Publications



2017

Lorenz C.; Lesimple P.; Bukowiecki R.; Zink A.; Inak G.; Mlody B.; Singh M.; Semtner M.; Mah N.; Aure K.; Leong M.; Zabiegalov O.; Lyras E.M.; Pfiffer V.; Fauler B.; Eichhorst J.; Wiesner B.; Huebner N.; Priller J.; Mielke T.; Meierhofer D.; Izsvak Z.; Meier J.C.; Bouillaud F.; Adjaye J.; Schuelke M.; Wanker E.E.; Lombes A.; Prigione A.
Human iPSC-derived neural progenitors are an effective drug discovery model for neurological mtDNA disorders
Cell Stem Cell : (2017-01-26)



2016

Caliskan G.; Mueller I.; Semtner M.; Winkelmann A.; Raza A.S.; Hollnagel J.O.; Roesler A.; Heinemann U.; Stork O.; Meier J.C.
Identification of parvalbumin interneurons as cellular substrate of fear memory persistence
Cerebral Cortex 26 (5): 2325-2340 (2016-05)



2015

Fossati G.; Morini R.; Corradini I.; Antonucci F.; Trepte P.; Edry E.; Sharma V.; Papale A.; Pozzi D.; Defilippi P.; Meier J.C.; Brambilla R.; Turco E.; Rosenblum K.; Wanker E.E.; Ziv N.E.; Menna E.; Matteoli M.
Reduced SNAP-25 increases PSD-95 mobility and impairs spine morphogenesis
Cell Death and Differentiation 22 (9): 1425-1436 (2015-09)



Winkelmann A.; Semtner M.; Meier J.C.
Chloride transporter KCC2-dependent neuroprotection depends on the N-terminal protein domain
Cell Death & Disease 6: e1776 (2015-06-04)



Reinthaler E.M.; Dejanovic B.; Lal D.; Semtner M.; Merkler Y.; Reinhold A.; Pittrich D.A.; Hotzy C.; Feucht M.; Steinboeck H.; Gruber-Sedlmayr U.; Ronen G.; Neophytou B.; Geldner J.; Haberlandt E.; Muhle H.; Ikram M.A.; van Duijn CM.; Uitterlinden A.G.; Hofman A.; Altmueller J.; Kawalia A.; Toliat M.R.; Nuernberg P.; Lerche H.; Nothnagel M.; Thiele H.; Sander T.; Meier J.C.; Schwarz G.; Neubauer B.A.; Zimprich F.
Rare variants in GABA(A) receptor genes in Rolandic epilepsy and related syndromes
Annals of Neurology 77 (6): 972-986 (2015-06)



Winkelmann A.; You X.; Gruenewald N.; Haeussler U.; Krestel H.; Haas C.A.; Schwarz G.; Chen W.; Meier J.C.
Identification of a new genomic hot spot of evolutionary diversification of protein function
PLoS ONE 10 (5): e0125413 (2015-05-08)



Staudacher J.J.; Naarmann-de Vries I.S.; Ujvari S.J.; Klinger B.; Kasim M.; Benko E.; Ostareck-Lederer A.; Ostareck D.H.; Bondke Persson A.; Lorenzen S.; Meier J.C.; Bluethgen N.; Persson P.B.; Henrion-Caude A.; Mrowka R.; Faehling M.
Hypoxia-induced gene expression results from selective mRNA partitioning to the endoplasmic reticulum
Nucleic Acids Research 43 (6): 3219-3236 (2015-03-31)



2014

Kasim M.; Benko E.; Winkelmann A.; Mrowka R.; Staudacher J.J.; Persson P.B.; Scholz H.; Meier J.C.; Fahling M.
Shutdown of achaete-scute homolog-1 expression by heterogeneous nuclear ribonucleoprotein (hnRNP)-A2/B1 in hypoxia
Journal of Biological Chemistry 289 (39): 26973-26988 (2014-09-26)



Foerstera B.; a Dzaye O.D.; Winkelmann A.; Semtner M.; Benedetti B.; Markovic D.S.; Synowitz M.; Wend P.; Faehling M.; Junier M.P.; Glass R.; Kettenmann H.; Meier J.C.
Intracellular glycine receptor function facilitates glioma formation in vivo
Journal of Cell Science 127 (Pt 17): 3687-3698 (2014-09-01)



