-772 (2005-08)



Dimmer K.S.; Jakobs S.; Vogel F.; Altmann K.; Westermann B.
Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast
Journal of Cell Biology 168 (1): 103-115 (2005-01-03)



Turnbull A.P.; Kuemmel D.; Prinz B.; Holz C.; Schultchen J.; Lang C.; Niesen F.H.; Hofmann K.P.; Delbrueck H.; Behlke J.; Mueller E.C.; Jarosch E.; Sommer T.; Heinemann U.
Structure of palmitoylated BET3: insights into TRAPP complex assembly and membrane localization
EMBO Journal 24 (5): 875-884 (2005-01-01)



Sommer T.; Hirsch C.
San1p, checking up on nuclear proteins
Cell 120 (6): 734-736 (2005-01-01)



Fagerlund R.; Kinnunen L.; Koehler M.; Julkunen I.; Melen K.
NF-{kappa}B is transported into the nucleus by importin {alpha}3 and importin {alpha}4
Journal of Biological Chemistry 280 (16): 15942-15951 (2005-01-01)



Sommer T.; Jarosch E.
Pardon me - No access without ubiquitin
Developmental Cell 8 (1): 4-5 (2005-01-01)



Gauss R.; Trautwein M.; Sommer T.; Spang A.
New modules for the repeated internal and N-terminal epitope tagging of genes in Saccharomyces cerevisiae
Yeast 22 (1): 1-12 (2005-01-01)



2004

Meusser B.; Sommer T.
Vpu-mediated degradation of CD4 reconstituted in yeast reveals mechanistic differences to cellular ER-associated protein degradation
Molecular Cell 14 (2): 247-258 (2004-01-01)



Quensel C.; Friedrich B.; Sommer T.; Hartmann E.; Koehler M.
In vivo analysis of importin alpha proteins reveals cellular proliferation inhibition and substrate specificity
Molecular and Cellular Biology 24 (23): 10246-10255 (2004-01-01)



Baumeister W.; Bachmair A.; Chau V.; Cohen R.; Coffino P.; DeMartino G.; Deshaies R.; Dohmen J.; Emr S.; Finley D.; Hampton R.; Hill C.; Hochstrasser M.; Huber R.; Jackson P.; Jentsch S.; Johnson E.; Kwon Y.T.; Pagano M.; Pickart C.; Rechsteiner M.; Scheffner M.; Sommer T.; Tansey W.; Tyers M.; Vierstra R.; Weissman A.; Wilkinson K.D.; Wolf D.
Varshavsky's contributions
Science 306 (5700): 1290-1292 (2004-01-01)



Hirsch C.; Jarosch E.; Sommer T.; Wolf D.H.
Endoplasmic reticulum-associated protein degradation - one model fits all?
Biochimica et Biophysica Acta - Molecular Cell Research 1695 (1-3): 215-223 (2004-01-01)



Wolf D.H.; Sommer T.; Hilt W.
Death gives birth to life: the essential role of the ubiquitin-proteasome system in biology
Biochimica et Biophysica Acta - Molecular Cell Research 1695 (1-3): 1-2 (2004-01-01)



2003

Messerschmitt M.; Jakobs S.; Vogel F.; Fritz S.; Dimmer K.S.; Neupert W.; Westermann B.
The inner membrane protein Mdm33 controls mitochondrial morphology in yeast
Journal of Cell Biology 160 (4): 553-564 (2003-02-18)



Herlan M.; Vogel F.; Boernhovd C.; Neupert W.; Reichert A.S.
Processing of Mgm1 by the rhomboid-type protease Pcp1 is required for maintenance of mitochondrial morphology and of mitochondrial DNA
Journal of Biological Chemistry 278 (30): 27781-27788 (2003-01-01)



Jarosch E.; Lenk U.; Sommer T.
Endoplasmic reticulum-associated protein degradation
International Review of Cytology 223: 39-81 (2003)



