Publications



2017

Piwecka M.; Glazar P.; Hernandez-Miranda L.R.; Memczak S.; Wolf S.A.; Rybak-Wolf A.; Filipchyk A.; Klironomos F.; Cerda Jara C.A.; Fenske P.; Trimbuch T.; Zywitza V.; Plass M.; Schreyer L.; Ayoub S.; Kocks C.; Kuehn R.; Rosenmund C.; Birchmeier C.; Rajewsky N.
Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function
Science 357 (6357): eaam8526 (2017-09-22)



Zappulo A.; van den Bruck D.; Ciolli Mattioli C.; Franke V.; Imami K.; McShane E.; Moreno-Estelles M.; Calviello L.; Filipchyk A.; Peguero-Sanchez E.; Mueller T.; Woehler A.; Birchmeier C.; Merino E.; Rajewsky N.; Ohler U.; Mazzoni E.O.; Selbach M.; Akalin A.; Chekulaeva M.
RNA localization is a key determinant of neurite-enriched proteome
Nature Communications 8 (1): 583 (2017-09-19)



Spielmann M.; Hernandez-Miranda L.R.; Ceccherini I.; Weese-Mayer D.E.; Kragesteen B.K.; Harabula I.; Krawitz P.; Birchmeier C.; Leonard N.; Mundlos S.
Mutations in MYO1H cause a recessive form of central hypoventilation with autonomic dysfunction
Journal of Medical Genetics : (2017-08-04)



Stantzou A.; Schirwis E.; Swist S.; Alonso-Martin S.; Polydorou I.; Zarrouki F.; Mouisel E.; Beley C.; Julien A.; Le Grand F.; Garcia L.; Colnot C.; Birchmeier C.; Braun T.; Schuelke M.; Relaix F.; Amthor H.
BMP signaling regulates satellite cell dependent postnatal muscle growth
Development 144 (15): 2737-2747 (2017-08-01)



Hernandez-Miranda L.R.; Ruffault P.L.; Bouvier J.C.; Murray A.J.; Morin-Surun M.P.; Zampieri N.; Cholewa-Waclaw J.B.; Ey E.; Brunet J.F.; Champagnat J.; Fortin G.; Birchmeier C.
Genetic identification of a hindbrain nucleus essential for innate vocalization
Proceedings of the National Academy of Sciences of the United States of America 114 (30): 8095-8100 (2017-07-25)



Tsigkos S.; Hoffer M.; Sheean M.E.; Mariz S.; Larsson K.; Naumann-Winter F.; Fregonese L.; Sepodes B.
Establishing rarity in the context of orphan medicinal product designation in the European Union
Drug Discovery Today : (2017-06-21)



Alles J.; Karaiskos N.; Praktiknjo S.D.; Grosswendt S.; Wahle P.; Ruffault P.L.; Ayoub S.; Schreyer L.; Boltengagen A.; Birchmeier C.; Zinzen R.; Kocks C.; Rajewsky N.
Cell fixation and preservation for droplet-based single-cell transcriptomics
BMC Biology 15 (1): 44 (2017-05-19)



Griger J.; Schneider R.; Lahmann I.; Schoewel V.; Keller C.; Spuler S.; Nazare M.; Birchmeier C.
Loss of Ptpn11 (Shp2) drives satellite cells into quiescence
eLife 6: e21552 (2017-05-02)



Ravindran E.; Hu H.; Yuzwa S.A.; Hernandez-Miranda L.R.; Kraemer N.; Ninnemann O.; Musante L.; Boltshauser E.; Schindler D.; Huebner A.; Reinecker H.-C.; Ropers H.-H.; Birchmeier C.; Miller F.D.; Wienker T.F.; Huebner C.; Kaindl A.M.
Homozygous ARHGEF2 mutation causes intellectual disability and midbrain-hindbrain malformation
PLoS Genetics 13 (4): e1006746 (2017-04-28)



Schneider S.; Goetz K.; Birchmeier C.; Schwegler H.; Roskoden T.
Neuregulin-1 mutant mice indicate motor and sensory deficits, indeed few references for schizophrenia endophenotype model
Behavioural Brain Research 322 (Pt A): 177-185 (2017-03-30)



Arcourt A.; Gorham L.; Dhandapani R.; Prato V.; Taberner F.J.; Wende H.; Gangadharan V.; Birchmeier C.; Heppenstall P.A.; Lechner S.G.
Touch receptor-derived sensory information alleviates acute pain signaling and fine-tunes nociceptive reflex coordination
Neuron 93 (1): 179-193 (2017-01-04)



2016

Hernandez-Miranda L.R.; Mueller T.; Birchmeier C.
The dorsal spinal cord and hindbrain: from developmental mechanisms to functional circuits
Developmental Biology : (2016-10-11)



Esteves de Lima J.; Bonnin M.A.; Birchmeier C.; Duprez D.
Muscle contraction is required to maintain the pool of muscle progenitors via YAP and NOTCH during fetal myogenesis
eLife 5: e15593 (2016-08-24)



Bartus K.; Galino J.; James N.D.; Hernandez-Miranda L.R.; Dawes J.M.; Fricker F.R.; Garratt A.N.; McMahon S.B.; Ramer M.S.; Birchmeier C.; Bennett D.L.H.; Bradbury E.J.
Neuregulin-1 controls an endogenous repair mechanism after spinal cord injury
Brain 139 (Pt 5): 1394-1416 (2016-05)



Birchmeier C.; Bennett D.L.H.
Neuregulin/ErbB signaling in developmental myelin formation and nerve repair
Current Topics in Developmental Biology 116: 45-64 (2016)



2015

Jia S.; Wildner H.; Birchmeier C.
Insm1 controls the differentiation of pulmonary neuroendocrine cells by repressing Hes1
Developmental Biology 408 (1): 90-98 (2015-12-01)



Wiegreffe C.; Simon R.; Peschkes K.; Kling C.; Strehle M.; Cheng J.; Srivatsa S.; Liu P.; Jenkins N.A.; Copeland N.G.; Tarabykin V.; Britsch S.
Bcl11a (Ctip1) controls migration of cortical projection neurons through regulation of Sema3c
Neuron 87 (2): 311-325 (2015-07-15)



Hernandez-Miranda L.R.; Birchmeier C.
CO2 in the spotlight
eLife 4: e08086 (2015-05-13)



Jia S.; Ivanov A.; Blasevic D.; Mueller T.; Purfuerst B.; Sun W.; Chen W.; Poy M.N.; Rajewsky N.; Birchmeier C.
Insm1 cooperates with Neurod1 and Foxa2 to maintain mature pancreatic {beta}-cell function
EMBO Journal 34 (10): 1417-1433 (2015-05-12)



