Publications



2017

Raifman T.K.; Kumar P.; Haase H.; Klussmann E.; Dascal N.; Weiss S.
Protein kinase C enhances plasma membrane expression of cardiac L-type calcium channel, CaV1.2
Channels : (2017-09-13)



Oz S.; Pankonien I.; Belkacemi A.; Flockerzi V.; Klussmann E.; Haase H.; Dascal N.
Protein kinase A regulates C-terminally truncated CaV 1.2 in Xenopus oocytes: roles of N- and C-termini of the {alpha}1C subunit
Journal of Physiology 595 (10): 3181-3202 (2017-05-15)



2016

Eccles R.L.; Czajkowski M.T.; Barth C.; Mueller P.M.; McShane E.; Grunwald S.; Beaudette P.; Mecklenburg N.; Volkmer R.; Zuehlke K.; Dittmar G.; Selbach M.; Hammes A.; Daumke O.; Klussmann E.; Urbe S.; Rocks O.
Bimodal antagonism of PKA signalling by ARHGAP36
Nature Communications 7: 12963 (2016-10-07)



van den Born B.J.H.; Oskam L.C.; Zidane M.; Schaechterle C.; Klussmann E.; Baehring S.; Luft F.C.
The Case : a handful of hypertension
Kidney International 90 (4): 911-913 (2016-10)



Dema A.; Schroeter M.F.; Perets E.; Skroblin P.; Moutty M.C.; Deak V.A.; Birchmeier W.; Klussmann E.
The A-kinase anchoring protein (AKAP) glycogen synthase kinase 3{beta} interaction protein (GSKIP) regulates {beta}-catenin through its interactions with both protein kinase A (PKA) and GSK3{beta}
Journal of Biological Chemistry 291 (37): 19618-19630 (2016-09-09)



Deak V.A.; Klussmann E.
Pharmacological interference with protein-protein interactions of A-kinase anchoring proteins as a strategy for the treatment of disease
Current Drug Targets 17 (10): 1147-1171 (2016-08-01)



Klussmann E.
Protein-protein interactions of PDE4 family members - Functions, interactions and therapeutic value
Cellular Signalling 28 (7): 713-718 (2016-07)



Goetz F.; Roske Y.; Schulz M.S.; Autenrieth K.; Bertinetti D.; Faelber K.; Zuehlke K.; Kreuchwig A.; Kennedy E.; Krause G.; Daumke O.; Herberg F.W.; Heinemann U.; Klussmann E.
AKAP18:PKA-RII{alpha} structure reveals crucial anchor points for recognition of regulatory subunits of PKA
Biochemical Journal 473 (13): 1881-1894 (2016-06-28)



Vukicevic T.; Schulz M.; Faust D.; Klussmann E.
The trafficking of the water channel aquaporin-2 in renal principal cells-a potential target for pharmacological intervention in cardiovascular diseases
Frontiers in Pharmacology 7: 23 (2016-02-11)



Deak V.A.; Skroblin P.; Dittmayer C.; Knobeloch K.P.; Bachmann S.; Klussmann E.
The A-kinase anchoring protein GSKIP regulates GSK3{beta} activity and controls palatal shelf fusion in mice
Journal of Biological Chemistry 291 (2): 681-690 (2016-01-08)



2015

Dema A.; Perets E.; Schulz M.S.; Deak V.A.; Klussmann E.
Pharmacological targeting of AKAP-directed compartmentalized cAMP signalling
Cellular Signalling 27 (12): 2474-2487 (2015-12)



Toka O.; Tank J.; Schaechterle C.; Aydin A.; Maass P.G.; Elitok S.; Bartels-Klein E.; Hollfinger I.; Lindschau C.; Mai K.; Boschmann M.; Rahn G.; Movsesian M.A.; Mueller T.; Doescher A.; Gnoth S.; Muehl A.; Toka H.R.; Wefeld-Neuenfeld Y.; Utz W.; Toepper A.; Jordan J.; Schulz-Menger J.; Klussmann E.; Baehring S.; Luft F.C.
Clinical effects of phosphodiesterase 3A mutations in inherited hypertension with brachydactyly
Hypertension 66 (4): 800-808 (2015-10)



