Publications



2017

Winterer J.; Maier N.; Wozny C.; Beed P.; Breustedt J.; Evangelista R.; Peng Y.; D'Albis T.; Kempter R.; Schmitz D.
Excitatory microcircuits within superficial layers of the medial entorhinal cortex
Cell Reports 19 (6): 1110-1116 (2017-05-09)



Willmes C.G.; Mack T.G.A.; Ledderose J.; Schmitz D.; Wozny C.; Eickholt B.J.
Investigation of hippocampal synaptic transmission and plasticity in mice deficient in the actin-binding protein Drebrin
Scientific Reports 7: 42652 (2017-02-15)



Lim C.S.; Kim H.; Yu N.K.; Kang S.J.; Kim T.H.; Ko H.G.; Lee J.; Yang J.E.; Ryu H.H.; Park T.; Gim J.; Nam H.J.; Baek S.H.; Wegener S.; Schmitz D.; Boeckers T.M.; Lee M.G.; Kim E.; Lee J.H.; Lee Y.S.; Kaang B.K.
Enhancing inhibitory synaptic function reverses spatial memory deficits in Shank2 mutant mice
Neuropharmacology 112 (Part A): 104-112 (2017-01)



2016

Klein A.S.; Donoso J.R.; Kempter R.; Schmitz D.; Beed P.
Early cortical changes in gamma oscillations in alzheimer’s disease
Frontiers in Systems Neuroscience 10: 83 (2016-10-26)



Grauel M.K.; Maglione M.; Reddy-Alla S.; Willmes C.G.; Brockmann M.M.; Trimbuch T.; Rosenmund T.; Pangalos M.; Vardar G.; Stumpf A.; Walter A.M.; Rost B.R.; Eickholt B.J.; Haucke V.; Schmitz D.; Sigrist S.J.; Rosenmund C.
RIM-binding protein 2 regulates release probability by fine-tuning calcium channel localization at murine hippocampal synapses
Proceedings of the National Academy of Sciences of the United States of America 113 (41): 11615-11620 (2016-10-11)



Kreye J.; Wenke N.K.; Chayka M.; Leubner J.; Murugan R.; Maier N.; Jurek B.; Ly L.T.; Brandl D.; Rost B.R.; Stumpf A.; Schulz P.; Radbruch H.; Hauser A.E.; Pache F.; Meisel A.; Harms L.; Paul F.; Dirnagl U.; Garner C.; Schmitz D.; Wardemann H.; Pruess H.
Human cerebrospinal fluid monoclonal N-methyl-D-aspartate receptor autoantibodies are sufficient for encephalitis pathogenesis
Brain 139 (10): 2641-2652 (2016-10-01)



Zarnadze S.; Baeuerle P.; Santos-Torres J.; Boehm C.; Schmitz D.; Geiger J.R.P.; Dugladze T.; Gloveli T.
Cell-specific synaptic plasticity induced by network oscillations
eLife 5: e14912 (2016-05-24)



Stempel A.V.; Stumpf A.; Zhang H.Y.; Oezdogan T.; Pannasch U.; Theis A.K.; Otte D.M.; Wojtalla A.; Racz I.; Ponomarenko A.; Xi Z.X.; Zimmer A.; Schmitz D.
Cannabinoid type 2 receptors mediate a cell type-specific plasticity in the hippocampus
Neuron 90 (4): 795-809 (2016-05-18)



Elagabani M.N.; Brisevac D.; Kintscher M.; Pohle J.; Koehr G.; Schmitz D.; Kornau H.C.
Subunit-selective NMDA receptor signaling through BRAG1 and BRAG2 during synapse maturation
Journal of Biological Chemistry 291 (17): 9105-9118 (2016-04-22)



Korte M.; Schmitz D.
Cellular and system biology of memory: Timing, molecules, and beyond
Physiological Reviews 96 (2): 647-693 (2016-04)



Tang Q.; Burgalossi A.; Ebbesen C.L.; Sanguinetti-Scheck J.I.; Schmidt H.; Tukker J.J.; Naumann R.; Ray S.; Preston-Ferrer P.; Schmitz D.; Brecht M.
Functional architecture of the rat parasubiculum
Journal of Neuroscience 36 (7): 2289-2301 (2016-02-17)



2015

Rost B.R.; Schneider F.; Grauel M.K.; Wozny C.; Bentz C.G.; Blessing A.; Rosenmund T.; Jentsch T.J.; Schmitz D.; Hegemann P.; Rosenmund C.
Optogenetic acidification of synaptic vesicles and lysosomes
Nature Neuroscience 18 (12): 1845-1852 (2015-12)



Boehm C.; Pangalos M.; Schmitz D.; Winterer J.
Serotonin attenuates feedback excitation onto O-LM interneurons
Cerebral Cortex 25 (11): 4572-4583 (2015-11)



Barucker C.; Bittner H.J.; Chang P.K.Y.; Cameron S.; Hancock M.A.; Liebsch F.; Hossain S.; Harmeier A.; Shaw H.; Charron F.M.; Gensler M.; Dembny P.; Zhuang W.; Schmitz D.; Rabe J.P.; Rao Y.; Lurz R.; Hildebrand P.W.; McKinney R.A.; Multhaup G.
A{beta}42-oligomer Interacting Peptide (AIP) neutralizes toxic amyloid-{beta}42 species and protects synaptic structure and function
Scientific Reports 5: 15410 (2015-10-29)