Sury M.D.; McShane E.; Hernandez-Miranda L.R.; Birchmeier C.; Selbach M.
Quantitative proteomics reveals dynamic interaction of c-Jun N-terminal kinase (JNK) with RNA transport granule proteins splicing factor proline- and glutamine-rich (Sfpq) and non-POU domain-containing octamer-binding protein (Nono) during neuronal differentiation
Molecular & Cellular Proteomics 14 (1): 50-65 (2015-01-01)



2014

Czajkowski M.T.; Rassek C.; Lenhard D.; Broehl D.; Birchmeier C.
Divergent and conserved roles of Dll1 signaling in development of craniofacial and trunk muscle
Developmental Biology 395 (2): 307-3016 (2014-11-15)



Loos M.; Mueller T.; Gouwenberg Y.; Wijnands R.; van der Loo R.J.; Birchmeier C.; Smit A.B.; Spijker S.
Neuregulin-3 in the mouse medial prefrontal cortex regulates impulsive action
Biological Psychiatry 76 (8): 648-655 (2014-10-15)



Marg A.; Escobar H.; Gloy S.; Kufeld M.; Zacher J.; Spuler A.; Birchmeier C.; Izsvak Z.; Spuler S.
Human satellite cells have regenerative capacity and are genetically manipulable
Journal of Clinical Investigation 124 (10): 4257-4265 (2014-10-01)



Simaite D.; Kofent J.; Gong M.; Rueschendorf F.; Jia S.; Arn P.; Bentler K.; Ellaway C.; Kuehnen P.; Hoffmann G.F.; Blau N.; Spagnoli F.M.; Huebner N.; Raile K.
Recessive mutations in PCBD1 cause a new type of early-onset diabetes
Diabetes 63 (10): 3557-3564 (2014-10)



Dyachuk V.; Furlan A.; Shahidi M.K.; Giovenco M.; Kaukua N.; Konstantinidou C.; Pachnis V.; Memic F.; Marklund U.; Mueller T.; Birchmeier C.; Fried K.; Ernfors P.; Adameyko I.
Parasympathetic neurons originate from nerve-associated peripheral glial progenitors
Science 345 (6192): 82-87 (2014-07-04)



Zalc A.; Hayashi S.; Aurade F.; Broehl D.; Chang T.; Mademtzoglou D.; Mourikis P.; Yao Z.; Cao Y.; Birchmeier C.; Relaix F.
Antagonistic regulation of p57(kip2) by Hes/Hey downstream of Notch signaling and muscle regulatory factors regulates skeletal muscle growth arrest
Development 141 (14): 2780-2790 (2014-07)



Ragancokova D.; Rocca E.; Oonk A.M.M.; Schulz H.; Rohde E.; Bednarsch J.; Feenstra I.; Pennings R.J.E.; Wende H.; Garratt A.N.
TSHZ1-dependent gene regulation is essential for olfactory bulb development and olfaction
Journal of Clinical Investigation 124 (3): 1214-1227 (2014-03-03)



Sheean M.E.; McShane E.; Cheret C.; Walcher J.; Mueller T.; Wulf-Goldenberg A.; Hoelper S.; Garratt A.N.; Krueger M.; Rajewsky K.; Meijer D.; Birchmeier W.; Lewin G.R.; Selbach M.; Birchmeier C.
Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination
Genes & Development 28 (3): 290-303 (2014-02-01)



2013

Welcker J.E.; Hernandez-Miranda L.R.; Paul F.E.; Jia S.; Ivanov A.; Selbach M.; Birchmeier C.
Insm1 controls development of pituitary endocrine cells and requires a SNAG domain for function and for recruitment of histone-modifying factors
Development 140 (24): 4947-4958 (2013-12)



Grigoryan T.; Stein S.; Qi J.; Wende H.; Garratt A.N.; Nave K.A.; Birchmeier C.; Birchmeier W.
Wnt/Rspondin/{beta}-catenin signals control axonal sorting and lineage progression in Schwann cell development
Proceedings of the National Academy of Sciences of the United States of America 110 (45): 18174-18179 (2013-11-05)



Sartori R.; Schirwis E.; Blaauw B.; Bortolanza S.; Zhao J.; Enzo E.; Stantzou A.; Mouisel E.; Toniolo L.; Ferry A.; Stricker S.; Goldberg A.L.; Dupont S.; Piccolo S.; Amthor H.; Sandri M.
BMP signaling controls muscle mass
Nature Genetics 45 (11): 1309-1318 (2013-11)



Xu Y.; Lopes C.; Wende H.; Guo Z.; Cheng L.; Birchmeier C.; Ma Q.
Ontogeny of excitatory spinal neurons processing distinct somatic sensory modalities
Journal of Neuroscience 33 (37): 14738-14748 (2013-09-11)



Ebel P.; Vom Dorp K.; Petrasch-Parwez E.; Zlomuzica A.; Kinugawa K.; Mariani J.; Minich D.; Ginkel C.; Welcker J.; Degen J.; Eckhardt M.; Dere E.; Doermann P.; Willecke K.
Inactivation of ceramide synthase 6 in mice results in an altered sphingolipid metabolism and behavioral abnormalities
Journal of Biological Chemistry 288 (29): 21433-21447 (2013-07-19)



Cheret C.; Willem M.; Fricker F.R.; Wende H.; Wulf-Goldenberg A.; Tahirovic S.; Nave K.A.; Saftig P.; Haass C.; Garratt A.N.; Bennett D.L.; Birchmeier C.
Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles
EMBO Journal 32 (14): 2015-2028 (2013-07-17)



Fricker F.R.; Antunes-Martins A.; Galino J.; Paramsothy R.; La Russa F.; Perkins J.; Goldberg R.; Brelstaff J.; Zhu N.; McMahon S.B.; Orengo C.; Garratt A.N.; Birchmeier C.; Bennett D.L.
Axonal neuregulin 1 is a rate limiting but not essential factor for nerve remyelination
Brain 136 (Pt 7): 2279-2297 (2013-07)



Wildner H.; Das Gupta R.; Broehl D.; Heppenstall P.A.; Zeilhofer H.U.; Birchmeier C.
Genome-wide expression analysis of ptf1a- and ascl1-deficient mice reveals new markers for distinct dorsal horn interneuron populations contributing to nociceptive reflex plasticity
Journal of Neuroscience 33 (17): 7299-7307 (2013-04-24)



Sun H.; Knippenberg S.; Thau N.; Ragancokova D.; Koerner S.; Huang D.; Dengler R.; Doehler K.; Petri S.
Therapeutic potential of N-acetyl-glucagon-like peptide-1 in primary motor neuron cultures derived from non-transgenic and SOD1-G93A ALS mice
Cellular and Molecular Neurobiology 33 (3): 347-357 (2013-04)