Hermann J.S.; Skroblin P.; Bertinetti D.; Hanold L.E.; von der Heide E.K.; Wagener E.M.; Zenn H.M.; Klussmann E.; Kennedy E.J.; Herberg F.W.
Neurochondrin is an atypical RII{alpha}-specific A-kinase anchoring protein
Biochimica et Biophysica Acta - Proteins and Proteomics 1854 (10 Pt B): 1667-1675 (2015-10)



Maass P.G.; Aydin A.; Luft F.C.; Schaechterle C.; Weise A.; Stricker S.; Lindschau C.; Vaegler M.; Qadri F.; Toka H.R.; Schulz H.; Krawitz P.M.; Parkhomchuk D.; Hecht J.; Hollfinger I.; Wefeld-Neuenfeld Y.; Bartels-Klein E.; Muehl A.; Kann M.; Schuster H.; Chitayat D.; Bialer M.G.; Wienker T.F.; Ott J.; Rittscher K.; Liehr T.; Jordan J.; Plessis G.; Tank J.; Mai K.; Naraghi R.; Hodge R.; Hopp M.; Hattenbach L.O.; Busjahn A.; Rauch A.; Vandeput F.; Gong M.; Rueschendorf F.; Huebner N.; Haller H.; Mundlos S.; Bilginturan N.; Movsesian M.A.; Klussmann E.; Toka O.; Baehring S.
PDE3A mutations cause autosomal dominant hypertension with brachydactyly
Nature Genetics 47 (6): 647-653 (2015-06)



Poppinga W.J.; Heijink I.H.; Holtzer L.J.; Skroblin P.; Klussmann E.; Halayko A.J.; Timens W.; Maarsingh H.; Schmidt M.
A-kinase anchoring proteins coordinate inflammatory responses to cigarette smoke in airway smooth muscle
American Journal of Physiology Lung Cellular and Molecular Physiology 308 (8): L766-L775 (2015-04-15)



Bolger G.B.; Dunlop A.J.; Meng D.; Day J.P.; Klussmann E.; Baillie G.S.; Adams D.R.; Houslay M.D.
Dimerization of cAMP phosphodiesterase-4 (PDE4) in living cells requires interfaces located in both the UCR1 and catalytic unit domains
Cellular Signalling 27 (4): 756-769 (2015-04)



Ahmad F.; Shen W.; Vandeput F.; Szabo-Fresnais N.; Krall J.; Degerman E.; Goetz F.; Klussmann E.; Movsesian M.; Manganiello V.
Regulation of sarcoplasmic reticulum Ca2+ ATPase 2 (SERCA2) activity by phosphodiesterase 3A (PDE3A) in human myocardium: phosphorylation-dependent interaction of PDE3A1 with SERCA2
Journal of Biological Chemistry 290 (11): 6763-6776 (2015-03-13)



Schaechterle C.; Christian F.; Fernandes J.M.P.; Klussmann E.
Screening for small molecule disruptors of AKAP-PKA interactions
Methods in Molecular Biology 1294: 151-166 (2015-03-02)



Laster B.H.; Isaacson C.; Perets E.; Msamra M.; Priel E.; Kalef-Ezra J.; Kost J.
Keeping those telomeres short! an innovative intratumoral long-term drug delivery system
Journal of Cancer Research and Clinical Oncology 141 (1): 23-34 (2015-01)



2014

Abdul Azeez K.R.; Knapp S.; Fernandes J.M.P.; Klussmann E.; Elkins J.M.
The crystal structure of the RhoA-AKAP-Lbc DH-PH domain complex
Biochemical Journal 464 (2): 231-239 (2014-12-01)



El-Dahshan A.; Al-Gharabli S.I.; Radetzki S.; Al-Tel T.H.; Kumar P.; Rademann J.
Flexible, polymer-supported synthesis of sphingosine derivatives provides ceramides with enhanced biological activity
Bioorganic and Medicinal Chemistry 22 (19): 5506-5512 (2014-10-01)



Yu X.; Li F.; Klussmann E.; Stallone J.N.; Han G.
G protein-coupled estrogen receptor 1 (GPER) mediates relaxation of coronary arteries via cAMP/PKA-dependent activation of MLCP
American Journal of Physiology Endocrinology and Metabolism 307 (4): E398-E407 (2014-08-15)