Dejanovic B.; Semtner M.; Ebert S.; Lamkemeyer T.; Neuser F.; Luescher B.; Meier J.C.; Schwarz G.
Palmitoylation of gephyrin controls receptor clustering and plasticity of GABAergic synapses
PLoS Biology 12 (7): e1001908 (2014-07-15)



Notelaers K.; Rocha S.; Paesen R.; Swinnen N.; Vangindertael J.; Meier J.C.; Rigo J.M.; Ameloot M.; Hofkens J.
Membrane distribution of the glycine receptor {alpha}3 studied by optical super-resolution microscopy
Histochemistry and Cell Biology 142 (1): 79-90 (2014-07)



Meier J.C.; Semtner M.; Winkelmann A.; Wolfart J.
Presynaptic mechanisms of neuronal plasticity and their role in epilepsy
Frontiers in Cellular Neuroscience 8: 164 (2014-06-17)



Notelaers K.; Rocha S.; Paesen R.; Smisdom N.; De Clercq B.; Meier J.C.; Rigo J.M.; Hofkens J.; Ameloot M.
Analysis of {alpha}3 GlyR single particle tracking in the cell membrane
Biochimica et Biophysica Acta - Molecular Cell Research 1843 (3): 544-553 (2014-03)



Winkelmann A.; Maggio N.; Eller J.; Caliskan G.; Semtner M.; Haeussler U.; Juettner R.; Dugladze T.; Smolinsky B.; Kowalczyk S.; Chronowska E.; Schwarz G.; Rathjen F.G.; Rechavi G.; Haas C.A.; Kulik A.; Gloveli T.; Heinemann U.; Meier J.C.
Changes in neural network homeostasis trigger neuropsychiatric symptoms
Journal of Clinical Investigation 124 (2): 696-711 (2014-02-03)



2013

Dugladze T.; Maziashvili N.; Boergers C.; Gurgenidze S.; Haeussler U.; Winkelmann A.; Haas C.A.; Meier J.C.; Vida I.; Kopell N.J.; Gloveli T.
GABA(B) autoreceptor-mediated cell type-specific reduction of inhibition in epileptic mice
Proceedings of the National Academy of Sciences of the United States of America 110 (37): 15073-15078 (2013-09-10)



Kletke O.; Sergeeva O.A.; Lorenz P.; Oberland S.; Meier J.C.; Hatt H.; Gisselmann G.
New insights in endogenous modulation of ligand-gated ion channels: histamine is an inverse agonist at strychnine sensitive glycine receptors
European Journal of Pharmacology 710 (1-3): 59-66 (2013-06-15)



Kowalczyk S.; Winkelmann A.; Smolinsky B.; Foerstera B.; Neundorf I.; Schwarz G.; Meier J.C.
Direct binding of GABA(A) receptor {beta}2 and {beta}3 subunits to gephyrin
European Journal of Neuroscience 37 (4): 544-554 (2013-02)



2012

Notelaers K.; Smisdom N.; Rocha S.; Janssen D.; Meier J.C.; Rigo J.M.; Hofkens J.; Ameloot M.
Ensemble and single particle fluorimetric techniques in concerted action to study the diffusion and aggregation of the glycine receptor {alpha}3 isoforms in the cell plasma membrane
Biochimica et Biophysica Acta - Biomembranes 1818 (12): 3131-3140 (2012-12)



2011

Meier J.C.; Harvey R.J.; Seeburg P.
Frontiers in molecular neuroscience - resume and perspective
Frontiers in Molecular Neuroscience 4: 58 (2011-12)



Grantyn R.; Henneberger C.; Juettner R.; Meier J.C.; Kirischuk S.
Functional hallmarks of GABAergic synapse maturation and the diverse roles of neurotrophins
Frontiers in Cellular Neuroscience 5: 13 (2011-07-04)