2012

Wende H.; Lechner S.G.; Birchmeier C.
The transcription factor c-Maf in sensory neuron development
Transcription 3 (6): 285-289 (2012-11)



Ciofani M.; Madar A.; Galan C.; Sellars M.; Mace K.; Pauli F.; Agarwal A.; Huang W.; Parkurst C.N.; Muratet M.; Newberry K.M.; Meadows S.; Greenfield A.; Yang Y.; Jain P.; Kirigin F.K.; Birchmeier C.; Wagner E.F.; Murphy K.M.; Myers R.M.; Bonneau R.; Littman D.R.
A validated regulatory network for Th17 cell specification
Cell 151 (2): 289-303 (2012-10-12)



Broehl D.; Vasyutina E.; Czajkowski M.T.; Griger J.; Rassek C.; Rahn H.P.; Purfuerst B.; Wende H.; Birchmeier C.
Colonization of the satellite cell niche by skeletal muscle progenitor cells depends on notch signals
Developmental Cell 23 (3): 469-481 (2012-09-11)



Baek J.H.; Birchmeier C.; Zenke M.; Hieronymus T.
The HGF receptor/Met tyrosine kinase is a key regulator of dendritic cell migration in skin immunity
Journal of Immunology 189 (4): 1699-1707 (2012-08-15)



Cadot B.; Gache V.; Vasyutina E.; Falcone S.; Birchmeier C.; Gomes E.R.
Nuclear movement during myotube formation is microtubule and dynein dependent and is regulated by Cdc42, Par6 and Par3
EMBO Reports 13 (8): 741-749 (2012-08-01)



Lahlou H.; Mueller T.; Sanguin-Gendreau V.; Birchmeier C.; Muller W.J.
Uncoupling of PI3K from ErbB3 impairs mammary gland development but does not impact on ErbB2-induced mammary tumorigenesis
Cancer Research 72 (12): 3080-3090 (2012-06-15)



John A.; Brylka H.; Wiegreffe C.; Simon R.; Liu P.; Juettner R.; Crenshaw E.B.; Luyten F.P.; Jenkins N.A.; Copeland N.G.; Birchmeier C.; Britsch S.
Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development
Development 139 (10): 1831-1841 (2012-05-15)



Simon R.; Brylka H.; Schwegler H.; Venkataramanappa S.; Andratschke J.; Wiegreffe C.; Liu P.; Fuchs E.; Jenkins N.A.; Copeland N.G.; Birchmeier C.; Britsch S.
A dual function of Bcl11b/Ctip2 in hippocampal neurogenesis
EMBO Journal 31 (13): 2922-2936 (2012-05-15)



Wende H.; Lechner S.G.; Cheret C.; Bourane S.; Kolanczyk M.E.; Pattyn A.; Reuter K.; Munier F.L.; Carroll P.; Lewin G.R.; Birchmeier C.
The transcription factor c-Maf controls touch receptor development and function
Science 335 (6074): 1373-1376 (2012-03-16)



Gherardi E.; Birchmeier W.; Birchmeier C.; Woude G.V.
Targeting MET in cancer: rationale and progress
Nature Reviews Cancer 12 (2): 89-103 (2012-02)



Fleck D.; Garratt A.N.; Haass C.; Willem M.
BACE1 dependent neuregulin processing: review
Current Alzheimer Research 9 (2): 178-183 (2012-02)



Adameyko I.; Lallemend F.; Furlan A.; Zinin N.; Aranda S.; Kitambi S.S.; Blanchart A.; Favaro R.; Nicolis S.; Luebke M.; Mueller T.; Birchmeier C.; Suter U.; Zaitoun I.; Takahashi Y.; Ernfors P.
Sox2 and Mitf cross-regulatory interactions consolidate progenitor and melanocyte lineages in the cranial neural crest
Development 139 (2): 397-410 (2012-01-15)



2011

D'Autreaux F.; Coppola E.; Hirsch M.R.; Birchmeier C.; Brunet J.F.
Homeoprotein Phox2b commands a somatic-to-visceral switch in cranial sensory pathways
Proceedings of the National Academy of Sciences of the United States of America 108 (50): 20018-20023 (2011-12-13)



Van Ho A.T.; Hayashi S.; Broehl D.; Aurade F.; Rattenbach R.; Relaix F.
Neural crest cell lineage restricts skeletal muscle progenitor cell differentiation through Neuregulin1-ErbB3 signaling
Developmental Cell 21 (2): 273-287 (2011-08-16)



Fricker F.R.; Lago N.; Balarajah S.; Tsantoulas C.; Tanna S.; Zhu N.; Fageiry S.K.; Jenkins M.; Garratt A.N.; Birchmeier C.; Bennett D.L.
Axonally derived neuregulin-1 is required for remyelination and regeneration after nerve injury in adulthood
Journal of Neuroscience 31 (9): 3225-3233 (2011-03-02)



Birchmeier C.
Preface
Current Topics in Developmental Biology 97: xi-xii (2011)



2010

Newbern J.; Birchmeier C.
Nrg1/ErbB signaling networks in Schwann cell development and myelination
Seminars in Cell & Developmental Biology 21 (9): 922-988 (2010-12)



Birchmeier C.
Development and more
Seminars in Cell & Developmental Biology 21 (8): 812-813 (2010-10)



Lai D.; Forrai A.; Liu X.; Wolstein O.; Michalicek J.; Ahmed I.; Garratt A.N.; Birchmeier C.; Zhou M.; Hartley L.; Robb L.; Feneley M.P.; Fatkin D.; Harvey R.P.
Neuregulin 1 sustains the gene regulatory network in both trabecular and nontrabecular myocardium
Circulation Research 107 (6): 715-727 (2010-09-17)



Grossmann K.S.; Rosario M.; Birchmeier C.; Birchmeier W.
The tyrosine phosphatase Shp2 in development and cancer
Advances in Cancer Research 106: 53-89 (2010)



2009

Birchmeier C.
A fresh breeze from the ivory tower
Current Opinion in Cell Biology 21 (6): 725-726 (2009-12)



Dubreuil V.; Thoby-Brisson M.; Rallu M.; Persson K.; Pattyn A.; Birchmeier C.; Brunet J.F.; Fortin G.; Goridis C.
Defective respiratory rhythmogenesis and loss of central chemosensitivity in Phox2b mutants targeting retrotrapezoid nucleus neurons
Journal of Neuroscience 29 (47): 14836-14846 (2009-11-25)



Adameyko I.; Lallemend F.; Aquino J.B.; Pereira J.A.; Topilko P.; Mueller T.; Fritz N.; Beljajeva A.; Mochii M.; Liste I.; Usoskin D.; Suter U.; Birchmeier C.; Ernfors P.
Schwann cell precursors from nerve innervation are a cellular origin of melanocytes in skin
Cell 139 (2): 366-379 (2009-10-16)



