Novel signals guiding endodermal progenitors toward pancreatic fate

Figure 4

Branching pancreatic epithelium


In another line of research, we are investigating molecular players that act as morphogenetic

factors during early pancreatic development. In the developing pancreas, the branching epithelium

is organized in discrete domains, delineating one specific domain of progenitor cells at the tip of

the branches. Ongoing projects in the lab aim at understanding how morphogenesis controls

progenitor cell proliferation and different cell types specification.