Benko E.; Winkelmann A.; Meier J.C.; Persson P.B.; Scholz H.; Faehling M.
Phorbol-ester mediated suppression of hASH1 synthesis: multiple ways to keep the level down
Frontiers in Molecular Neuroscience 4: 1 (2011)



2010

Foerstera B.; Belaidi A.A.; Juettner R.; Bernert C.; Tsokos M.; Lehmann T.N.; Horn P.; Dehnicke C.; Schwarz G.; Meier J.C.
Irregular RNA splicing curtails postsynaptic gephyrin in the cornu ammonis of patients with epilepsy
Brain 133 (Pt12): 3778-3794 (2010-12)



Wisden W.; Meier J.C.
Genetic techniques and circuit analysis
Frontiers in Molecular Neuroscience 3 (3): 4 (2010-03-03)



2009

Legendre P.; Foerstera B.; Juettner R.; Meier J.C.
Glycine receptors caught between genome and proteome – Functional implications of RNA editing and splicing
Frontiers in Molecular Neuroscience 2: 23 (2009-11-09)



Eichler S.A.; Foerstera B.; Smolinsky B.; Juettner R.; Lehmann T.N.; Faehling M.; Schwarz G.; Legendre P.; Meier J.C.
Splice-specific roles of glycine receptor alpha3 in the hippocampus
European Journal of Neuroscience 30 (6): 1077-1091 (2009-09)



Faehling M.; Mrowka R.; Steege A.; Kirschner K.M.; Benko E.; Foerstera B.; Persson P.B.; Thiele B.J.; Meier J.C.; Scholz H.
Translational regulation of the human achaete-scute homologue-1 (hASH1) by fragile x-mental retardation protein (FMRP)
Journal of Biological Chemistry 284 (7): 4255-4266 (2009-02-13)



Chirasani S.R.; Markovic D.S.; Synowitz M.; Eichler S.A.; Wisniewski P.; Kaminska B.; Otto A.; Wanker E.; Schaefer M.; Chiarugi P.; Meier J.C.; Kettenmann H.; Glass R.
Transferrin-receptor-mediated iron accumulation controls proliferation and glutamate release in glioma cells
Journal of Molecular Medicine 87 (2): 153-167 (2009-02)



2008

Eichler S.A.; Kirischuk S.; Juettner R.; Schaefermeier P.K.; Legendre P.; Lehmann T.N.; Gloveli T.; Grantyn R.; Meier J.C.
Glycinergic tonic inhibition of hippocampal neurons with depolarizing GABAergic transmission elicits histopathological signs of temporal lobe epilepsy
Journal of Cellular and Molecular Medicine 12 (6b): 2848-2866 (2008-12)



Smolinsky B.; Eichler S.A.; Burchmeier S.; Meier J.C.; Schwarz G.
Splice-specific functions of gephyrin in molybdenum cofactor biosynthesis
Journal of Biological Chemistry 283 (25): 17370-17379 (2008-06-20)



Eichler S.A.; Meier J.C.
E-I balance and human diseases - from molecules to networking
Frontiers in Molecular Neuroscience 1 (2): (2008-03-28)



2007

Lardi-Studler B.; Smolinsky B.; Petitjean C.M.; Koenig F.; Sidler C.; Meier J.C.; Fritschy J.M.; Schwarz G.
Vertebrate-specific sequences in the gephyrin E-domain regulate cytosolic aggregation and postsynaptic clustering
Journal of Cell Science 120 (Pt 8): 1371-1382 (2007-04-15)



2006

Singh B.; Henneberger C.; Betances D.; Arevalo M.A.; Rodriguez-Tebar A.; Meier J.C.; Grantyn R.
Altered balance of glutamatergic/GABAergic synaptic input and associated changes in dendrite morphology after BDNF expression in BDNF-deficient hippocampal neurons
Journal of Neuroscience 26 (27): 7189-7200 (2006-07-05)



Meier J.C.
Protein kinases and synaptogenesis
Molecular Mechanisms of Synaptogenesis 4: 311-332 (2006)



2005

Meier J.C.; Henneberger C.; Melnick I.; Racca C.; Harvey R.J.; Heinemann U.; Schmieden V.; Grantyn R.
RNA editing produces glycine receptor alpha3(P185L), resulting in high agonist potency
Nature Neuroscience 8 (6): 736-744 (2005-06)