2002

Sommer T.; Jarosch E.
BiP binding keeps ATF6 at bay
Developmental Cell 3 (1): 1-2 (2002-07-11)



Taxis C.; Vogel F.; Wolf D.H.
ER-Golgi traffic is a prerequisite for efficient ER degradation
Molecular Biology of the Cell 13 (6): 1806-1818 (2002-06-01)



Fujita Y.; Krause G.; Scheffner M.; Zechner D.; Leddy H.E.M.; Behrens J.; Sommer T.; Birchmeier W.
Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex
Nature Cell Biology 4 (3): 222-231 (2002-03-01)



Jarosch E.; Taxis C.; Volkwein C.; Bordallo J.; Finley D.; Wolf D.H.; Sommer T.
Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48
Nature Cell Biology 4 (2): 134-139 (2002-02-01)



Stade K.; Vogel F.; Schwienhorst I.; Meusser B.; Volkwein C.; Nentwig B.; Dohmen R.J.; Sommer T.
A lack of SUMO conjugation affects cNLS-dependent nuclear protein import in yeast
Journal of Biological Chemistry 277 (51): 49554-49561 (2002-01-01)



Bureik M.; Schiffler B.; Hiraoka Y.; Vogel F.; Bernhardt R.
Functional expression of human mitochondrial CYP11B2 in fission yeast and identification of a new internal electron transfer protein, etp1
Biochemistry 41 (7): 2311-2321 (2002-01-01)



Jarosch E.; Geiss-Friedlander R.; Meusser B.; Walter J.; Sommer T.
Protein dislocation from the endoplasmic reticulum - Pulling out the suspect
Traffic 3 (8): 530-536 (2002-01-01)



Lenk U.; Yu H.; Walter J.; Gelman M.S.; Hartmann E.; Kopito R.R.; Sommer T.
A role for mammalian Ubc6 homologues in ER-associated protein degradation
Journal of Cell Science 115 (14): 3007-3014 (2002-01-01)



Zimmer T.; Biskup C.; Dugarmaa S.; Vogel F.; Steinbis M.; Boehle T.; Wu Y.S.; Dumaine R.; Benndorf K.
Functional expression of GFP-linked human heart sodium channel (hH1) and subcellular localization of the alpha subunit in HEK293 cells and dog cardiac myocytes
Journal of Membrane Biology 186 (1): 1-12 (2002-01-01)



2001

Koehler M.; Schneider W.; Goebel U.; Kettritz R.
Renal anaemia of an unusual origin
Nephrology Dialysis Transplantation 16 (11): 2263-2264 (2001-11)



Maurer P.; Redd M.; Solsbacher J.; Bischoff F.R.; Greiner M.; Podtelejnikov A.V.; Mann M.; Stade K.; Weis K.; Schlenstedt G.
The nuclear export receptor Xpo1p forms distinct complexes with NES transport substrates and the yeast ran binding protein 1 (Yrb1p)
Molecular Biology of the Cell 12 (3): 539-549 (2001-03)



Koehler M.; Goerlich D.; Hartmann E.; Franke J.
Adenoviral E1A protein nuclear import is preferentially mediated by importin alpha3 in vitro
Virology 289: 186-191 (2001-01-01)



Sommer T.; Jarosch E.; Lenk U.
Compartment-specific functions of the ubiquitin-proteasome pathway
Reviews of Physiology Biochemistry and Pharmacology 142: 97-160 (2001)



Koehler M.; Buchwalow I.B.; Alexander G.; Christiansen M.; Shagdarsuren E.; Samoilova V.; Hartmann E.; Mervaala E.M.A.; Haller H.
Increased importin alpha protein expression in diabetic nephropathy
Kidney International 60: 2263-2273 (2001-01-01)



Franke J.; Reimann B.; Hartmann E.; Koehler M.; Wiedmann B.
Evidence for a nuclear passage of nascent polypeptide-associated complex subunits in yeast
Journal of Cell Science 114: 2641-2648 (2001-01-01)