Grossmann K.S.; Wende H.; Paul F.E.; Cheret C.; Garratt A.N.; Zurborg S.; Feinberg K.; Besser D.; Schulz H.; Peles E.; Selbach M.; Birchmeier W.; Birchmeier C.
The tyrosine phosphatase Shp2 (PTPN11) directs neuregulin-1/ErbB signaling throughout schwann cell development
Proceedings of the National Academy of Sciences of the United States of America 106 (39): 16704-16709 (2009-09-29)



Grossmann K.S.; Wende H.; Paul F.E.; Cheret C.; Garratt A.N.; Zurborg S.; Feinberg K.; Besser D.; Schulz H.; Peles E.; Selbach M.; Birchmeier W.; Birchmeier C.
The tyrosine phosphatase Shp2 (PTPN11) directs neuregulin-1/ErbB signaling throughout schwann cell development
Proceedings of the National Academy of Sciences of the United States of America 106 (39): 16704-16709 (2009-09-29)



Trimbuch T.; Beed P.; Vogt J.; Schuchmann S.; Maier N.; Kintscher M.; Breustedt J.; Schuelke M.; Streu N.; Kieselmann O.; Brunk I.; Laube G.; Strauss U.; Battefeld A.; Wende H.; Birchmeier C.; Wiese S.; Sendtner M.; Kawabe H.; Kishimoto-Suga M.; Brose N.; Baumgart J.; Geist B.; Aoki J.; Savaskan N.E.; Braeuer A.U.; Chun J.; Ninnemann O.; Schmitz D.; Nitsch R.
Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling
Cell 138 (6): 1222-12235 (2009-09-18)



Giebeler A.; Boekschoten M.V.; Klein C.; Borowiak M.; Birchmeier C.; Gassler N.; Wasmuth H.E.; Mueller M.; Trautwein C.; Streetz K.L.
c-Met confers protection against chronic liver tissue damage and fibrosis progression after bile-duct-ligation in mice
Gastroenterology 137 (1): 297-308 (2009-07)



Jacob J.; Storm R.; Castro D.S.; Milton C.; Pla P.; Guillemot F.; Birchmeier C.; Briscoe J.
Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain
Development 136 (14): 2477-2485 (2009-07)



Fricker F.R.; Zhu N.; Tsantoulas C.; Abrahamsen B.; Nassar M.A.; Thakur M.; Garratt A.N.; Birchmeier C.; McMahon S.B.; Wood J.N.; Bennett D.L.
Sensory axon-derived neuregulin-1 is required for axoglial signaling and normal sensory function but not for long-term axon maintenance
Journal of Neuroscience 29 (24): 7667-7678 (2009-06-17)



Vasyutina E.; Martarelli B.; Brakebusch C.; Wende H.; Birchmeier C.
The small G-proteins Rac1 and Cdc42 are essential for myoblast fusion in the mouse
Proceedings of the National Academy of Sciences of the United States of America 106 (22): 8935-8940 (2009-06-02)



Marx-Stoelting P.; Borowiak M.; Knorpp T.; Birchmeier C.; Buchmann A.; Schwarz M.
Hepatocarcinogenesis in mice with a conditional knockout of the hepatocyte growth factor receptor c-Met
International Journal of Cancer 124 (8): 1767-1772 (2009-04-15)



Freese C.; Garratt A.N.; Fahrenholz F.; Endres K.
The effects of alpha-secretase ADAM10 on the proteolysis of neuregulin-1
FEBS Journal 276 (6): 1568-1580 (2009-03)



Birchmeier C.
ErbB receptors and the development of the nervous system
Experimental Cell Research 315 (4): 611-618 (2009-02-15)



Storm R.; Cholewa-Waclaw J.; Reuter K.; Broehl D.; Sieber M.; Treier M.; Mueller T.; Birchmeier C.
The bHLH transcription factor Olig3 marks the dorsal neuroepithelium of the hindbrain and is essential for the development of brainstem nuclei
Development 136 (2): 295-305 (2009-01)



2008

Birchmeier C.; Nave K.A.
Neuregulin-1, a key axonal signal that drives Schwann cell growth and differentiation
Glia 56 (14): 1491-1497 (2008-11-01)



Broehl D.; Strehle M.; Wende H.; Hori K.; Bormuth I.; Nave K.A.; Mueller T.; Birchmeier C.
A transcriptional network coordinately determines transmitter and peptidergic fate in the dorsal spinal cord
Developmental Biology 322 (2): 381-393 (2008-10-15)



Farkas L.M.; Haffner C.; Giger T.; Khaitovich P.; Nowick K.; Birchmeier C.; Paeaebo S.; Huttner W.B.
Insulinoma-associated 1 has a panneurogenic role and promotes the generation and expansion of Basal progenitors in the developing mouse neocortex
Neuron 60 (1): 40-55 (2008-10-09)



Caubit X.; Lye C.M.; Martin E.; Core N.; Long D.A.; Vola C.; Jenkins D.; Garratt A.N.; Skaer H.; Woolf A.S.; Fasano L.
Teashirt 3 is necessary for ureteral smooth muscle differentiation downstream of SHH and BMP4
Development 135 (19): 3301-3310 (2008-10)



Caubit X.; Lye C.M.; Martin E.; Core N.; Long D.A.; Vola C.; Jenkins D.; Garratt A.N.; Skaer H.; Woolf A.S.; Fasano L.
Teashirt 3 is necessary for ureteral smooth muscle differentiation downstream of SHH and BMP4
Development 135 (19): 3301-3310 (2008-10)



Brinkmann B.G.; Agarwal A.; Sereda M.W.; Garratt A.N.; Mueller T.; Wende H.; Stassart R.M.; Nawaz S.; Humml C.; Velanac V.; Radyushkin K.; Goebbels S.; Fischer T.M.; Franklin R.J.; Lai C.; Ehrenreich H.; Birchmeier C.; Schwab M.H.; Nave K.A.
Neuregulin-1/ErbB signaling serves distinct functions in myelination of the peripheral and central nervous system
Neuron 59 (4): 581-595 (2008-08-28)



Wildner H.; Gierl M.S.; Strehle M.; Pla P.; Birchmeier C.
Insm1 (IA-1) is a crucial component of the transcriptional network that controls differentiation of the sympatho-adrenal lineage
Development 135 (3): 473-81 (2008-02)



Hori K.; Cholewa-Waclaw J.; Nakada Y.; Glasgow S.M.; Masui T.; Henke R.M.; Wildner H.; Martarelli B.; Beres T.M.; Epstein J.A.; Magnuson M.A.; Macdonald R.J.; Birchmeier C.; Johnson J.E.
A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling
Genes & Development 22 (2): 166-178 (2008-01-15)