Boehm C.; Peng Y.; Maier N.; Winterer J.; Poulet J.F.A.; Geiger J.R.P.; Schmitz D.
Functional diversity of subicular principal cells during hippocampal ripples
Journal of Neuroscience 35 (40): 13608-13618 (2015-10-07)



Wu Y.J.; Tejero R.; Arancillo M.; Vardar G.; Korotkova T.; Kintscher M.; Schmitz D.; Ponomarenko A.; Tabares L.; Rosenmund C.
Syntaxin 1B is important for mouse postnatal survival and proper synaptic function at the mouse neuromuscular junctions
Journal of Neurophysiology 114 (4): 2404-2417 (2015-10-01)



Tang Q.; Ebbesen C.L.; Sanguinetti-Scheck J.I.; Preston-Ferrer P.; Gundlfinger A.; Winterer J.; Beed P.; Ray S.; Naumann R.; Schmitz D.; Brecht M.; Burgalossi A.
Anatomical organization and spatiotemporal firing patterns of layer 3 neurons in the rat medial entorhinal cortex
Journal of Neuroscience 35 (36): 12346-12354 (2015-09-09)



Johenning F.W.; Theis A.K.; Pannasch U.; Rueckl M.; Ruediger S.; Schmitz D.
Ryanodine receptor activation induces long-term plasticity of spine calcium dynamics
PLoS Biology 13 (6): e1002181 (2015-06-22)



Ritter P.; Born J.; Brecht M.; Dinse H.R.; Heinemann U.; Pleger B.; Schmitz D.; Schreiber S.; Villringer A.; Kempter R.
State-dependencies of learning across brain scales
Frontiers in Computational Neuroscience 9: 1 (2015-02-26)



Fidzinski P.; Korotkova T.; Heidenreich M.; Maier N.; Schuetze S.; Kobler O.; Zuschratter W.; Schmitz D.; Ponomarenko A.; Jentsch T.J.
KCNQ5 K(+) channels control hippocampal synaptic inhibition and fast network oscillations
Nature Communications 6: 6254 (2015-02-04)



2014

Schmitz D.; Breustedt J.; Gundlfinger A.
Retrograde signaling causes excitement
Neuron 81 (4): 717-719 (2014-02-19)



2013

Beed P.; Gundlfinger A.; Schneiderbauer S.; Song J.; Boehm C.; Burgalossi A.; Brecht M.; Vida I.; Schmitz D.
Inhibitory gradient along the dorsoventral axis in the medial entorhinal cortex
Neuron 79 (6): 1197-1207 (2013-09-18)



Kintscher M.; Wozny C.; Johenning F.W.; Schmitz D.; Breustedt J.
Role of RIM1{alpha} in short- and long-term synaptic plasticity at cerebellar parallel fibres
Nature Communications 4: 2392 (2013-09-03)



Ohlraun S.; Wollersheim T.; Weiss C.; Martus P.; Weber-Carstens S.; Schmitz D.; Schuelke M.
CARbon DIoxide for the treatment of Febrile seizures: rationale, feasibility, and design of the CARDIF-study
Journal of Translational Medicine 11: 157 (2013-06-27)



Pangalos M.; Donoso J.R.; Winterer J.; Zivkovic A.R.; Kempter R.; Maier N.; Schmitz D.
Recruitment of oriens-lacunosum-moleculare interneurons during hippocampal ripples
Proceedings of the National Academy of Sciences of the United States of America 110 (11): 4398-4403 (2013-03-12)



Maier N.; Draguhn A.; Schmitz D.; Both M.
Fast network oscillations in the hippocampus: phenomena, mechanisms and open questions between cellular and systemic neurosciences
e-Neuroforum 4 (1): 1-10 (2013-03)



Kononenko N.L.; Diril M.K.; Puchkov D.; Kintscher M.; Koo S.J.; Pfuhl G.; Winter Y.; Wienisch M.; Klingauf J.; Breustedt J.; Schmitz D.; Maritzen T.; Haucke V.
Compromised fidelity of endocytic synaptic vesicle protein sorting in the absence of stonin 2
Proceedings of the National Academy of Sciences of the United States of America 110 (6): E526-E535 (2013-02-05)



Maier N.; Draguhn A.; Schmitz D.; Both M.
Schnelle Netzwerkoszillationen im Hippocampus - Phaenomene, Mechanismen und offene Fragen zwischen zellulaeren und systemischen Neurowissenschaften [Rapid network-oscillations in the hippocampus - phenomena, mechanisms and open questions between cellular and systemic neurosciences]
Neuroforum 19 (1): 3-13 (2013-02)



Roesner J.; Liotta A.; Schmitz D.; Heinemann U.; Kovacs R.
A LED-based method for monitoring NAD(P)H and FAD fluorescence in cell cultures and brain slices
Journal of Neuroscience Methods 212 (2): 222-227 (2013-01-30)