Koritschoner N.P.; Alvarez-Dolado M.; Kurz S.M.; Heikenwaelder M.F.; Hacker C.; Vogel F.; Munoz A.; Zenke M.
Thyroid hormone regulates the obesity gene tub
EMBO Reports 2 (6): 499-504 (2001-01-01)



Walter J.; Urban J.; Volkwein C.; Sommer T.
Sec61p-independent degradation of the tail-anchored ER membrane protein Ubc6p
EMBO Journal 20 (12): 3124-3131 (2001-01-01)



2000

Madruga J.; Briegel K.; Diebold S.; Boehmelt G.; Vogel F.; Zenke M.
Dendritic cells conditionally transformed by v-relER oncogene express lymphoid marker genes
Immunobiology 202 (4): 394-407 (2000-11-01)



Solsbacher J.; Maurer P.; Vogel F.; Schlenstedt G.
Nup2p, a yeast nucleoporin, functions in bidirectional transport of importin alpha
Molecular and Cellular Biology 20 (22): 8468-8479 (2000-11-01)



Friedlander R.; Jarosch E.; Urban J.; Volkwein C.; Sommer T.
A regulatory link between ER-associated protein degradation and the unfolded-protein response
Nature Cell Biology 2 (7): 379-384 (2000-07-01)



Lenk U.; Sommer T.
Ubiquitin-mediated proteolysis of a short lived regulatory protein depends on its cellular localization
Journal of Biological Chemistry 275 (50): 39403-39410 (2000-01-01)



Sommer T.
The ubiquitin system in yeast
Proteasomes: the World of Regulatory Proteolysis : 204-215 (2000-01-01)



Meisinger C.; Sommer T.; Pfanner N.
Purification of Saccharomcyes cerevisiae mitochondria devoid of microsomal and cytosolic contaminations
Analytical Biochemistry 287 (2): 339-342 (2000-01-01)



1999

Welch K.; Franke J.; Koehler M.; Macara I.G.
RanBP3 contains an unusual nuclear localization signal that is imported preferentially by importin-alpha3
Molecular and Cellular Biology 19 (12): 8400-8411 (1999-12)



Sasnauskas K.; Buzaite O.; Vogel F.; Jandrig B.; Razanskas R.; Staniulis J.; Scherneck S.; Kruger D.H.; Ulrich R.
Yeast cells allow high-level expression and formation of polyomavirus-like particles
Biological Chemistry 380: 381-386 (1999-03-01)



Sandig G.; Kaergel E.; Menzel R.; Vogel F.; Zimmer T.; Schunck W.H.
Regulation of endoplasmic reticulum biogenesis in response to cytochrome P450 overproduction
Drug Metabolism Reviews 31: 393-410 (1999-01-01)



Dumler I.; Stepanova V.; Jerke U.; Mayboroda O.A.; Vogel F.; Bouvet P.; Tkachuk V.; Haller H.; Gulba D.C.
Urokinase-induced mitogenesis is mediated by casein kinase 2 and nucleolin
Current Biology 9: 1468-1476 (1999-01-01)



1998

Finley D.; Tanaka K.; Mann C.; Feldmann H.; Hochstrasser M.; Vierstra R.; Johnston S.; Hampton R.; Haber J.; Mccusker J.; Silver P.; Frontali L.; Thorsness P.; Varshavsky A.; Byers B.; Madura K.; Reed S.I.; Wolf D.; Jentsch S.; Sommer T.; Baumeister W.; Goldberg A.; Fried V.; Rubin D.M.; Toh-e A.
Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle
Trends in Biochemical Sciences 23 (7): 244-245 (1998-07-01)



1997

Biederer T.; Volkwein C.; Sommer T.
Role of Cue1p in ubiquitination and degradition at the ER surface
Science 278 (5344): 1806-1809 (1997-12-05)



