Publications



2017

Paul F.; Zauber H.; von Berg L.; Rocks O.; Daumke O.; Selbach M.
Quantitative GTPase affinity purification identifies Rho family protein interaction partners
Molecular & Cellular Proteomics 16 (1): 73-85 (2017-01-01)



2016

Arumughan A.; Roske Y.; Barth C.; Lleras Forero L.; Bravo-Rodriguez K.; Redel Al.; Kostova S.; McShane E.; Opitz R.; Faelber K.; Rau K.; Mielke T.; Daumke O.; Selbach M.; Sanchez-Garcia E.; Rocks O.; Panakova D.; Heinemann U.; Wanker E.E.
Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers
Nature Communications 7: 13047 (2016-10-20)



Eccles R.L.; Czajkowski M.T.; Barth C.; Mueller P.M.; McShane E.; Grunwald S.; Beaudette P.; Mecklenburg N.; Volkmer R.; Zuehlke K.; Dittmar G.; Selbach M.; Hammes A.; Daumke O.; Klussmann E.; Urbe S.; Rocks O.
Bimodal antagonism of PKA signalling by ARHGAP36
Nature Communications 7: 12963 (2016-10-07)



Becker M.S.; Mueller P.M.; Bajorat J.; Schroeder A.; Giaisi M.; Amin E.; Ahmadian M.R.; Rocks O.; Koehler R.; Krammer P.H.; Li-Weber M.
The anticancer phytochemical rocaglamide inhibits Rho GTPase activity and cancer cell migration
Oncotarget 7 (32): 51908-51921 (2016-08-09)



Casado-Medrano V.; Barrio-Real L.; Garcia-Rostan G.; Baumann M.; Rocks O.; Caloca M.J.
A new role of the Rac-GAP {beta}2-chimaerin in cell adhesion reveals opposite functions in breast cancer initiation and tumor progression
Oncotarget 7 (19): 28301-28319 (2016-05-10)



2014

Gray E.J.; Petsalaki E.; James D.A.; Bagshaw R.D.; Stacey M.M.; Rocks O.; Gingras A.C.; Pawson T.
Src homology 2 domain containing protein 5 (SH2D5) binds the breakpoint cluster region protein, BCR, and regulates levels of Rac1-GTP*
Journal of Biological Chemistry 289 (51): 35397-35408 (2014-12-19)



2013

Froehlich C.; Grabiger S.; Schwefel D.; Faelber K.; Rosenbaum E.; Mears J.; Rocks O.; Daumke O.
Structural insights into oligomerization and mitochondrial remodelling of dynamin 1-like protein
EMBO Journal 32 (9): 1280-1292 (2013-05-02)



Schwefel D.; Arasu B.S.; Marino S.F.; Lamprecht B.; Koechert K.; Rosenbaum E.; Eichhorst J.; Wiesner B.; Behlke J.; Rocks O.; Mathas S.; Daumke O.
Structural insights into the mechanism of GTPase activation in the GIMAP family
Structure 21 (4): 550-559 (2013-04-02)



2011

Colwill K.; Graeslund S.
A roadmap to generate renewable protein binders to the human proteome
Nature Methods 8 (7): 551-558 (2011-05-15)



2010

Lorentzen A.; Kinkhabwala A.; Rocks O.; Vartak N.; Bastiaens P.I.
Regulation of Ras localization by acylation enables a mode of intracellular signal propagation
Science Signaling 3 (140): ra68 (2010-09-21)



Dekker F.J.; Rocks O.; Vartak N.; Menninger S.; Hedberg C.; Balamurugan R.; Wetzel S.; Renner S.; Gerauer M.; Schoelermann B.; Rusch M.; Kramer J.W.; Rauh D.; Coates G.W.; Brunsveld L.; Bastiaens P.I.; Waldmann H.
Small-molecule inhibition of APT1 affects Ras localization and signaling
Nature Chemical Biology 6 (6): 449-456 (2010-06)



Rocks O.; Gerauer M.; Vartak N.; Koch S.; Huang Z.P.; Pechlivanis M.; Kuhlmann J.; Brunsveld L.; Chandra A.; Ellinger B.; Waldmann H.; Bastiaens P.I.
The palmitoylation machinery is a spatially organizing system for peripheral membrane proteins
Cell 141 (3): 458-471 (2010-04-30)