2007

Milenkovic N.; Frahm C.; Gassmann M.; Griffel C.; Erdmann B.; Birchmeier C.; Lewin G.R.; Garratt A.N.
Nociceptive tuning by stem cell factor/c-Kit signaling
Neuron 56 (5): 893-906 (2007-12-06)



Hesse M.; Grund C.; Herrmann H.; Broehl D.; Franz T.; Omary M.B.; Magin T.M.
A mutation of keratin 18 within the coil 1A consensus motif causes widespread keratin aggregation but cell type-restricted lethality in mice
Experimental Cell Research 313 (14): 3127-3140 (2007-08-15)



Potzner M.R.; Griffel C.; Luetjen-Drecoll E.; Boesl M.R.; Wegner M.; Sock E.
Prolonged Sox4 expression in oligodendrocytes interferes with normal myelination in the central nervous system
Molecular and Cellular Biology 27 (15): 5316-5326 (2007-08)



Vasyutina E.; Lenhard D.C.; Birchmeier C.
Notch function in myogenesis
Cell Cycle 6 (12): 1451-1454 (2007-06-15)



Sieber M.A.; Storm R.; Martinez-de-la-Torre M.; Mueller T.; Wende H.; Reuter K.; Vasyutina E.; Birchmeier C.
Lbx1 acts as a selector gene in the fate determination of somatosensory and viscerosensory relay neurons in the hindbrain
Journal of Neuroscience 27 (18): 4902-4909 (2007-05-02)



Chmielowiec J.; Borowiak M.; Morkel M.; Stradal T.; Munz B.; Werner S.; Wehland J.; Birchmeier C.; Birchmeier W.
c-Met is essential for wound healing in the skin
Journal of Cell Biology 177 (1): 151-162 (2007-04-09)



Vasyutina E.; Lenhard D.C.; Wende H.; Erdmann B.; Epstein J.A.; Birchmeier C.
RBP-J (Rbpsuh) is essential to maintain muscle progenitor cells and to generate satellite cells
Proceedings of the National Academy of Sciences of the United States of America 104 (11): 4443-4448 (2007-03-13)



Grego-Bessa J.; Luna-Zurita L.; del Monte G.; Bolos V.; Melgar P.; Arandilla A.; Garratt A.N.; Zang H.; Mukouyama Y.S.; Chen H.; Shou W.; Ballestar E.; Esteller M.; Rojas A.; Perez-Pomares J.M.; de la Pompa J.L.
Notch signaling is essential for ventricular chamber development
Developmental Cell 12 (3): 415-429 (2007-03)



Zechner D.; Muller T.; Wende H.; Walther I.; Taketo M.M.; Crenshaw E.B.; Treier M.; Birchmeier W.; Birchmeier C.
Bmp and Wnt/beta-catenin signals control expression of the transcription factor Olig3 and the specification of spinal cord neurons
Developmental Biology 303 (1): 181-190 (2007-03-01)



Grego-Bessa J.; Luna-Zurita L.; del Monte G.; Bolos V.; Melgar P.; Arandilla A.; Garratt A.N.; Zang H.; Mukouyama Y.S.; Chen H.; Shou W.; Ballestar E.; Esteller M.; Rojas A.; Perez-Pomares J.M.; de la Pompa J.L.
Notch signaling is essential for ventricular chamber development
Developmental Cell 12 (3): 415-429 (2007-03)



Wulczyn F.G.; Smirnova L.; Rybak A.; Brandt C.; Kwidzinski E.; Ninnemann O.; Strehle M.; Seiler A.; Schumacher S.; Nitsch R.
Post-transcriptional regulation of the let-7 microRNA during neural cell specification
FASEB Journal 21 (2): 415-426 (2007-02)



2006

Vasyutina E.; Birchmeier C.
The development of migrating muscle precursor cells
Anatomy and Embryology 211 (Suppl.): S37-S41 (2006-12)



Willem M.; Garratt A.N.; Novak B.; Citron M.; Kaufmann S.; Rittger A.; Destrooper B.; Saftig P.; Birchmeier C.; Haass C.
Control of peripheral nerve myelination by the {beta}-secretase BACE1
Science 314 (5799): 664-666 (2006-10-27)



Willem M.; Garratt A.N.; Novak B.; Citron M.; Kaufmann S.; Rittger A.; Destrooper B.; Saftig P.; Birchmeier C.; Haass C.
Control of peripheral nerve myelination by the {beta}-secretase BACE1
Science 314 (5799): 664-666 (2006-10-27)



Gierl M.S.; Karoulias N.; Wende H.; Strehle M.; Birchmeier C.
The Zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells
Genes & Development 20 (17): 2465-2478 (2006-09-01)



Garratt A.N.
"To erb-B or not to erb-B..." Neuregulin-1/ErbB signaling in heart development and function
Journal of Molecular and Cellular Cardiology 41 (2): 215-218 (2006-08)



Garratt A.N.
"To erb-B or not to erb-B..." Neuregulin-1/ErbB signaling in heart development and function
Journal of Molecular and Cellular Cardiology 41 (2): 215-218 (2006-08)



Wildner H.; Mueller T.; Cho S.H.; Broehl D.; Cepko C.L.; Guillemot F.; Birchmeier C.
dILA neurons in the dorsal spinal cord are the product of terminal and non-terminal asymmetric progenitor cell divisions, and require Mash1 for their development
Development 133 (11): 2105-2113 (2006-06-01)



Lopez-Bendito G.; Cautinat A.; Sanchez J.A.; Bielle F.; Flames N.; Garratt A.N.; Talmage D.A.; Role L.W.; Charnay P.; Marin O.; Garel S.
Tangential neuronal migration controls axon guidance: a role for neuregulin-1 in thalamocortical axon navigation
Cell 125 (1): 127-142 (2006-04-07)



Lopez-Bendito G.; Cautinat A.; Sanchez J.A.; Bielle F.; Flames N.; Garratt A.N.; Talmage D.A.; Role L.W.; Charnay P.; Marin O.; Garel S.
Tangential neuronal migration controls axon guidance: a role for neuregulin-1 in thalamocortical axon navigation
Cell 125 (1): 127-142 (2006-04-07)



Atanasoski S.; Scherer S.S.; Sirkowski E.; Leone D.; Garratt A.N.; Birchmeier C.; Suter U.
ErbB2 signaling in Schwann cells is mostly dispensable for maintenance of myelinated peripheral nerves and proliferation of adult Schwann cells after injury
Journal of Neuroscience 26 (7): 2124-2131 (2006-02-15)



Atanasoski S.; Scherer S.S.; Sirkowski E.; Leone D.; Garratt A.N.; Birchmeier C.; Suter U.
ErbB2 signaling in Schwann cells is mostly dispensable for maintenance of myelinated peripheral nerves and proliferation of adult Schwann cells after injury
Journal of Neuroscience 26 (7): 2124-2131 (2006-02-15)



