Publications



2016

Kahlfuss S.; Flieger R.R.; Mankertz A.; Yilmaz K.; Roepke T.K.
Pericardial tamponade in an adult suffering from acute mumps infection
Case Reports in Medicine 2016: 7980936 (2016-10-12)



Kahlfuss S.; Flieger R.R.; Roepke T.K.; Yilmaz K.
Diagnosis and treatment of cardiac echinococcosis
Heart 102 (17): 1348-1353 (2016-09)



Treskatsch S.; Shaqura M.; Dehe L.; Roepke T.K.; Shakibaei M.; Schaefer M.; Mousa S.A.
Evidence for MOR on cell membrane, sarcoplasmatic reticulum and mitochondria in left ventricular myocardium in rats
Heart and Vessels 31 (8): 1380-1388 (2016-08)



Lisewski U.; Koehncke C.; Wilck N.; Buschmeyer B.; Pieske B.; Roepke T.K.
Increased aldosterone-dependent Kv1.5 recycling predisposes to pacing-induced atrial fibrillation in Kcne3-/- mice
FASEB Journal 30 (7): 2476-2489 (2016-07)



Lodka D.; Pahuja A.; Geers-Knoerr C.; Scheibe R.; Nowak M.; Hamati J.; Koehncke C.; Purfuerst B.; Kanashova T.; Schmidt S.; Glass D.J.; Morano I.; Heuser A.; Kraft T.; Bassel-Duby R.; Olson E.N.; Dittmar G.; Sommer T.; Fielitz J.
Muscle RING-finger 2 and 3 maintain striated-muscle structure and function
Journal of Cachexia Sarcopenia and Muscle 7 (2): 165-180 (2016-05)



Abbott G.W.; Roepke T.K.
KCNE2 and gastric cancer: bench to bedside
Oncotarget 7 (14): 17286-17287 (2016-04-05)



Lee S.M.; Nguyen D.; Anand M.; Kant R.; Koehncke C.; Lisewski U.; Roepke T.K.; Hu Z.; Abbott G.W.
Kcne2 deletion causes early-onset nonalcoholic fatty liver disease via iron deficiency anemia
Scientific Reports 6: 23118 (2016-03-17)



Baur A.D.J.; Kunz F.; Schwenke C.; Pschowski R.; Roepke T.K.; Pavel M.; Denecke T.
Maximizing information from routine staging computed tomography in functional neuroendocrine neoplasms: are there findings indicating the presence of carcinoid heart disease?
Journal of Computer Assisted Tomography 40 (2): 277-282 (2016-03)



Treskatsch S.; Feldheiser A.; Shaqura M.; Dehe L.; Habazettl H.; Roepke T.K.; Shakibaei M.; Schaefer M.; Spies C.D.; Mousa S.A.
Cellular localization and adaptive changes of the cardiac delta opioid receptor system in an experimental model of heart failure in rats
Heart and Vessels 31 (2): 241-250 (2016-02)



2015

Treskatsch S.; Shaqura M.; Dehe L.; Feldheiser A.; Roepke T.K.; Shakibaei M.; Spies C.D.; Schaefer M.; Mousa S.A.
Upregulation of the kappa opioidergic system in left ventricular rat myocardium in response to volume overload : adaptive changes of the cardiac kappa opioid system in heart failure
Pharmacological Research 102: 33-41 (2015-12)



Treskatsch S.; Shakibaei M.; Feldheiser A.; Shaqura M.; Dehe L.; Roepke T.K.; Spies C.; Schaefer M.; Mousa S.A.
Ultrastructural changes associated with myocardial apoptosis, in failing rat hearts induced by volume overload
International Journal of Cardiology 197: 327-332 (2015-10-15)



2014

Abbott G.W; Tai K.K.; Neverisky D.L.; Hansler A.; Hu Z.; Roepke T.K.; Lerner D.J.; Chen Q.; Liu L.; Zupan B.; Toth M.; Haynes R.; Huang X.; Demirbas D.; Buccafusca R.; Gross S.S.; Kanda V.A.; Berry G.T.
KCNQ1, KCNE2, and Na(+)-coupled solute transporters form reciprocally regulating complexes that affect neuronal excitability
Science Signaling 7 (315): ra22 (2014-03-04)



Zhang K.; Lehner L.J.; Praeger D.; Baumann G.; Knebel F.; Quinkler M.; Roepke T.K.
Glucagonoma-induced acute heart failure
Endocrinology Diabetes and Metabolism Case Reports 2014: 140061 (2014)



2013

Koehncke C.; Lisewski U.; Schleussner L.; Gaertner C.; Reichert S.; Roepke T.K.
Isolation and kv channel recordings in murine atrial and ventricular cardiomyocytes
Journal of Visualized Experiments (73): e50145 (2013-03-12)