2013

Schaefer G.; Milic J; Eldahshan A; Goetz F.; Zuehlke K.; Schillinger C.; Kreuchwig A.; Elkins J.M.; Abdul Azeez K.R.A.; Oder A.; Moutty M.C.; Masada N.; Beerbaum M.; Schlegel B.; Niquet S.; Schmieder P.; Krause G.; von Kries J.P.; Cooper D.M.F.; Knapp S.; Rademann J.; Rosenthal W.; Klussmann E.
Highly functionalized terpyridines as competitive inhibitors of AKAP-PKA interactions
Angewandte Chemie International Edition 52 (46): 12187-12191 (2013-11-11)



Scheunemann L.; Skroblin P.; Hundsrucker C.; Klussmann E.; Efetova M.; Schwaerzel M.
AKAPS act in a two-step mechanism of memory acquisition
Journal of Neuroscience 33 (44): 17422-17428 (2013-10-30)



Faust D.; Geelhaar A.; Eisermann B.; Eichhorst J.; Wiesner B.; Rosenthal W.; Klussmann E.
Culturing primary rat inner medullary collecting duct cells
Journal of Visualized Experiments (76): e50366 (2013-06-21)



Bogum J.; Faust D.; Zuehlke K.; Eichhorst J.; Moutty M.C.; Furkert J.; Eldahshan A.; Neuenschwander M.; von Kries J.P.; Wiesner B.; Trimpert C.; Deen P.M.; Valenti G.; Rosenthal W.; Klussmann E.
Small-molecule screening identifies modulators of aquaporin-2 trafficking
Journal of the American Society of Nephrology 24 (5): 744-758 (2013-04)



2012

Horner A.; Goetz F.; Tampe R.; Klussmann E.; Pohl P.
Mechanism for targeting the A-kinase anchoring protein AKAP18{delta} to the membrane
Journal of Biological Chemistry 287 (51): 42495-42501 (2012-12-14)



Trimpert C.; van den Berg D.T.M.; Fenton R.A.; Klussmann E.; Deen P.M.T.
Vasopressin increases S261 phosphorylation in AQP2-P262L, a mutant in recessive nephrogenic diabetes insipidus
Nephrology Dialysis Transplantation 27 (12): 4389-4397 (2012-12)



Willoughby D.; Halls M.L.; Everett K.L.; Skroblin P.; Klussmann E.; Cooper D.M.F.
A key phosphorylation site in AC8 mediates regulation of Ca2+-dependent cAMP dynamics by an AC8-AKAP79-PKA signalling complex
Journal of Cell Science 125 (Pt 23): 5850-5859 (2012-12-01)



Troeger J.; Moutty M.C.; Skroblin P.; Klussmann E.
A-kinase anchoring proteins as potential drug targets
British Journal of Pharmacology 166 (2): 420-433 (2012-05)



Willoughby D.; Everett K.L.; Halls M.L.; Pacheco J.; Skroblin P.; Vaca L.; Klussmann E.; Cooper D.M.
Direct binding between Orai1 and AC8 mediates dynamic interplay between Ca2+ and cAMP signaling
Science Signaling 5 (219): ra29 (2012-04-10)



2011

da Costa Goncalves A.C.; Fontes M.A.; Klussmann E.; Qadri F.; Janke J.; Gollasch M.; Schleifenbaum J.; Mueller D.; Jordan J.; Tank J.; Luft F.C.; Gross V.
Spinophilin regulates central angiotensin II-mediated effect on blood pressure
Journal of Molecular Medicine 89 (12): 1219-1229 (2011-12)



Murdoch H.; Vadrevu S.; Prinz A.; Dunlop A.J.; Klussmann E.; Bolger G.B.; Norman J.C.; Houslay M.D.
Interaction between LIS1 and PDE4, and its role in cytoplasmic dynein function
Journal of Cell Science 124 (Pt 13): 2253-2266 (2011-07-01)



Day J.P.; Lindsay B.; Riddell T.; Jiang Z.; Allcock R.W.; Abraham A.; Sookup S.; Christian F.; Bogum J.; Martin E.K.; Rae R.L.; Anthony D.; Rosair G.M.; Houslay D.M.; Huston E.; Baillie G.S.; Klussmann E.; Houslay M.D.; Adams D.R.
Elucidation of a structural basis for the inhibitor-driven, p62 (SQSTM1)-dependent intracellular redistribution of cAMP phosphodiesterase-4A4 (PDE4A4)
Journal of Medicinal Chemistry 54 (9): 3331-3347 (2011-05-12)