Plemper R.K.; Bohmler S.; Bordallo J.; Sommer T.; Wolf D.H.
Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation
Nature 388: 891-895 (1997-01-01)



Ikonomova R.; Sommer T.; Kepes F.
The Srp40 protein plays a dose-sensitive role in preribosome assembly or transport and depends on its carboxy-terminal domain for proper localization to the yeast nucleoskeleton
DNA and Cell Biology 16: 1161-1173 (1997-01-01)



Sommer T.; Wolf D.H.
Endoplasmic reticulum degradation: reverse protein flow of no return
FASEB Journal 11: 1227-1233 (1997-01-01)



Collombet J.M.; Wheeler V.C.; Vogel F.; Coutelle C.
Introduction of plasmid DNA into isolated mitochondria by electroporation. A novel approach toward gene correction for mitochondrial disorders
Journal of Biological Chemistry 272: 5342-5347 (1997-01-01)



Menzel R.; Vogel F.; Kaergel E.; Schunck W.H.
Inducible membranes in yeast: relations to the unfolded-protein-response pathway
Yeast 13: 1211-1229 (1997-01-01)



Zimmer T.; Vogel F.; Ohta A.; Takagi M.; Schunck W.H.
Protein quality - a determinant of the intracellular fate of membrane-bound cytochromes P450 in yeast
DNA and Cell Biology 16: 501-514 (1997-01-01)



1996

Goerlich D.; Kraft R.; Kostka S.; Vogel F.; Hartmann E.; Laskey R.A.; Mattaj I.W.; Izaurralde E.
Importin provides a link between nuclear protein import and U snRNA export
Cell 87 (1): 21-32 (1996-10-04)



Ruiz P.; Brinkmann V.; Ledermann B.; Behrend M.; Grund C.; Thalhammer C.; Vogel F.; Birchmeier C.; Guenthert U.; Franke W.W.; Birchmeier W.
Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart
Journal of Cell Biology 135 (1): 215-225 (1996-10)



Menzel R.; Kaergel E.; Vogel F.; Boettcher C.; Schunck W.H.
Topogenesis of a microsomal cytochrome P450 and induction of endoplasmic reticulum membrane proliferation in Saccharomyces cerevisiae
Archives of Biochemistry and Biophysics 330: 97-109 (1996-01-01)



Kaergel E.; Menzel R.; Honeck H.; Vogel F.; Boehmer A.; Schunck W.H.
Candida maltosa NADPH-cytochrome P450 reductase: cloning of a full-length cDNA, heterologous expression in Saccharomyces cerevisiae and function of the N-terminal region for membrane anchoring and proliferation of the endoplasmic reticulum.
Yeast 12: 333-348 (1996-01-01)



Finke K.; Plath K.; Panzner S.; Prehn S.; Rapoport T.A.; Hartmann E.; Sommer T.
A second trimeric complex containing homologs of the Sec61p complex functions in protein transport across the ER membrane of S.cerevisiae
EMBO Journal 15 (7): 1482-1494 (1996-01-01)



Biederer T.; Volkwein C.; Sommer T.
Degradation of subunits of the Sec61p complex, an integral component of the ER membrane, by the ubiquitin-proteasome pathway
EMBO Journal 15: 2069-2076 (1996-01-01)



1995

Monier S.; Parton R.G.; Vogel F.; Behlke J.; Henske A.; Kurzchalia T.V.
VIP21-Caveolin, a membrane protein constituent of the caveolar coat, oligomerizes in vivo and in vitro
Molecular Biology of the Cell 6 (7): 911-927 (1995-07)



Ohkuma M.; Park S.M.; Zimmer T.; Menzel R.; Vogel F.; Schunck W.H.; Ohta A.; Takagi M.
Proliferation of intracellular membrane structures upon homologous overproduction of cytochrome P-450 in Candida maltosa
Biochimica et Biophysica Acta 1236 (1): 163-169 (1995-01-01)