2012

Liotta A.; Roesner J.; Huchzermeyer C.; Wojtowicz A.; Kann O.; Schmitz D.; Heinemann U.; Kovacs R.
Energy demand of synaptic transmission at the hippocampal Schaffer-collateral synapse
Journal of Cerebral Blood Flow and Metabolism 32 (11): 2076-2083 (2012-11)



Kintscher M.; Breustedt J.; Miceli S.; Schmitz D.; Wozny C.
Group II metabotropic glutamate receptors depress synaptic transmission onto subicular burst firing neurons
PLoS ONE 7 (9): e45039 (2012-09-11)



Traub R.D.; Schmitz D.; Maier N.; Whittington M.A.; Draguhn A.
Axonal properties determine somatic firing in a model of in vitro CA1 hippocampal sharp wave/ripples and persistent gamma oscillations
European Journal of Neuroscience 36 (5): 2650-2660 (2012-09)



Kaden D.; Harmeier A.; Weise C.; Munter L.M.; Althoff V.; Rost B.R.; Hildebrand P.W.; Schmitz D.; Schaefer M.; Lurz R.; Skodda S.; Yamamoto R.; Arlt S.; Finckh U.; Multhaup G.
Novel APP/A{beta} mutation K16N produces highly toxic heteromeric A{beta} oligomers
EMBO Molecular Medicine 4 (7): 647-659 (2012-07)



Dugladze T.; Schmitz D.; Whittington M.A.; Vida I.; Gloveli T.
Segregation of axonal and somatic activity during fast network oscillations
Science 336 (6087): 1458-1461 (2012-06-15)



Maier N.; Morris G.; Schuchmann S.; Korotkova T.; Ponomarenko A.; Boehm C.; Wozny C.; Schmitz D.
Cannabinoids disrupt hippocampal sharp wave-ripples via inhibition of glutamate release
Hippocampus 22 (6): 1350-1362 (2012-06)



Pruess H.; Hoeltje M.; Maier N.; Gomez A.; Buchert R.; Harms L.; Ahnert-Hilger G.; Schmitz D.; Terborg C.; Kopp U.; Klingbeil C.; Probst C.; Kohler S.; Schwab J.M.; Stoecker W.; Dalmau J.; Wandinger K.P.
IgA NMDA receptor antibodies are markers of synaptic immunity in slow cognitive impairment
Neurology 78 (22): 1743-1753 (2012-05-29)



Schmeisser M.J.; Ey E.; Wegener S.; Bockmann J.; Stempel A.V.; Kuebler A.; Janssen A.L.; Udvardi P.T.; Shiban E.; Spilker C.; Balschun D.; Skryabin B.V.; Dieck S.t.; Smalla K.H.; Montag D.; Leblond C.S.; Faure P.; Torquet N.; Le Sourd A.M.; Toro R.; Grabrucker A.M.; Shoichet S.A.; Schmitz D.; Kreutz M.R.; Bourgeron T.; Gundelfinger E.D.; Boeckers T.M.
Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2
Nature 486 (7402): 256-260 (2012-04-29)



Vogt J.; Glumm R.; Schlueter L.; Schmitz D.; Rost B.R.; Streu N.; Rister B.; Suman Bharathi B.; Gagiannis D.; Hildebrandt H.; Weinhold B.; Muehlenhoff M.; Naumann T.; Savaskan N.E.; Brauer A.U.; Reutter W.; Heimrich B.; Nitsch R.; Horstkorte R.
Homeostatic regulation of NCAM polysialylation is critical for correct synaptic targeting
Cellular and Molecular Life Sciences 69 (7): 1179-1191 (2012-04)



Salmen B.; Beed P.S.; Ozdogan T.; Maier N.; Johenning F.W.; Winterer J.; Breustedt J.; Schmitz D.
GluK1 inhibits calcium dependent and independent transmitter release at associational/commissural synapses in area CA3 of the hippocampus
Hippocampus 22 (1): 57-68 (2012-01)



2011

Liu K.S.Y.; Siebert M.; Mertel S.; Knoche E.; Wegener S.; Wichmann C.; Matkovic T.; Muhammad K.; Depner H.; Mettke C.; Bueckers J.; Hell S.W.; Mueller M.; Davis G.W.; Schmitz D.; Sigrist S.J.
RIM-binding protein, a central part of the active zone, is essential for neurotransmitter release
Science 334 (6062): 1565-1659 (2011-12-16)



Schuchmann S.; Hauck S.; Henning S.; Grueters-Kieslich A.; Vanhatalo S.; Schmitz D.; Kaila K.
Respiratory alkalosis in children with febrile seizures
Epilepsia 52 (11): 1949-1955 (2011-11)



Maier N.; Tejero-Cantero A.; Dorrn A.L.; Winterer J.; Beed P.S.; Morris G.; Kempter R.; Poulet J.F.A.; Leibold C.; Schmitz D.
Coherent phasic excitation during hippocampal ripples
Neuron 72 (1): 137-152 (2011-10-06)



Rost B.R.; Nicholson P.; Ahnert-Hilger G.; Rummel A.; Rosenmund C.; Breustedt J.; Schmitz D.
Activation of metabotropic GABA receptors increases the energy barrier for vesicle fusion
Journal of Cell Science 124 (Pt 18): 3066-3073 (2011-09-15)