Christian F.; Szaszak M.; Friedl S.; Drewianka S.; Lorenz D.; Goncalves A.; Furkert J.; Vargas C.; Schmieder P.; Goetz F.; Zuehlke K.; Moutty M.; Goettert H.; Joshi M.; Reif B.; Haase H.; Morano I.; Grossmann S.; Klukovits A.; Verli J.; Gaspar R.; Noack C.; Bergmann M.; Kass R.; Hampel K.; Kashin D.; Genieser H.G.; Herberg F.W.; Willoughby D.; Cooper D.M.; Baillie G.S.; Houslay M.D.; von Kries J.P.; Zimmermann B.; Rosenthal W.; Klussmann E.
Small molecule AKAP/PKA interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes
Journal of Biological Chemistry 286 (11): 9079-9096 (2011-03-18)



2010

Mollajew R.; Zocher F.; Horner A.; Wiesner B.; Klussmann E.; Pohl P.
Routes of epithelial water flow: aquaporins versus cotransporters
Biophysical Journal 99 (11): 3647-3656 (2010-12-01)



Nedvetsky P.I.; Tabor V.; Tamma G.; Beulshausen S.; Skroblin P.; Kirschner A.; Mutig K.; Boltzen M.; Petrucci O.; Vossenkaemper A.; Wiesner B.; Bachmann S.; Rosenthal W.; Klussmann E.
Reciprocal regulation of aquaporin-2 abundance and degradation by protein kinase A and p38-MAP kinase
Journal of the American Society of Nephrology 21 (10): 1645-1656 (2010-10)



Li X.; Vadrevu S.; Dunlop A.; Day J.; Advant N.; Troeger J.; Klussmann E.; Jaffrey E.; Hay R.T.; Adams D.R.; Houslay M.D.; Baillie G.S.
Selective SUMO modification of cAMP-specific phosphodiesterase-4D5 (PDE4D5) regulates the functional consequences of phosphorylation by PKA and ERK
Biochemical Journal 428 (1): 55-65 (2010-05-15)



Hundsrucker C.; Skroblin P.; Christian F.; Zenn M.; Popara V.; Joshi M.; Eichhorst J.; Wiesner B.; Herberg F.W.; Reif B.; Rosenthal W.; Klussmann E.
Glycogen synthase kinase 3{beta} interaction protein functions as an A-kinase anchoring protein
Journal of Biological Chemistry 285 (8): 5507-5521 (2010-02-19)



Skroblin P.; Grossmann S.; Schaefer G.; Rosenthal W.; Klussmann E.
Mechanisms of protein kinase A anchoring
International Review of Cell and Molecular Biology 283 (C): 235-330 (2010)



2009

Meng D.; Lynch M.J.; Huston E.; Beyermann M.; Eichhorst J.; Adams D.R.; Klussmann E.; Houslay M.D.; Baillie G.S.
MEK1 binds directly to betaarrestin1, influencing both its phosphorylation by ERK and the timing of its isoprenaline-stimulated internalization
Journal of Biological Chemistry 284 (17): 11425-1135 (2009-04-24)



Nedvetsky P.I.; Tamma G.; Beulshausen S.; Valenti G.; Rosenthal W.; Klussmann E.
Regulation of aquaporin-2 trafficking
Handbook of Experimental Pharmacology 190 (II): 133-157 (2009)



2008

Szaszak M.; Christian F.; Rosenthal W.; Klussmann E.
Compartmentalized cAMP signalling in regulated exocytic processes in non-neuronal cells
Cellular Signalling 20 (4): 590-601 (2008-04)



Hundsrucker C.; Klussmann E.
Direct AKAP-mediated protein-protein interactions as potential drug targets
Handbook of Experimental Pharmacology 186: 483-503 (2008)



2007

Smith K.J.; Baillie G.S.; Hyde E.I.; Li X.; Houslay T.M.; McCahill A.; Dunlop A.J.; Bolger G.B.; Klussmann E.; Adams D.R.; Houslay M.D.
1H NMR structural and functional characterisation of a cAMP-specific phosphodiesterase-4D5 (PDE4D5) N-terminal region peptide that disrupts PDE4D5 interaction with the signalling scaffold proteins, beta-arrestin and RACK1
Cellular Signalling 19 (12): 2612-2624 (2007-12)