2011

Roepke T.K.; Kanda V.A.; Purtell K.; King E.C.; Lerner D.J.; Abbott G.W.
KCNE2 forms potassium channels with KCNA3 and KCNQ1 in the choroid plexus epithelium
FASEB Journal 25 (12): 4264-4273 (2011-12)



Roepke T.K.; King E.C.; Purtell K.; Kanda V.A.; Lerner D.J.; Abbott G.W.
Genetic dissection reveals unexpected influence of beta subunits on KCNQ1 K+ channel polarized trafficking in vivo
FASEB Journal 25 (2): 727-736 (2011-02)



2010

Purtell K.; Roepke T.K.; Abbott G.W.
Cardiac arrhythmia and thyroid dysfunction: a novel genetic link
International Journal of Biochemistry and Cell Biology 42 (11): 1767-1770 (2010-11)



Roepke T.K.; Purtell K.; King E.C.; La Perle K.M.; Lerner D.J.; Abbott G.W.
Targeted deletion of Kcne2 causes gastritis cystica profunda and gastric neoplasia
PLoS ONE 5 (7): e11451 (2010-07-06)



2009

Roepke T.K.; King E.C.; Reyna-Neyra A.; Paroder M.; Purtell K.; Koba W.; Fine E.; Lerner D.J.; Carrasco N.; Abbott G.W.
Kcne2 deletion uncovers its crucial role in thyroid hormone biosynthesis
Nature Medicine 15 (10): 1186-1194 (2009-10)



Xu X.; Kanda V.A.; Choi E.; Panaghie G.; Roepke T.K.; Gaeta S.A.; Christini D.J.; Lerner D.J.; Abbott G.W.
MinK-dependent internalization of the IKs potassium channel
Cardiovascular Research 82 (3): 430-438 (2009-06-01)



Abbott G.W.; Roepke T.K.
HERG biosynthesis: the positive influence of negative charge
American Journal of Physiology Heart and Circulatory Physiology 296 (5): H1211-H1212 (2009-05)



McCrossan Z.A.; Roepke T.K.; Lewis A.; Panaghie G.; Abbott G.W.
Regulation of the Kv2.1 potassium channel by MinK and MiRP1
Journal of Membrane Biology 228 (1): 1-14 (2009-03)



2008

Roepke T.K.; Kontogeorgis A.; Ovanez C.; Xu X.; Young J.B.; Purtell K.; Goldstein P.A.; Christini D.J.; Peters N.S.; Akar F.G.; Gutstein D.E.; Lerner D.J.; Abbott G.W.
Targeted deletion of kcne2 impairs ventricular repolarization via disruption of I(K,slow1) and I(to,f)
FASEB Journal 22 (10): 3648-3660 (2008-10-01)



Yang L.; Soonpaa M.H.; Adler E.D.; Roepke T.K.; Kattman S.J.; Kennedy M.; Henckaerts E.; Bonham K.; Abbott G.W.; Linden R.M.; Field L.J.; Keller G.M.
Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population
Nature 453 (7194): 524-528 (2008-05-22)



Gordon E.; Panaghie G.; Deng L.; Bee K.J.; Roepke T.K.; Krogh-Madsen T.; Christini D.J.; Ostrer H.; Basson C.T.; Chung W.; Abbott G.W.
A KCNE2 mutation in a patient with cardiac arrhythmia induced by auditory stimuli and serum electrolyte imbalance
Cardiovascular Research 77 (1): 98-106 (2008-01)



2007

Abbott G.W.; Xu X.; Roepke T.K.
Impact of ancillary subunits on ventricular repolarization
Journal of Electrocardiology 40 (6 Suppl): S42-S46 (2007-11)



2006

Roepke T.K.; Anantharam A.; Kirchhoff P.; Busque S.M.; Young J.B.; Geibel J.P.; Lerner D.J.; Abbott G.W.
The KCNE2 potassium channel ancillary subunit is essential for gastric acid secretion
Journal of Biological Chemistry 281 (33): 23740-23747 (2006-08-18)



Geibel J.; Sritharan K.; Geibel R.; Geibel P.; Persing J.S.; Seeger A.; Roepke T.K.; Deichstetter M.; Prinz C.; Cheng S.X.; Martin D.; Hebert S.C.
Calcium-sensing receptor abrogates secretagogue- induced increases in intestinal net fluid secretion by enhancing cyclic nucleotide destruction
Proceedings of the National Academy of Sciences of the United States of America 103 (25): 9390-9397 (2006-06-20)



Gordon E.; Roepke T.K.; Abbott G.W.
Endogenous KCNE subunits govern Kv2.1 K+ channel activation kinetics in Xenopus oocyte studies
Biophysical Journal 90 (4): 1223-1231 (2006-02-15)



Roepke T.K.; Abbott G.W.
Pharmacogenetics and cardiac ion channels
Vascular Pharmacology 44 (2): 90-106 (2006-02)