Mueller T.
Neural development
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2 : 1258-1266 (2006)



Britsch S.
Transgenic and knock-out animals
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2 : 1900-1903 (2006)



2005

John A.; Wildner H.; Britsch S.
The homeodomain transcription factor Gbx1 identifies a subpopulation of late-born GABAergic interneurons in the developing dorsal spinal cord
Developmental Dynamics 234 (3): 767-771 (2005-09-28)



Vasyutina E.; Stebler J.; Brand-Saberi B.; Schulz S.; Raz E.; Birchmeier C.
CXCR4 and Gab1 cooperate to control the development of migrating muscle progenitor cells
Genes & Development 19 (18): 2187-2198 (2005-09-15)



Humphries J.D.; Schofield N.R.; Mostafavi-Pour Z.; Green L.J.; Garratt A.N.; Mould A.P.; Humphries M.J.
Dual functionality of the anti-beta1 integrin antibody, 12G10, exemplifies agonistic signalling from the ligand binding pocket of integrin adhesion receptors
Journal of Biological Chemistry 280 (11): 10234-10243 (2005-03-18)



Humphries J.D.; Schofield N.R.; Mostafavi-Pour Z.; Green L.J.; Garratt A.N.; Mould A.P.; Humphries M.J.
Dual functionality of the anti-beta1 integrin antibody, 12G10, exemplifies agonistic signalling from the ligand binding pocket of integrin adhesion receptors
Journal of Biological Chemistry 280 (11): 10234-10243 (2005-03-18)



Muller T.; Anlag K.; Wildner H.; Britsch S.; Treier M.; Birchmeier C.
The bHLH factor Olig3 coordinates the specification of dorsal neurons in the spinal cord
Genes & Development 19 (6): 733-743 (2005-01-01)



Pohlers M.; Truss M.; Frede U.; Scholz A.; Strehle M.; Kuban R.J.; Hoffmann B.; Morkel M.; Birchmeier C.; Hagemeier C.
A role for E2F6 in the restriction of male-germ-cell-specific gene expression
Current Biology 15 (11): 1051-1057 (2005-01-01)



2004

Graveel C.; Su Y.; Koeman J.; Wang L.M.; Tessarollo L.; Fiscella M.; Birchmeier C.; Swiatek P.; Bronson R.; Vande Woude G.F.
Activating Met mutations produce unique tumor profiles in mice with selective duplication of the mutant allele
Proceedings of the National Academy of Sciences of the United States of America 101 (49): 17198-17203 (2004-12-07)



Flames N.; Long J.E.; Garratt A.N.; Fischer T.M.; Gassmann M.; Birchmeier C.; Lai C.; Rubenstein J.L.; Marin O.
Short- and long-range attraction of cortical GABAergic interneurons by neuregulin-1
Neuron 44 (2): 251-261 (2004-10-14)



Flames N.; Long J.E.; Garratt A.N.; Fischer T.M.; Gassmann M.; Birchmeier C.; Lai C.; Rubenstein J.L.; Marin O.
Short- and long-range attraction of cortical GABAergic interneurons by neuregulin-1
Neuron 44 (2): 251-261 (2004-10-14)



Michailov G.V.; Sereda M.W.; Brinkmann B.G.; Fischer T.M.; Haug B.; Birchmeier C.; Role L.; Lai C.; Schwab M.H.; Nave K.A.
Axonal neuregulin-1 regulates myelin sheath thickness
Science 304 (5671): 700-703 (2004-04-30)



Borowiak M.; Garratt A.N.; Wuestefeld T.; Strehle M.; Trautwein C.; Birchmeier C.
Met provides essential signals for liver regeneration
Proceedings of the National Academy of Sciences of the United States of America 101 (29): 10608-10613 (2004-01-01)



Borowiak M.; Garratt A.N.; Wuestefeld T.; Strehle M.; Trautwein C.; Birchmeier C.
Met provides essential signals for liver regeneration
Proceedings of the National Academy of Sciences of the United States of America 101 (29): 10608-10613 (2004-01-01)



2003

Birchmeier C.; Birchmeier W.; Gherardi E.; Vande Woude G.F.
Met, metastasis, motility and more
Nature Reviews Molecular Cell Biology 4 (12): 915-925 (2003-12)



Zechner D.; Fujita Y.; Huelsken J.; Mueller T.; Walther I.; Taketo M.M.; Crenshaw E.B.; Birchmeier W.; Birchmeier C.
beta-catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system
Developmental Biology 258 (2): 406-418 (2003-06-15)



Garratt A.N.; Ozcelik C.; Birchmeier C.
ErbB2 pathways in heart and neural diseases
Trends in Cardiovascular Medicine 13 (2): 80-86 (2003-02)



Garratt A.N.; Ozcelik C.; Birchmeier C.
ErbB2 pathways in heart and neural diseases
Trends in Cardiovascular Medicine 13 (2): 80-86 (2003-02)



Young H.M.; Bergner A.J.; Mueller T.
Acquisition of neuronal and glial markers by neural crest-derived cells in the mouse intestine
Journal of Comparative Neurology 456 (1): 1-11 (2003-01-27)



Britsch S.; Strehle M.; Birchmeier C.
Tiermodelle in der biomedizinischen Forschung
Grundlagen der Molekularen Medizin : 299-339 (2003-01-01)



2002

Hippenmeyer S.; Shneider N.A.; Birchmeier C.; Burden S.J.; Jessell T.M.; Arber S.
A role for Neuregulin1 signaling in muscle spindle differentiation
Neuron 36 (6): 1035-1049 (2002-12-19)



Oezcelik C.; Erdmann B.; Pilz B.; Wettschureck N.; Britsch S.; Huebner N.; Chien K.R.; Birchmeier C.; Garratt A.N.
Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy
Proceedings of the National Academy of Sciences of the United States of America 99 (13): 8880-8885 (2002-06-25)



Oezcelik C.; Erdmann B.; Pilz B.; Wettschureck N.; Britsch S.; Huebner N.; Chien K.R.; Birchmeier C.; Garratt A.N.
Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy
Proceedings of the National Academy of Sciences of the United States of America 99 (13): 8880-8885 (2002-06-25)



Mukouyama Y.; Shin D.; Britsch S.; Taniguchi M.; Anderson D.J.
Sensory nerves determine the pattern of arterial differentiation and blood vessel branching in the skin
Cell 109 (6): 693-705 (2002-06-14)



Schneider J.W.; Chang A.Y.; Garratt A.
Trastuzumab cardiotoxicity: Speculations regarding pathophysiology and targets for further study
Seminars in Oncology 29 (3): 22-28 (2002-06)



