Publications



2017

Cerda-Esteban N.; Naumann H.; Ruzittu S.; Mah N.; Pongrac I.M.; Cozzitorto C.; Hommel A.; Andrade-Navarro M.A.; Bonifacio E.; Spagnoli F.M.
Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2
Nature Communications 8: 14127 (2017-02-13)



2016

Kofent J.; Zhang J.; Spagnoli F.M.
The histone methyltransferase Setd7 promotes pancreatic progenitor identity
Development 143 (19): 3573-3581 (2016-10-01)



Kofent J.; Spagnoli F.M.
Xenopus as a model system for studying pancreatic development and diabetes
Seminars in Cell & Developmental Biology 51: 106-116 (2016-03)



2015

Spagnoli F.M.
Simply the right time to turn on insulin
EMBO Journal 34 (13): 1740-1742 (2015-07-02)



Heinrichs C.; Spagnoli F.M.; Berninger B.
In vivo reprogramming for tissue repair
Nature Cell Biology 17 (3): 204-211 (2015-02-27)



2014

Simaite D.; Kofent J.; Gong M.; Rueschendorf F.; Jia S.; Arn P.; Bentler K.; Ellaway C.; Kuehnen P.; Hoffmann G.F.; Blau N.; Spagnoli F.M.; Huebner N.; Raile K.
Recessive mutations in PCBD1 cause a new type of early-onset diabetes
Diabetes 63 (10): 3557-3564 (2014-10)



Cerda-Esteban N.; Spagnoli F.M.
Glimpse into Hox and tale regulation of cell differentiation and reprogramming
Developmental Dynamics 243 (1): 76-87 (2014-01)



2013

Rodriguez-Seguel E.; Mah N.; Naumann H.; Pongrac I.M.; Cerda-Esteban N.; Fontaine J.F.; Wang Y.; Chen W.; Andrade-Navarro M.A.; Spagnoli F.M.
Mutually exclusive signaling signatures define the hepatic and pancreatic progenitor cell lineage divergence
Genes & Development 27 (17): 1932-1946 (2013-09-01)



Gong M.; Simaite D.; Kuehnen P.; Heldmann M.; Spagnoli F.; Blankenstein O.; Huebner N.; Hussain K.; Raile K.
Two novel GATA6 mutations cause childhood-onset diabetes mellitus, pancreas malformation and congenital heart disease
Hormone Research in Paediatrics 79 (4): 250-256 (2013-05)



Zygmunt T.; Spagnoli F.M.
RhoGAP control of pancreas development: putting cells in the right place at the right time
Small GTPases 4 (2): 127-131 (2013-04)



Petzold K.M.; Naumann H.; Spagnoli F.M.
Rho signalling restriction by the RhoGAP Stard13 integrates growth and morphogenesis in the pancreas
Development 140 (1): 126-135 (2013-01-01)



2012

Petzold K.M.; Spagnoli F.M.
A system for ex vivo culturing of embryonic pancreas
Journal of Visualized Experiments (66): e3979 (2012-08-27)



Spagnoli F.M.; Besser D.; Benitah S.A.
Where do you come from; where do you go? Pluripotency, differentiation and malfunction of stem cells
EMBO Reports 13 (1): 9-11 (2012-01)



2009

Rosa A.; Spagnoli F.M.; Brivanlou A.H.
The miR-430/427/302 family controls mesendodermal fate specification via species-specific target selection
Developmental Cell 16 (4): 517-527 (2009-04-21)



2008

Spagnoli F.M.; Brivanlou A.H.
The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm
Development 135 (3): 451-461 (2008-02)



2007

Spagnoli F.M.
From endoderm to pancreas: a multistep journey
Cellular and Molecular Life Sciences 64 (18): 2378-2390 (2007-09)



Sapkota G.; Alarcon C.; Spagnoli F.M.; Brivanlou A.H.; Massague J.
Balancing BMP signaling through integrated inputs into the Smad1 linker
Molecular Cell 25 (3): 441-454 (2007-02-09)



2006

Cicchini C.; Filippini D.; Coen S.; Marchetti A.; Cavallari C.; Laudadio I.; Spagnoli F.M.; Alonzi T.; Tripodi M.
Snail controls differentiation of hepatocytes by repressing HNF4alpha expression
Journal of Cellular Physiology 209 (1): 230-238 (2006-10)



Spagnoli F.M.; Hemmati-Brivanlou A.
Guiding embryonic stem cells towards differentiation: lessons from molecular embryology
Current Opinion in Genetics & Development 16 (5): 469-475 (2006-10)



Spagnoli F.M.; Brivanlou A.H.
The RNA-binding protein, Vg1RBP, is required for pancreatic fate specification
Developmental Biology 292 (2): 442-456 (2006-04-15)



2005

Spagnoli F.M.; Brivanlou A.H.
A full menu for stem-cell research
Genome Biology 6 (3): 311 (2005)



2000

Spagnoli F.M.; Cicchini C.; Tripodi M.; Weiss M.C.
Inhibition of MMH (Met murine hepatocyte) cell differentiation by TGF(beta) is abrogated by pre-treatment with the heritable differentiation effector FGF1
Journal of Cell Science 113 (Pt 20): 3639-3647 (2000-10)



1998

Spagnoli F.M.; Amicone L.; Tripodi M.; Weiss M.C.
Identification of a bipotential precursor cell in hepatic cell lines derived from transgenic mice expressing cyto-Met in the liver
Journal of Cell Biology 143 (4): 1101-1112 (1998-11-16)



1997

Amicone L.; Spagnoli F.M.; Spaeth G.; Giordano S.; Tommasini C.; Bernardini S.; De Luca V.; Della Rocca C.; Weiss M.C.; Comoglio P.M.; Tripodi M.
Transgenic expression in the liver of truncated Met blocks apoptosis and permits immortalization of hepatocytes
EMBO Journal 16 (3): 495-503 (1997-02-03)



1995

Amicone L.; Galimi M.A.; Spagnoli F.M.; Tommasini C.; De Luca V.; Tripodi M.
Temporal and tissue-specific expression of the MET ORF driven by the complete transcriptional unit of human A1AT gene in transgenic mice
Gene 162 (2): 323-328 (1995-09-11)