Baehner F.; Weiss E.K.; Birke G.; Maier N.; Schmitz D.; Rudolph U.; Frotscher M.; Traub R.D.; Both M.; Draguhn A.
Cellular correlate of assembly formation in oscillating hippocampal networks in vitro
Proceedings of the National Academy of Sciences of the United States of America 108 (35): E607-E616 (2011-08-30)



Wiegand H.F.; Beed P.; Bendels M.H.; Leibold C.; Schmitz D.; Johenning F.W.
Complementary sensory and associative microcircuitry in primary olfactory cortex
Journal of Neuroscience 31 (34): 12149-12158 (2011-08-24)



Winterer J.; Stempel A.V.; Dugladze T.; Foeldy C.; Maziashvili N.; Zivkovic A.R.; Priller J.; Soltesz I.; Gloveli T.; Schmitz D.
Cell-type-specific modulation of feedback inhibition by serotonin in the hippocampus
Journal of Neuroscience 31 (23): 8464-8475 (2011-06-08)



Heisler F.F.; Loebrich S.; Pechmann Y.; Maier N.; Zivkovic A.R.; Tokito M.; Hausrat T.J.; Schweizer M.; Baehring R.; Holzbaur E.L.; Schmitz D.; Kneussel M.
Muskelin regulates actin filament- and microtubule-based GABA(A) receptor transport in neurons
Neuron 70 (1): 66-81 (2011-04-14)



Sigrist S.J.; Schmitz D.
Structural and functional plasticity of the cytoplasmic active zone
Current Opinion in Neurobiology 21 (1): 144-150 (2011-02)



2010

Beed P.; Bendels M.H.K.; Wiegand H.F.; Leibold C.; Johenning F.W.; Schmitz D.
Analysis of excitatory microcircuitry in the medial entorhinal cortex reveals cell-type-specific differences
Neuron 68 (6): 1059-1066 (2010-12-22)



Bendels M.H.K.; Beed P.; Schmitz D.; Johenning F.W.; Leibold C.
Detection of input sites in scanning photostimulation data based on spatial correlations
Journal of Neuroscience Methods 192 (2): 286-295 (2010-10-15)



Schapitz I.U.; Behrend B.; Pechmann Y.; Lappe-Siefke C.; Kneussel S.J.; Wallace K.E.; Stempel A.V.; Buck F.; Grant S.G.N.; Schweizer M.; Schmitz D.; Schwarz J.R.; Holzbaur E.L.F.; Kneussel M.
Neuroligin 1 is dynamically exchanged at postsynaptic sites
Journal of Neuroscience 30 (38): 12733-12744 (2010-09-22)



Rost B.R.; Breustedt J.; Schoenherr A.; Grosse G.; Ahnert-Hilger G.; Schmitz D.
Autaptic cultures of single hippocampal granule cells of mice and rats
European Journal of Neuroscience 32 (6): 939-947 (2010-09)



Breustedt J; Gundlfinger A; Varoqueaux F; Reim K; Brose N; Schmitz D.
Munc13-2 differentially affects hippocampal synaptic transmission and plasticity
Cerebral Cortex 20 (5): 1109-1120 (2010-05)



Gundlfinger A.; Breustedt J.; Sullivan D.; Schmitz D.
Natural spike trains trigger short- and long-lasting dynamics at hippocampal mossy fiber synapses in rodents
PLoS ONE 5 (4): e9961 (2010-04-01)



Wirth E.K.; Conrad M.; Winterer J.; Wozny C.; Carlson B.A.; Roth S.; Schmitz D.; Bornkamm G.W.; Coppola V.; Tessarollo L.; Schomburg L.; Koehrle J.; Hatfield D.L.; Schweizer U.
Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration
FASEB Journal 24 (3): 844-852 (2010-03)



2009

Behr J.; Wozny C.; Fidzinski P.; Schmitz D.
Synaptic plasticity in the subiculum
Progress in Neurobiology 89 (4): 334-342 (2009-12-10)



Kalus I.; Salmen B.; Viebahn C.; von Figura K.; Schmitz D.; D'Hooge R.; Dierks T.
Differential involvement of the extracellular 6-O-endosulfatases Sulf1 and Sulf2 in brain development and neuronal and behavioural plasticity
Journal of Cellular and Molecular Medicine 13 (11-12): 4505-4521 (2009-11)



Johenning F.W.; Beed P.S.; Trimbuch T.; Bendels M.H.K.; Winterer J.; Schmitz D.
Dendritic compartment and neuronal output mode determine pathway-specific long-term potentiation in the piriform cortex
Journal of Neuroscience 29 (43): 13649-13661 (2009-10-28)



Schmidt R.; Diba K.; Leibold C.; Schmitz D.; Buzsaki G.; Kempter R.
Single-trial phase precession in the hippocampus
Journal of Neuroscience 29 (42): 13232-13241 (2009-10-21)