Schneider J.W.; Chang A.Y.; Garratt A.
Trastuzumab cardiotoxicity: Speculations regarding pathophysiology and targets for further study
Seminars in Oncology 29 (3): 22-28 (2002-06)



Mueller T.; Brohmann H.; Pierani A.; Heppenstall P.A.; Lewin G.R.; Jessell T.M.; Birchmeier C.
The homeodomain factor Lbx1 distinguishes two major programs of neuronal differentiation in the dorsal spinal cord
Neuron 34 (4): 551-562 (2002-05-16)



Li L.; Cleary S.; Mandarano M.A.; Long W.W.; Birchmeier C.; Jones F.E.
The breast proto-oncogene, HRGalpha regulates epithelial proliferation and lobuloalveolar development in the mouse mammary gland
Oncogene 21: 4900-4907 (2002-01-01)



2001

Birchmeier C.; Treier M.
Genomics boosts mouse molecular genetics
Trends in Genetics 17 (12): 691-692 (2001-12-01)



Keilhack H.; Mueller M.; Boehmer S.A.; Frank C.; Weidner K.M.; Birchmeier W.; Ligensa T.; Berndt A.; Kosmehl H.; Gunther B.; Mueller T.; Birchmeier C.; Boehmer F.D.
Negative regulation of Ros receptor tyrosine kinase signaling: An epithelial function of the SH2 domain protein tyrosine phosphatase SHP-1
Journal of Cell Biology 152 (2): 325-334 (2001-01-22)



Britsch S.; Goerich D.E.; Riethmacher D.; Peirano R.I.; Rossner M.; Nave K.A.; Birchmeier C.; Wegner M.
The transcription factor Sox10 is a key regulator of peripheral glial development
Genes & Development 15 (1): 66-78 (2001-01-01)



Yang X.; Arber S.; William C.; Li L.; Tanabe Y.; Jessell T.M.; Birchmeier C.; Burden S.J.
Patterning of muscle acetylcholine receptor gene expression in the absence of motor innervation
Neuron 30 (2): 399-410 (2001-01-01)



2000

Birchmeier C.; Brohmann H.
Genes that control the development of migrating muscle precursor cells
Current Opinion in Cell Biology 12 (6): 725-730 (2000-12-01)



Rosenthal N.; Birchmeier C.
Cell differentiation
Current Opinion in Cell Biology 12: 717-718 (2000-12-01)



Garratt A.N.; Britsch S.; Birchmeier C.
Neuregulin, a factor with many functions in the life of schwann cell
BioEssays 22 (11): 987-996 (2000-11)



Smits R.; Ruiz P.; Diaz-Cano S.; Luz A.; Jagmohan-Changur S.; Breukel C.; Birchmeier C.; Birchmeier W.; Fodde R.
E-cadherin and adenomatous polyposis coli mutations are synergistic in intestinal tumor initiation in mice
Gastroenterology 119 (4): 1045-1053 (2000-10-01)



Sachs M.; Brohmann H.; Zechner D.; Mueller T.; Huelsken J.; Walther I.; Schaeper U.; Birchmeier C.; Birchmeier W.
Essential role of Gab1 for signaling by the c-Met receptor in vivo
Journal of Cell Biology 150 (6): 1375-1384 (2000-09-18)



Caton A.; Hacker A.; Naeem A.; Livet J.; Maina F.; Bladt F.; Klein R.; Birchmeier C.; Guthrie S.
The branchial arches and HGF are growth-promoting and chemoattractant for cranial motor axons
Development 127 (8): 1751-1766 (2000-04-01)



Garratt A.N.; Voiculescu O.; Topilko P.; Charnay P.; Birchmeier C.
A dual role of erbB2 in myelination and in expansion of the Schwann cell precursor pool
Journal of Cell Biology 148 (5): 1035-1046 (2000-03-06)



Garratt A.N.; Voiculescu O.; Topilko P.; Charnay P.; Birchmeier C.
A dual role of erbB2 in myelination and in expansion of the Schwann cell precursor pool
Journal of Cell Biology 148 (5): 1035-1046 (2000-03-06)



Huelsken J.; Vogel R.; Brinkmann V.; Erdmann B.; Birchmeier C.; Birchmeier W.
Requirement for beta-catenin in anterior-posterior axis formation in mice
Journal of Cell Biology 148 (3): 567-578 (2000-02-07)



Brohmann H.; Jagla K.; Birchmeier C.
The role of Lbx1 in migration of muscle precursor cells
Development 127 (2): 437-445 (2000-01-01)



1999

Gaio U.; Schweickert A.; Fischer A.; Garratt A.N.; Mueller T.; Oezcelik C.; Lankes W.; Strehle M.; Britsch S.; Blum M.; Birchmeier C.
A role of the cryptic gene in the correct establishment of the left-right axis
Current Biology 9 (22): 1339-1342 (1999-11-18)



Woldeyesus M.T.; Britsch S.; Riethmacher D.; Xu L.; Sonnenberg-Riethmacher E.; Abou-Rebyeh F.; Harvey R.; Caroni P.; Birchmeier C.
Peripheral nervous system defects in erbB2 mutants following genetic rescue of heart development
Genes & Development 13: 2538-2548 (1999-10-01)



Kotlyarov A.; Neininger A.; Schubert C.; Eckert R.; Birchmeier C.; Volk H.D.; Gaestel M.
MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis
Nature Cell Biology 1: 94-97 (1999-06-01)



Dietrich S.; Abou-Rebyeh F.; Brohmann H.; Bladt F.; Yamaai T.; Lumsden A.; Brand-Saberi B.; Birchmeier C.
The role of SF/HGF and c-Met in the development of skeletal muscle
Development 126: 1621-1629 (1999-04-01)



Birchmeier W.; Birchmeier C.
Epithelial Morphogenesis in Development and Disease
: (1999-01-01)



Birchmeier W.; Birchmeier C.; Brinkmann V.; Niemann C.
10. Tyrosine kinase receptors as driving forces for growth, motility and differentiation of epithelial cells
Epithelial Morphogenesis in Development and Disease : 217-231 (1999-01-01)



1998

Birchmeier C.; Gherardi E.
Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase
Trends in Cell Biology 8 (10): 404-410 (1998-10-01)



Hartmann G.; Prospero T.; Brinkmann V.; Ozcelik O.; Winter G.; Hepple J.; Batley S.; Bladt F.; Sachs M.; Birchmeier C.; Birchmeier W.; Gherardi E.
Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans, decreased clearance and enhanced activity in vivo
Current Biology 8 (3): 125-134 (1998-01-29)



Walther T.; Balschun D.; Voigt J.P.; Fink H.; Zuschratter W.; Birchmeier C.; Ganten D.; Bader M.
Sustained long-term potentiation and anxiety in mice lacking the Mas protooncogene
Journal of Biological Chemistry 273: 11867-11873 (1998-01-01)