Lygren B.; Carlson C.R.; Santamaria K.; Lissandron V.; McSorley T.; Litzenberg J.; Lorenz D.; Wiesner B.; Rosenthal W.; Zaccolo M.; Tasken K.; Klussmann E.
AKAP complex regulates Ca2+ re-uptake into heart sarcoplasmic reticulum
EMBO Reports 8 (11): 1061-1067 (2007-11-01)



Vossenkaemper A.; Nedvetsky P.I.; Wiesner B.; Furkert J.; Rosenthal W.; Klussmann E.
Microtubules are needed for the perinuclear positioning of aquaporin-2 after its endocytic retrieval in renal principal cells
American Journal of Physiology Cell Physiology 293 (3): C1129-C1138 (2007-09-11)



Murdoch H.; Mackie S.; Collins D.M.; Hill E.V.; Bolger G.B.; Klussmann E.; Porteous D.J.; Millar J.K.; Houslay M.D.
Isoform-selective susceptibility of DISC1/phosphodiesterase-4 complexes to dissociation by elevated intracellular cAMP levels
Journal of Neuroscience 27 (35): 9513-9524 (2007-08-29)



Sachs B.D.; Baillie G.S.; McCall J.R.; Passino M.A.; Schachtrup C.; Wallace D.A.; Dunlop A.J.; MacKenzie K.F.; Klussmann E.; Lynch M.J.; Sikorski S.L.; Nuriel T.; Tsigelny I.; Zhang J.; Houslay M.D.; Chao M.V.; Akassoglou K.
p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway
Journal of Cell Biology 177 (6): 1119-1132 (2007-06-18)



Baillie G.S.; Adams D.R.; Bhari N.; Houslay T.M.; Vadrevu S.; Meng D.; Li X.; Dunlop A.; Milligan G.; Bolger G.B.; Klussmann E.; Houslay M.D.
Mapping binding sites for the PDE4D5 cAMP-specific phosphodiesterase to the N- and C-domains of beta-arrestin using spot-immobilized peptide arrays
Biochemical Journal 404 (1): 71-80 (2007-05-15)



Nedvetsky P.I.; Stefan E.; Frische S.; Santamaria K.; Wiesner B.; Valenti G.; Hammer J.A.; Nielsen S.; Goldenring J.R.; Rosenthal W.; Klussmann E.
A role of myosin Vb and Rab11-FIP2 in the aquaporin-2 shuttle
Traffic 8 (2): 110-123 (2007-02)



Klussmann E.
Protein-protein interactions as target for new therapeutic molecules
BIOforum Europe 3: 18-19 (2007)



Klussmann E.
Protein-Protein-Interaktionen als Ziel fuer neue Pharmaka : EU-Projekt thera-cAMP
BIOforum 2: 32-34 (2007)



Stefan E.; Wiesner B.; Baillie G.S.; Mollajew R.; Henn V.; Lorenz D.; Furkert J.; Santamaria K.; Nedvetsky P.I.; Hundsrucker C.; Beyermann M.; Krause E.; Pohl P.; Gall I.; MacIntyre A.N.; Bachmann S.; Houslay M.D.; Rosenthal W.; Klussmann E.
Compartmentalization of cAMP-dependent signaling by phosphodiesterase-4D is involved in the regulation of vasopressin-mediated water reabsorption in renal principal cells
Journal of the American Society of Nephrology 18 (1): 199-212 (2007-01)



2006

Bolger G.B.; Baillie G.S.; Li X.; Lynch M.J.; Herzyk P.; Mohamed A.; Mitchell L.H.; McCahill A.; Hundsrucker C.; Klussmann E.; Adams D.R.; Houslay M.D.
Scanning peptide array analyses identify overlapping binding sites for the signalling scaffold proteins, beta-arrestin and RACK1, in cAMP-specific phosphodiesterase PDE4D5
Biochemical Journal 398 (1): 23-36 (2006-08-15)