Trimbuch T.; Beed P.; Vogt J.; Schuchmann S.; Maier N.; Kintscher M.; Breustedt J.; Schuelke M.; Streu N.; Kieselmann O.; Brunk I.; Laube G.; Strauss U.; Battefeld A.; Wende H.; Birchmeier C.; Wiese S.; Sendtner M.; Kawabe H.; Kishimoto-Suga M.; Brose N.; Baumgart J.; Geist B.; Aoki J.; Savaskan N.E.; Braeuer A.U.; Chun J.; Ninnemann O.; Schmitz D.; Nitsch R.
Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling
Cell 138 (6): 1222-12235 (2009-09-18)



Maier N.; Morris G.; Johenning F.W.; Schmitz D.
An approach for reliably investigating hippocampal sharp wave-ripples in vitro
PLoS ONE 4 (9): e6925 (2009-09-07)



Harmeier A.; Wozny C.; Rost B.R.; Munter L.M.; Hua H.; Georgiev O.; Beyermann M.; Hildebrand P.W.; Weise C.; Schaffner W.; Schmitz D.; Multhaup G.
Role of amyloid-{beta} glycine 33 in oligomerization, toxicity, and neuronal plasticity
Journal of Neuroscience 29 (23): 7582-7590 (2009-06-10)



Beed P.S.; Salmen B.; Schmitz D.
GluK2-mediated excitability within the superficial layers of the entorhinal cortex
PLoS ONE 4 (5): e5576 (2009-05-18)



Wozny C.; Breustedt J.; Wolk F.; Varoqueaux F.; Boretius S.; Zivkovic A.R.; Neeb A.; Frahm J.; Schmitz D.; Brose N.; Ivanovic A.
The function of glutamatergic synapses is not perturbed by severe knockdown of 4.1N and 4.1G expression
Journal of Cell Science 122 (Pt 5): 735-744 (2009-03-01)



2008

Wozny C.; Maier N.; Fidzinski P.; Breustedt J.; Behr J.; Schmitz D.
Differential cAMP signaling at hippocampal output synapses
Journal of Neuroscience 28 (53): 14358-14362 (2008-12-31)



Bendels M.H.K.; Beed P.; Leibold C.; Schmitz D.; Johenning F.W.
A novel control software that improves the experimental workflow of scanning photostimulation experiments
Journal of Neuroscience Methods 175 (1): 44-57 (2008-10-30)



Wozny C.; Maier N.; Schmitz D.; Behr J.
Two different forms of long-term potentiation at CA1-subiculum synapses
Journal of Physiology 586 (Pt 11): 2725-2734 (2008-06-01)



Rohe M.; Carlo A.S.; Breyhan H.; Sporbert A.; Militz D.; Schmidt V.; Wozny C.; Harmeier A.; Erdmann B.; Bales K.R.; Wolf S.A.; Kempermann G.; Paul S.M.; Schmitz D.; Bayer T.A.; Willnow T.E.; Andersen O.M.
Sortilin-related receptor with A-type repeats (SORLA) affects the amyloid precursor protein-dependent stimulation of ERK signaling and adult neurogenesis
Journal of Biological Chemistry 283 (21): 14826-14834 (2008-05-23)



Thurley K.; Leibold C.; Gundlfinger A.; Schmitz D.; Kempter R.
Phase precession through synaptic facilitation
Neural Computation 20 (5): 1285-1324 (2008-05)



Leibold C.; Gundlfinger A.; Schmidt R.; Thurley K.; Schmitz D.; Kempter R.
Temporal compression mediated by short-term synaptic plasticity
Proceedings of the National Academy of Sciences of the United States of America 105 (11): 4417-4422 (2008-03-18)



Brecht M.; Schmitz D.
Neuroscience : Rules of plasticity
Science 319 (5859): 39-40 (2008-01-04)



2007

Gundlfinger A.; Leibold C.; Gebert K.; Moisel M.; Schmitz D.; Kempter R.
Differential modulation of short-term synaptic dynamics by long-term potentiation at mouse hippocampal mossy fibre synapses
Journal of Physiology 585 (Pt 3): 853-865 (2007-12-15)



Motazacker M.M.; Rost B.R.; Hucho T.; Garshasbi M.; Kahrizi K.; Ullmann R.; Abedini S.S.; Nieh S.E.; Amini S.H.; Goswami C.; Tzschach A.; Jensen L.R.; Schmitz D.; Ropers H.H.; Najmabadi H.; Kuss A.W.
A defect in the ionotropic glutamate receptor 6 gene (GRIK2) is associated with autosomal recessive mental retardation
American Journal of Human Genetics 81 (4): 792-798 (2007-10)



Gundlfinger A.; Bischofberger J.; Johenning F.W.; Torvinen M.; Schmitz D.; Breustedt J.
Adenosine modulates transmission at the hippocampal mossy fibre synapse via direct inhibition of presynaptic calcium channels
Journal of Physiology 582 (Pt 1): 263-277 (2007-07-01)



Kehrer C.; Dugladze T.; Maziashvili N.; Wojtowicz A.; Schmitz D.; Heinemann U.; Gloveli T.
Increased inhibitory input to CA1 pyramidal cells alters hippocampal gamma frequency oscillations in the MK-801 model of acute psychosis
Neurobiology of Disease 25 (3): 545-552 (2007-03)



