No 3 / February 13, 2017

Inducing an identity crisis in liver cells may help diabetics

First successful reprogramming of liver cells to pancreas progenitor cells based on a single factor

It is now possible to reprogram cells from the liver into the precursor cells that give rise to the pancreas by altering the activity of a single gene. A team of researchers at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) has now accomplished this feat in mice. Their results should make it feasible to help diabetic patients through cell therapy.

No 2 / January 26, 2017

A cellular system makes the battle against a rare disease personal

Some diseases are untreatable because we lack a model system to fully understand symptoms or test possible drugs. This is the case of mitochondrial disease, a rare condition caused by defects in the “cellular powerhouse.” Scientists from the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) have now developed a new personalized strategy to address mitochondrial disease by reprogramming the patients' cells and used it to identify a promising potential drug.

No. 1 / January 23, 2017

Berlin-Buch: NAKO Health Study investigates its 5000th participant

The Berlin-Nord Study Centre has now recruited half of the 10,000 volunteers for Germany’s largest ever cohort study. Across Germany, a total of 200,000 people will participate in the study, who will be carefully examined and thereafter observed for twenty to thirty years. The large-scale study will serve the improvement of prevention, early detection and treatment of widespread diseases.