Hundsrucker C.; Rosenthal W.; Klussmann E.
Peptides for disruption of PKA anchoring
Biochemical Society Transactions 34 (Pt 4): 472-473 (2006-08-01)



Klussmann E.
First international meeting on anchored cAMP signaling pathways, Biomedical Campus, Berlin-Buch, Germany, 15-16 October 2005
European Journal of Cell Biology 85 (7): 581-584 (2006-07-05)



McSorley T.; Stefan E.; Henn V.; Wiesner B.; Baillie G.S.; Houslay M.D.; Rosenthal W.; Klussmann E.
Spatial organisation of AKAP18 and PDE4 isoforms in renal collecting duct principal cells
European Journal of Cell Biology 85 (7): 673-678 (2006-07-05)



Hundsrucker C.; Krause G.; Beyermann M.; Prinz A.; Zimmermann B.; Diekmann O.; Lorenz D.; Stefan E.; Nedvetsky P.; Dathe M.; Christian F.; McSorley T.; Krause E.; McConnachie G.; Herberg F.W.; Scott J.D.; Rosenthal W.; Klussmann E.
High-affinity AKAP7delta-protein kinase A interaction yields novel protein kinase A-anchoring disruptor peptides
Biochemical Journal 396 (2): 297-306 (2006-06-01)



Klussmann E.; Rosenthal W.
AKAP7
UCSD Nature Molecule Pages : (2006-04-04)



2005

Henn V.; Stefan E.; Baillie G.S.; Houslay M.D.; Rosenthal W.; Klussmann E.
Compartmentalized cAMP signalling regulates vasopressin-mediated water reabsorption by controlling aquaporin-2
Biochemical Society Transactions 33 (Pt 6): 1316-1318 (2005-12)



Lynch M.J.; Baillie G.S.; Mohamed A.; Li X.; Maisonneuve C.; Klussmann E.; van Heeke G.; Houslay M.D.
RNA silencing identifies PDE4D5 as the functionally relevant cAMP phosphodiesterase interacting with beta arrestin to control the protein kinase A/AKAP79-mediated switching of the beta2-adrenergic receptor to activation of ERK in HEK293B2 cells
Journal of Biological Chemistry 280 (39): 33178-33189 (2005-09-30)



Tamma G.; Klussmann E.; Oehlke J.; Krause E.; Rosenthal W.; Svelto M.; Valenti G.
Actin remodeling requires ERM function to facilitate AQP2 apical targeting
Journal of Cell Science 118 (Pt 16): 3623-3630 (2005-08-15)



2004

Henn V.; Edemir B.; Stefan E.; Wiesner B.; Lorenz D.; Theilig F.; Schmitt R.; Vossebein L.; Tamma G.; Beyermann M.; Krause E.; Herberg F.W.; Valenti G.; Bachmann S.; Rosenthal W.; Klussmann E.
Identification of a novel A-kinase anchoring protein 18 isoform and evidence for its role in the vasopressin-induced aquaporin-2 shuttle in renal principal cells
Journal of Biological Chemistry 279 (25): 26654-26665 (2004-06-18)



2003

Tamma G.; Wiesner B.; Furkert J.; Hahm D.; Oksche A.; Schaefer M.; Valenti G.; Rosenthal W.; Klussmann E.
The prostaglandin E2 analogue sulprostone antagonizes vasopressin-induced antidiuresis through activation of Rho
Journal of Cell Science 116 (Pt 16): 3285-3294 (2003-08-15)



Schmitt R.; Klussmann E.; Kahl T.; Ellison D.H.; Bachmann S.
Renal expression of sodium transporters and aquaporin-2 in hypothyroid rats
American Journal of Physiology Renal Physiology 284 (5): F1097-F1104 (2003-05)



Tamma G.; Klussmann E.; Procino G.; Svelto M.; Rosenthal W.; Valenti G.
cAMP-induced AQP2 translocation is associated with RhoA inhibition through RhoA phosphorylation and interaction with RhoGDI
Journal of Cell Science 116 (Pt 8): 1519-1525 (2003-04-15)



Storm R.; Klussmann E.; Geelhaar A.; Rosenthal W.; Maric K.
Osmolality and solute composition are strong regulators of AQP2 expression in renal principal cells
American Journal of Physiology Renal Physiology 284 (1): F189-F198 (2003-01)