Stief F.; Zuschratter W.; Hartmann K.; Schmitz D.; Draguhn A.
Enhanced synaptic excitation-inhibition ratio in hippocampal interneurons of rats with temporal lobe epilepsy
European Journal of Neuroscience 25 (2): 519-528 (2007-01)



2006

Plath N.; Ohana O.; Dammermann B.; Errington M.L.; Schmitz D.; Gross C.; Mao X.; Engelsberg A.; Mahlke C.; Welzl H.; Kobalz U.; Stawrakakis A.; Fernandez E.; Waltereit R.; Bick-Sander A.; Therstappen E.; Cooke S.F.; Blanquet V.; Wurst W.; Salmen B.; Boesl M.R.; Lipp H.P.; Grant S.G.N.; Bliss T.V.P.; Wolfer D.P.; Kuhl D.
Arc/Arg3.1 is essential for the consolidation of synaptic plasticity and memories
Neuron 52 (3): 437-444 (2006-11-09)



Schuchmann S.; Schmitz D.; Rivera C.; Vanhatalo S.; Salmen B.; Mackie K.; Sipilae S.T.; Voipio J.; Kaila K.
Experimental febrile seizures are precipitated by a hyperthermia-induced respiratory alkalosis
Nature Medicine 12 (7): 817-823 (2006-07)



2005

Nicoll R.A.; Schmitz D.
Synaptic plasticity at hippocampal mossy fibre synapses
Nature Reviews Neuroscience 6 (11): 863-876 (2005-11)



Gundlfinger A.; Schmitz D.
Inactivity sets XL synapses in motion
Neuron 47 (5): 623-625 (2005-09-01)



Stief F.; Piechotta A.; Gabriel S.; Schmitz D.; Draguhn A.
Functional GABA uptake at inhibitory synapses in CA1 of chronically epileptic rats
Epilepsy Research 66 (1-3): 199-202 (2005-08)



Nimmrich V.; Maier N.; Schmitz D.; Draguhn A.
Induced sharp wave-ripple complexes in the absence of synaptic inhibition in mouse hippocampal slices
Journal of Physiology 563 (Pt 3): 663-670 (2005-03-15)



2004

Iserhot C.; Gebhardt C.; Schmitz D.; Heinemann U.
Glutamate transporters and metabotropic receptors regulate excitatory neurotransmission in the medial entorhinal cortex of the rat
Brain Research 1027 (1-2): 151-160 (2004-11-19)



Breustedt J.; Schmitz D.
Assessing the role of GLUK5 and GLUK6 at hippocampal mossy fiber synapses
Journal of Neuroscience 24 (45): 10093-10098 (2004-11-10)



Breustedt J.; Schmitz D.; Heinemann U.; Schmieden V.
Characterization of the inhibitory glycine receptor on entorhinal cortex neurons
European Journal of Neuroscience 19 (7): 1987-1991 (2004-04)



2003

Moore K.A.; Nicoll R.A.; Schmitz D.
Adenosine gates synaptic plasticity at hippocampal mossy fiber synapses
Proceedings of the National Academy of Sciences of the United States of America 100 (24): 14397-14402 (2003-11-25)



Breustedt J.; Vogt K.E.; Miller R.J.; Nicoll R.A.; Schmitz D.
{alpha}1E-containing Ca2+ channels are involved in synaptic plasticity
Proceedings of the National Academy of Sciences of the United States of America 100 (21): 12450-12455 (2003-10-14)



Schmitz D.; Mellor J.; Breustedt J.; Nicoll R.A.
Presynaptic kainate receptors impart an associative property to hippocampal mossy fiber long-term potentiation
Nature Neuroscience 6 (10): 1058-1063 (2003-10)



2002

Mellor J.; Nicoll R.A.; Schmitz D.
Mediation of hippocampal mossy fiber long-term potentiation by presynaptic Ih channels
Science 295 (5552): 143-147 (2002-01-04)



Chaudhry F.A.; Schmitz D.; Reimer R.J.; Larsson P.; Gray A.T.; Nicoll R.; Kavanaugh M.; Edwards R.H.
Glutamine uptake by neurons: interaction of protons with system a transporters
Journal of Neuroscience 22 (1): 62-72 (2002-01-01)



Traub R.D.; Draguhn A.; Whittington M.A.; Baldeweg T.; Bibbig A.; Buhl E.H.; Schmitz D.
Axonal gap junctions between principal neurons: a novel source of network oscillations, and perhaps epileptogenesis
Reviews in the Neurosciences 13 (1): 1-30 (2002)



2001

Schmitz D.; Mellor J.; Frerking M.; Nicoll R.A.
Presynaptic kainate receptors at hippocampal mossy fiber synapses
Proceedings of the National Academy of Sciences of the United States of America 98 (20): 11003-11008 (2001-09-25)



Schmitz D.; Schuchmann S.; Fisahn A.; Draguhn A.; Buhl E.H.; Petrasch-Parwez E.; Dermietzel R.; Heinemann U.; Traub R.D.
Axo-axonal coupling. a novel mechanism for ultrafast neuronal communication
Neuron 31 (5): 831-840 (2001-09-13)