Juettner R.; More M.I.; Das D.; Babich A.; Meier J.; Henning M.; Erdmann B.; Mueller E.C.; Otto A.; Grantyn R.; Rathjen F.G.
Impaired synapse function during postnatal development in the absence of CALEB, an EGF-like protein processed by neuronal activity
Neuron 46 (2): 233-245 (2005-05-21)



Salama-Cohen P.; Arevalo M.A.; Meier J.; Grantyn R.; Rodríguez-Tebar A.
NGF controls dendrite development in hippocampal neurons by binding to p75NTR and modulating the cellular targets of Notch
Molecular Biology of the Cell 16 (1): 339-347 (2005-01)



Henneberger C.; Juettner R.; Schmidt S.A.; Walter J.; Meier J.C.; Rothe T.; Grantyn R.
GluR- and TrkB-mediated maturation of GABA receptor function during the period of eye opening
European Journal of Neuroscience 21 (2): 431-440 (2005-01)



2004

Meier J.; Grantyn R.
A gephyrin-related mechanism restraining glycine receptor anchoring at GABAergic synapses
Journal of Neuroscience 24 (6): 1398-1405 (2004-02-11)



Meier J.; Grantyn R.
Preferential accumulation of GABAA receptor gamma 2L, not gamma 2S, cytoplasmic loops at rat spinal cord inhibitory synapses
Journal of Physiology 559 (Pt 2): 355-365 (2004)



Grantyn R.; Juettner R.; Meier J.
From synapses to maps: Development and use-dependent modification of synaptic connections in the visual layers of the rodent superior colliculus
Methods and New Frontiers in Neuroscience: The superior colliculus : 173-210 (2004)



2003

Meier J.; Schmieden V.
Inhibition of alpha-subunit glycine receptors by quinoxalines
NeuroReport 14 (11): 1507-1510 (2003-08-06)



Meier J.; Akyeli J.; Kirischuk S.; Grantyn R.
GABA(A) receptor activity and PKC control inhibitory synaptogenesis in CNS tissue slices
Molecular and Cellular Neuroscience 23 (4): 600-613 (2003-08)



Meier J.
The enigma of transmitter-selective receptor accumulation at developing inhibitory synapses
Cell and Tissue Research 311 (3): 271-276 (2003-03)



2002

Legendre P.; Muller E.; Badiu C.I.; Meier J.; Vannier C.; Triller A.
Desensitization of homomeric alpha1 glycine receptor increases with receptor density
Molecular Pharmacology 62 (4): 817-827 (2002-10)



Meier J.; Juettner R.; Kirischuk S.; Grantyn R.
Synaptic anchoring of glycine receptors in developing collicular neurons under control of metabotropic glutamate receptor activity
Molecular and Cellular Neuroscience 21 (2): 324-340 (2002-10)



2001

Rosenberg M.; Meier J.; Triller A.; Vannier C.
Dynamics of glycine receptor insertion in the neuronal plasma membrane
Journal of Neuroscience 21 (14): 5036-5044 (2001-07-15)



Juettner R.; Meier J.; Grantyn R.
Slow IPSC kinetics, low levels of alpha1 subunit expression and paired-pulse depression are distinct properties of neonatal inhibitory GABAergic synaptic connections in the mouse superior colliculus
European Journal of Neuroscience 13 (11): 2088-2098 (2001-06)



Meier J.; Vannier C.; Serge A.; Triller A.; Choquet D.
Fast and reversible trapping of surface glycine receptors by gephyrin
Nature Neuroscience 4 (3): 253-260 (2001-03)



2000

Meier J.; De Chaldee M.; Triller A.; Vannier C.
Functional heterogeneity of gephyrins
Molecular and Cellular Neuroscience 16 (5): 566-577 (2000-11)



Meier J.; Meunier-Durmort C.; Forest C.; Triller A.; Vannier C.
Formation of glycine receptor clusters and their accumulation at synapses
Journal of Cell Science 113 (Pt 15): 2783-2795 (2000-08)