2006

Verveer P.J.; Rocks O.; Harpur A.G.; Bastiaens P.I.H.
Measuring FRET by sensitized emission
Cold Spring Harbor Protocols 2006 (6): (2006-11-01)



Verveer P.J.; Rocks O.; Harpur A.G.; Bastiaens P.I.H.
An experimental setup for frequency domain FLIM
Cold Spring Harbor Protocols 2006 (6): (2006-11-01)



Verveer P.J.; Rocks O.; Harpur A.G.; Bastiaens P.I.H.
Imaging protein interactions by FRET microscopy: labeling proteins with fluorescent dyes
Cold Spring Harbor Protocols 2006 (6): (2006-11-01)



Verveer P.J.; Rocks O.; Harpur A.G.; Bastiaens P.I.H.
Imaging protein interactions by FRET microscopy: cell preparation for FRET analysis
Cold Spring Harbor Protocols 2006 (6): (2006-11-01)



Verveer P.J.; Rocks O.; Harpur A.G.; Bastiaens P.I.H.
FLIM measurements and frequency domain FLIM data analysis
Cold Spring Harbor Protocols 2006 (6): (2006-11-01)



Verveer P.J.; Rocks O.; Harpur A.G.; Bastiaens P.I.H.
Imaging protein interactions by FRET microscopy: FRET measurements by acceptor photobleaching
Cold Spring Harbor Protocols 2006 (6): (2006-11-01)



Verveer P.J.; Rocks O.; Harpur A.G.; Bastiaens P.I.H.
Imaging protein interactions by FRET microscopy: FLIM measurements
Cold Spring Harbor Protocols 2006 (6): (2006-11-01)



Verveer P.J.; Rocks O.; Harpur A.G.; Bastiaens P.I.H.
Measuring FRET by acceptor photobleaching
Cold Spring Harbor Protocols 2006 (6): (2006-11-01)



Verveer P.J.; Rocks O.; Harpur A.G.; Bastiaens P.I.H.
Imaging protein interactions by FRET microscopy: FRET measurements by sensitized emission
Cold Spring Harbor Protocols 2006 (6): (2006-11-01)



Rocks O.; Peyker A.; Bastiaens P.I.
Spatio-temporal segregation of Ras signals: one ship, three anchors, many harbors
Current Opinion in Cell Biology 18 (4): 351-357 (2006-08)



2005

Rocks O.; Peyker A.; Kahms M.; Verveer P.J.; Koerner C.; Lumbierres M.; Kuhlmann J.; Waldmann H.; Wittinghofer A.; Bastiaens P.I.
An acylation cycle regulates localization and activity of palmitoylated Ras isoforms
Science 307 (5716): 1746-1752 (2005-03-18)



Peyker A.; Rocks O.; Bastiaens P.I.
Imaging activation of two Ras isoforms simultaneously in a single cell
Chembiochem 6 (1): 78-85 (2005-01)



2004

Squire A.; Verveer P.J.; Rocks O.; Bastiaens P.I.
Red-edge anisotropy microscopy enables dynamic imaging of homo-FRET between green fluorescent proteins in cells
Journal of Structural Biology 147 (1): 62-69 (2004-07)



2003

Reynolds A.R.; Tischer C.; Verveer P.J.; Rocks O.; Bastiaens P.I.
EGFR activation coupled to inhibition of tyrosine phosphatases causes lateral signal propagation
Nature Cell Biology 5 (5): 447-453 (2003-05)



2002

Engelke M.; Friedrich O.; Budde P.; Schaefer C.; Niemann U.; Zitt C.; Juengling E.; Rocks O.; Lueckhoff A.; Frey J.
Structural domains required for channel function of the mouse transient receptor potential protein homologue TRP1beta
FEBS Letters 523 (1-3): 193-199 (2002-07-17)



1999

Bauer M.K.; Schubert A.; Rocks O.; Grimm S.
Adenine nucleotide translocase-1, a component of the permeability transition pore, can dominantly induce apoptosis
Journal of Cell Biology 147 (7): 1493-1502 (1999-12-27)