Frerking M.; Schmitz D.; Zhou Q.; Johansen J.; Nicoll R.A.
Kainate receptors depress excitatory synaptic transmission at CA3-->CA1 synapses in the hippocampus via a direct presynaptic action
Journal of Neuroscience 21 (9): 2958-2966 (2001-05-01)



Stenkamp K.; Palva J.M.; Uusisaari M.; Schuchmann S.; Schmitz D.; Heinemann U.; Kaila K.
Enhanced temporal stability of cholinergic hippocampal {gamma} oscillations following respiratory alkalosis in vitro
Journal of Neurophysiology 85 (5): 2063-2069 (2001-05)



Schmitz D.; Mellor J.; Nicoll R.A.
Presynaptic kainate receptor mediation of frequency facilitation at hippocampal mossy fiber synapses
Science 291 (5510): 1972-1976 (2001-03-09)



Traub R.D.; Bibbig R.; Piechotta A.; Draguhn R.; Schmitz D.
Synaptic and nonsynaptic contributions to giant ipsps and ectopic spikes induced by 4-aminopyridine in the hippocampus in vitro
Journal of Neurophysiology 85 (3): 1246-1256 (2001-03)



Gloveli T.; Dugladze T.; Schmitz D.; Heinemann U.
Properties of entorhinal cortex deep layer neurons projecting to the rat dentate gyrus
European Journal of Neuroscience 13 (2): 413-420 (2001-01)



2000

Nicoll R.A.; Mellor J.; Frerking M.; Schmitz D.
Kainate receptors and synaptic plasticity
Nature 406 (6799): 957 (2000-08-31)



Schmitz D.; Frerking M.; Nicoll R.A.
Synaptic activation of presynaptic kainate receptors on hippocampal mossy fiber synapses
Neuron 27 (2): 327-338 (2000-08)



Behr J.; Gloveli T.; Schmitz D.; Heinemann U.
Dopamine depresses excitatory synaptic transmission onto rat subicular neurons via presynaptic D1-like dopamine receptors
Journal of Neurophysiology 84 (1): 112-119 (2000-07)



Draguhn A.; Traub R.D.; Bibbig A.; Schmitz D.
Ripple (approximately 200-Hz) oscillations in temporal structures
Journal of clinical neurophysiology 17 (4): 361-376 (2000-07)



Heinemann U.; Schmitz D.; Eder C.; Gloveli T.
Properties of entorhinal cortex projection cells to the hippocampal formation
Annals of the New York Academy of Sciences 911: 112-126 (2000-06)



Nicoll R.A.; Frerking M.; Schmitz D.
AMPA receptors jump the synaptic cleft
Nature Neuroscience 3 (6): 527-529 (2000-06)



Behr J.; Gloveli T.; Schmitz D.; Heinemann U.
Dopamine depresses polysynaptic inhibition in rat subicular neurons
Brain Research 861 (1): 160-164 (2000-04-07)



1999

Hetka R.; Rundfeldt C.; Heinemann U.; Schmitz D.
Retigabine strongly reduces repetitive firing in rat entorhinal cortex
European Journal of Pharmacology 386 (2-3): 165-171 (1999-12-15)



Gloveli T.; Egorov A.V.; Schmitz D.; Heinemann U.; Mueller W.
Carbachol-induced changes in excitability and [Ca2+]i signalling in projection cells of medial entorhinal cortex layers II and III
European Journal of Neuroscience 11 (10): 3626-3636 (1999-10)



Schmitz D.; Gloveli T.; Empson R.M.; Heinemann U.
Potent depression of stimulus evoked field potential responses in the medial entorhinal cortex by serotonin
British Journal of Pharmacology 128 (1): 248-254 (1999-09)



Traub R.D.; Schmitz D.; Jefferys J.G.R.; Draguhn A.
High-frequency population oscillations are predicted to occur in hippocampal pyramidal neuronal networks interconnected by axoaxonal gap junctions
Neuroscience 92 (2): 407-426 (1999-05)



1998

Schmitz D.; Gloveli T.; Empson R.M.; Heinemann U.
Comparison of the effects of serotonin in the hippocampus and the entorhinal cortex
Molecular Neurobiology 17 (1-3): 59-72 (1998-12)



Engel D.; Schmitz D.; Gloveli T.; Frahm C.; Heinemann U.; Draguhn A.
Laminar difference in GABA uptake and GAT-1 expression in rat CA1
Journal of Physiology 512 (Pt 3): 643-649 (1998-11-01)



Stenkamp K.; Heinemann U.; Schmitz D.
Dopamine suppresses stimulus-induced field potentials in layer III of rat medial entorhinal cortex
Neuroscience Letters 255 (2): 119-121 (1998-10-16)



Burg M.; Heinemann U.; Schmitz D.
Neuroactive steroids induce GABA(A) receptor-mediated depolarizing postsynaptic potentials in hippocampal CA1 pyramidal cells of the rat
European Journal of Neuroscience 10 (9): 2880-2886 (1998-09)



Gloveli T.; Schmitz D.; Heinemann U.
Interaction between superficial layers of the entorhinal cortex and the hippocampus in normal and epileptic temporal lobe
Epilepsy Research 32 (1-2): 183-193 (1998-09)