2001

Tamma G.; Klussmann E.; Maric K.; Aktories K.; Svelto M.; Rosenthal W.; Valenti G.
Rho inhibits cAMP-induced translocation of aquaporin-2 into the apical membrane of renal cells
American Journal of Physiology Renal Physiology 281 (6): F1092-F1101 (2001-12)



Klussmann E.; Edemir B.; Pepperle B.; Tamma G.; Henn V.; Klauschenz E.; Hundsrucker C.; Maric K.; Rosenthal W.
Ht31: the first protein kinase A anchoring protein to integrate protein kinase A and Rho signaling
FEBS Letters 507 (3): 264-268 (2001-11-02)



Klussmann E.; Rosenthal W.
Role and identification of protein kinase A anchoring proteins in vasopressin-mediated aquaporin-2 translocation
Kidney International 60 (2): 446-449 (2001-08)



Klussmann E.; Tamma G.; Lorenz D.; Wiesner B.; Maric K.; Hofmann F.; Aktories K.; Valenti G.; Rosenthal W.
An inhibitory role of Rho in the vasopressin-mediated translocation of aquaporin-2 into cell membranes of renal principal cells
Journal of Biological Chemistry 276 (23): 20451-20457 (2001-06-08)



Maric K.; Wiesner B.; Lorenz D.; Klussmann E.; Betz T.; Rosenthal W.
Cell volume kinetics of adherent epithelial cells measured by laser scanning reflection microscopy: determination of water permeability changes of renal principal cells
Biophysical Journal 80 (4): 1783-1790 (2001-04)



2000

Klussmann E.; Maric K.; Rosenthal W.
The mechanisms of aquaporin control in the renal collecting duct
Reviews of Physiology Biochemistry and Pharmacology 141: 33-95 (2000)



1999

Klussmann E.; Maric K.; Wiesner B.; Beyermann M.; Rosenthal W.
Protein kinase A anchoring proteins are required for vasopressin-mediated translocation of aquaporin-2 into cell membranes of renal principal cells
Journal of Biological Chemistry 274 (8): 4934-4938 (1999-02-19)



1997

Hanski C.; Riede E.; Gratchev A.; Foss H.D.; Boehm C.; Klussmann E.; Hummel M.; Mann B.; Buhr H.J.; Stein H.; Kim Y.S.; Gum J.; Riecken E.O.
MUC2 gene suppression in human colorectal carcinomas and their metastases: in vitro evidence of the modulatory role of DNA methylation
Laboratory Investigation 77 (6): 685-695 (1997-12)



Mann B.; Klussmann E.; Vandamme-Feldhaus V.; Iwersen M.; Hanski M.L.; Riecken E.O.; Buhr H.J.; Schauer R.; Kim Y.S.; Hanski C.
Low O-acetylation of sialyl-Le(x) contributes to its overexpression in colon carcinoma metastases
International Journal of Cancer 72 (2): 258-264 (1997-07-17)



1996

Hanski C.; Klussmann E.; Wang J.; Boehm C.; Ogorek D.; Hanski M.L.; Krueger-Krasagakes S.; Eberle J.; Schmitt-Graeff A.; Riecken E.O.
Fucosyltransferase III and sialyl-Le(x) expression correlate in cultured colon carcinoma cells but not in colon carcinoma tissue
Glycoconjugate Journal 13 (5): 727-733 (1996-10)



1994

Blanke M.; Klussmann E.; Krueger-Krasagakes S.; Schmitt-Graeff A.; Stolte M.; Bornhoeft G.; Stein H.; Xing P.X.; McKenzie I.F.; Verstijnen C.P.; Riecken E.O.; Hanski C.
Expression of MUC2-mucin in colorectal adenomas and carcinomas of different histological types
International Journal of Cancer 59 (3): 301-306 (1994-11-01)



1993

Hanski C.; Drechsler K.; Hanisch F.G.; Sheehan J.; Manske M.; Ogorek D.; Klussmann E.; Hanski M.L.; Blank M.; Xing P.X.; McKenzie I.F.C.; Devine P.L.; Riecken E.O.
Altered glycosylation of the MUC-1 protein core contributes to the colon carcinoma-associated increase of mucin-bound sialyl-Lewis(x) expression
Cancer Research 53 (17): 4082-4088 (1993-09-01)