Britsch S.; Li L.; Kirchhoff S.; Theuring F.; Brinkmann V.; Birchmeier C.; Riethmacher D.
The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system
Genes & Development 12: 1825-1836 (1998-01-01)



1997

Ebens A.; Brose K.; Leonardo E.D.; Hanson M.G.; Bladt F.; Birchmeier C.; Barres B.A.; Tessierlavigne M.
Hepatocyte growth factor/scatter factor is an axonal chemoattractant and a neurotrophic factor for spinal motor neurons
Neuron 17 (6): 1157-1172 (1997-12-01)



Riethmacher D.; Sonnenberg-Riethmacher E.; Brinkmann V.; Yamaai T.; Lewin G.R.; Birchmeier C.
Severe neuropathies in mice with targeted mutations in the ErbB3 receptor
Nature 389 (6652): 725-730 (1997-10-16)



Meyer D.; Yamaai T.; Garratt A.; Riethmacher-Sonnenberg E.; Kane D.; Theill L.E.; Birchmeier C.
Isoform specific expression and function of neuregulin
Development 124 (18): 3575-3586 (1997-09)



Kjelsberg C.; Sakurai H.; Spokes K.; Birchmeier C.; Drummond I.; Nigam S.; Cantley L.G.
Met -/- kidneys express epithelial cells that chemotax and form tubules in response to EGF receptor ligands
American Journal of Physiology Renal Physiology 272: F222-F228 (1997-01-01)



Birchmeier C.; Riethmacher D.; Brinkmann V.
Morphogenesis of epithelial cells
Adhesion Molecules in Health and Disease : 205-222 (1997-01-01)



Birchmeier C.; Bladt F.; Britsch S.
Tiermodelle in der biomedizinischen Forschung
Molekular- und Zellbiologische Grundlagen : 338-358 (1997-01-01)



Birchmeier C.; Bladt F.; Yamaai T.
The functions of HGF/SF and its receptor, the c-Met tyrosine kinase, in mammalian development
Ciba Foundation Symposia 212: 169-177, discussion 177-82. (1997-01-01)



1996

Ruiz P.; Brinkmann V.; Ledermann B.; Behrend M.; Grund C.; Thalhammer C.; Vogel F.; Birchmeier C.; Guenthert U.; Franke W.W.; Birchmeier W.
Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart
Journal of Cell Biology 135 (1): 215-225 (1996-10)



Birchmeier C.; Birchmeier W.; Brand-Saberi B.
Epithelial-mesenchymal transitions in cancer progression
Acta Anatomica 156: 217-226 (1996-01-01)



Birchmeier W.; Behrens J.; Weidner K.M.; Huelsken J.; Birchmeier C.
Epithelial differentiation and the control of metastasis in carcinomas
Current Topics in Microbiology and Immunology : 117-135 (1996-01-01)



Brand-Saberi B.; Mueller T.S.; Wilting J.; Christ B.; Birchmeier C.
Scatter factor hepatocyte growth factor (sf/hgf) induces emigration of myogenic cells at interlimb level in vivo
Developmental Biology 179: 303-308 (1996-01-01)



Sonnenberg-Riethmacher E.; Walter B.; Riethmacher D.; Goedecke S.; Birchmeier C.
The c-ros tyrosine kinase receptor controls regionalization and differentiation of epithelial cells in the epididymis
Genes & Development 10 (10): 1184-1193 (1996-01-01)



1995

Meyer D.; Birchmeier C.
Multiple essential functions of neuregulin in development
Nature 378 (6555): 386-390 (1995-11-23)



Yang Y.; Spitzer E.; Meyer D.; Sachs M.; Niemann C.; Hartmann G.; Weidner K.M.; Birchmeier C.; Birchmeier W.
Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland
Journal of Cell Biology 131 (1): 215-226 (1995-10)



Bladt F.; Riethmacher D.; Isenmann S.; Aguzzi A.; Birchmeier C.
Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud
Nature 376 (6543): 768-771 (1995-08-31)



Schmidt C.; Bladt F.; Goedecke S.; Brinkmann V.; Zschiesche W.; Sharpe M.; Gherardi E.; Birchmeier C.
Scatter factor/hepatocyte growth factor is essential for liver development
Nature 373 (6515): 699-702 (1995-02-23)



Riethmacher D.; Brinkmann V.; Birchmeier C.
A targeted mutation in the mouse E-cadherin gene results in defective preimplantation development
Proceedings of the National Academy of Sciences of the United States of America 92 (3): 855-859 (1995-01-31)



Birchmeier C.; Meyer D.; Riethmacher D.
Factors controlling growth, motility, and morphogenesis of normal and malignant epithelial cells
International Review of Cytology 160: 221-266 (1995-01-01)



Birchmeier W.; Birchmeier C.
Epithelial-mesenchymal transitions in development and tumor progression
Epithelial-Mesenchymal Interactions in Cancer : 1-15 (1995-01-01)



1994

Riethmacher D.; Langholz O.; Goedecke S.; Sachs M.; Birchmeier C.
Biochemical and functional characterization of the murine ros protooncogene
Oncogene 9 (12): 3617-3626 (1994-12)



Birchmeier W.; Birchmeier C.
Mesenchymal-epithelial transitions
BioEssays 16: 305-307 (1994-01-01)



Meyer D.; Birchmeier C.
Distinct isoforms of neuregulin are expressed in mesenchymal and neuronal cells during mouse development
Proceedings of the National Academy of Sciences of the United States of America 91: 1064-1068 (1994-01-01)



1993

Durbeej M.; Soederstroem S.; Ebendal T.; Birchmeier C.; Ekblom P.
Differential expression of neurotrophin receptors during renal development
Development 119 (4): 977-989 (1993-12)



Sonnenberg E.; Meyer D.; Weidner K.M.; Birchmeier C.
Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development
Journal of Cell Biology 123 (1): 223-235 (1993-10-01)



Sonnenberg E.; Weidner K.M.; Birchmeier C.
Expression of the met-receptor and its ligand, HGF-SF during mouse embryogenesis
Hepatocyte Growth Factor-Scatter Factor (HGF-SF) and the C-Met-Receptor : 381-394 (1993-01-01)



Birchmeier C.; Birchmeier W.
Molecular aspects of mesenchymal-epithelial interactions
Annual Review of Cell Biology 9: 511-540 (1993)



Birchmeier C.; Sonnenberg E.; Weidner K.M.; Walter B.
Tyrosine kinase receptors in the control of epithelial growth and morphogenesis during development
BioEssays 15: 185-190 (1993-01-01)



Bladt F.; Birchmeier C.
Characterization and expression analysis of the murine rck gene - a protein-kinase with a potential function in sensory cells
Differentiation 53: 115-122 (1993-01-01)