Schmitz D.; Gloveli T.; Empson R.M.; Heinemann U.
Serotonin reduces polysynaptic inhibition via 5-HT1A receptors in the superficial entorhinal cortex
Journal of Neurophysiology 80 (3): 1116-1121 (1998-09)



Schmitz D.; Gloveli T.; Behr J.; Dugladze T.; Heinemann U.
Subthreshold membrane potential oscillations in neurons of deep layers of the entorhinal cortex
Neuroscience 85 (4): 999-1004 (1998-08)



Draguhn A.; Traub R.D.; Schmitz D.; Jefferys J.G.R.
Electrical coupling underlies high-frequency oscillations in the hippocampus in vitro
Nature 394 (6689): 189-192 (1998-07-09)



Schmitz D.; Gloveli T.; Empson R.M.; Draguhn A.; Heinemann U.
Serotonin reduces synaptic excitation in the superficial medial entorhinal cortex of the rat via a presynaptic mechanism
Journal of Physiology 508 (Pt 1): 119-129 (1998-04-01)



Sokolova S.; Schmitz D.; Zhang C.L.; Loescher W.; Heinemann U.
Comparison of effects of valproate and trans-2-en-valproate on different forms of epileptiform activity in rat hippocampal and temporal cortex slices
Epilepsia 39 (3): 251-258 (1998-03)



1997

Gloveli T.; Schmitz D.; Empson R.M.; Heinemann U.
Frequency-dependent information flow from the entorhinal cortex to the hippocampus
Journal of Neurophysiology 78 (6): 3444-3449 (1997-12)



Behr J.; Empson R.M.; Schmitz D.; Gloveli T.; Heinemann U.
Effects of serotonin on synaptic and intrinsic properties of rat subicular neurons in vitro
Brain Research 773 (1-2): 217-222 (1997-10-31)



Gloveli T.; Schmitz D.; Heinemann U.
Prolonged inhibitory potentials in layer III projection cells of the rat medial entorhinal cortex induced by synaptic stimulation in vitro
Neuroscience 80 (1): 119-131 (1997-09)



Gloveli T.; Schmitz D.; Empson R.M.; Dugladze T.; Heinemann U.
Morphological and electrophysiological characterization of layer III cells of the medial entorhinal cortex of the rat
Neuroscience 77 (3): 629-648 (1997-04)



Alici K.; Gloveli T.; Schmitz D.; Heinemann U.
Effects of glutamate receptor agonists and antagonists on Ca2+ uptake in rat hippocampal slices lesioned by glucose deprivation or by kainate
Neuroscience 77 (1): 97-109 (1997-03)



Gloveli T.; Iserhot C.; Schmitz D.; Castren E.; Behr J.; Heinemann U.
Systemic administration of the phencyclidine compound MK-801 affects stimulus-induced field potentials selectively in layer III of rat medial entorhinal cortex
Neuroscience Letters 221 (2-3): 93-96 (1997-01-17)



Schmitz D.; Empson R.M.; Gloveli T.; Heinemann U.
Serotonin blocks different patterns of low Mg2+-induced epileptiform activity in rat entorhinal cortex, but not hippocampus
Neuroscience 76 (2): 449-458 (1997-01)



1996

Behr J.; Empson R.M.; Schmitz D.; Gloveli T.; Heinemann U.
Electrophysiological properties of rat subicular neurons in vitro
Neuroscience Letters 220 (1): 41-44 (1996-12-06)



1995

Schmitz D.; Empson R.M.; Heinemann U.
Serotonin and 8-OH-DPAT reduce excitatory transmission in rat hippocampal area CA1 via reduction in presumed presynaptic Ca2+ entry
Brain Research 701 (1-2): 249-254 (1995-12-01)



Schmitz D.; Gloveli T.; Heinemann U.
Effects of losigamone on synaptic potentials and spike frequency habituation in rat entorhinal cortex and hippocampal CA1 neurones
Neuroscience Letters 200 (2): 141-143 (1995-11-17)



Schmitz D.; Empson R.M.; Heinemann U.
Serotonin reduces inhibition via 5-HT1A receptors in area CA1 of rat hippocampal slices in vitro
Journal of Neuroscience 15 (11): 7217-7225 (1995-11)



Empson R.M.; Gloveli T.; Schmitz D.; Heinemann U.
Electrophysiology and morphology of a new type of cell within layer II of the rat lateral entorhinal cortex in vitro
Neuroscience Letters 193 (3): 149-152 (1995-07-07)



Schmitz D.; Empson R.M.; Gloveli T.; Heinemann U.
Serotonin reduces synaptic excitation of principal cells in the superficial layers of rat hippocampal-entorhinal cortex combined slices
Neuroscience Letters 190 (1): 37-40 (1995-04-28)



Schmitz D.; Zhang C.L.; Chatterjee S.S.; Heinemann U.
Effects of methysticin on three different models of seizure like events studied in rat hippocampal and entorhinal cortex slices
Naunyn-Schmiedeberg's archives of pharmacology 351 (4): 348-355 (1995-04)