Goerlich D.; Vogel F.; Mills A.D.; Hartmann E.; Laskey R.A.
Distinct functions for the two importin subunits in nuclear protein import
Nature 377: 246-248 (1995-01-01)



Zimmer T.; Kaminski K.; Scheller U.; Vogel F.; Schunck W.H.
In vivo reconstitution of highly active Candida maltosa cytochrome P450 monooxygenase systems in inducible membranes of Saccharomyces cerevisiae
DNA and Cell Biology 14: 619-628 (1995-01-01)



1994

Menzel R.; Kaergel E.; Wolff C.; Vogel F.; Schunck W.H.
High level expression of integral membrane proteins induces proliferation of the endoplasmic reticulum
Cytochrome P450 : 307-310 (1994-01-01)



Hartmann E.; Sommer T.; Prehn S.; Goerlich D.; Jentsch S.; Rapoport T.A.
Evolutionary conservation of components of the protein translocation complex
Nature 367: 654-657 (1994-01-01)



Micheel B.; Heymann S.; Scharte G.; Boettger V.; Vogel F.; Duebel S.; Breitling F.; Little M.; Behrsing O.
Production of monoclonal antibodies against epitopes of the main coat protein of filamentous fd phages
Journal of Immunological Methods 71: 103-109 (1994-01-01)



1993

Chen P.; Johnson P.; Sommer T.; Jentsch S.; Hochstrasser M.
Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MATalpha2 repressor
Cell 74 (2): 357-369 (1993-07-30)



Jentsch S.; Hauser H.P.; Heinlein R.; Jungmann J.; Schlenker S.; Seufert W.; Sommer T.; Springer S.
Ubiquitin-dependent protein degradation
Protein synthesis and targeting in yeast : (1993-01-01)



Sommer T.; Jentsch S.
A protein translocation defect linked to ubiquitin conjugation at the endoplasmic reticulum
Nature 365: 176-179 (1993-01-01)



Jentsch S.; Heinlein R.; Jungmann J.; Reins H.A.; Schlenker S.; Seufert W.; Sommer T.; Springer S.
Selective degradation by the ubiquitin system
Posttranscriptional control of gene expression : (1993-01-01)



1992

Sommer T.; Seufert W.
Genetic analysis of ubiquitin-dependent protein degradation
Experientia 48: 172-178 (1992-02-15)



Jentsch S.; Seufert W.; Sommer T.; Reins H.A.; Jungmann J.; Hauser H.P.
Ubiquitin-dependent protein degradation
DNA replication and the cell cycle : (1992-01-01)



Vogel F.; Gengnagel C.; Kaergel E.; Mueller H.G.; Schunck W.H.
Immunocytochemical localization of alkane-inducible cytochrome P-450 and its NADPH-dependet reductase in the yeast Candida maltosa
European Journal of Cell Biology 57: 285-291 (1992-01-01)



Vogel F.; Mueller T.; Grosse R.
Is the mammary-derived growth inhibitor (MDGI) related 70 kD antigen, identified in nuclei, a nuclear receptor for MDGI or its hydrophobic ligands?
Progress in Histochemistry and Cytochemistry : 159-163 (1992-01-01)



1991

Vogel F.; Kaergel E.; Schunck W.H.
In situ localization of cytochrome P-450, the first enzyme involved in aliphatic hydrocarbon degradation in the yeast Candida maltosa
Progress in Histochemistry and Cytochemistry 23: 383-389 (1991-01-01)



Schunck W.H.; Vogel F.; Gross B.; Kaergel E.; Mauersberger S.; Koepke K.; Gengnagel C.; Mueller H.G.
Comparison of two cytochromes P-450 from Candida maltosa: primary structures, substrate specificities, and effects of their expression in Saccharomyces cerevisoae on the proliferation of the endoplasmic reticulum
European Journal of Cell Biology 55: 336-345 (1991-01-01)