List of publications containing data obtained at ALM equipment and with support of ALM team



2017

Sawamiphak S.; Kontarakis Z.; Filosa A.; Reischauer S.; Stainier D.Y.R.
Transient cardiomyocyte fusion regulates cardiac development in zebrafish
Nature Communications 8 (1): 1525 (2017-11-15)



Hadar R.; Dong L.; Del-Valle-Anton L.; Gueneykaya D.; Voget M.; Edemann-Callesen H.; Schweibold R.; Djodari-Irani A.; Goetz T.; Ewing S.; Kettenmann H.; Wolf S.A.; Winter C.
Deep brain stimulation during early adolescence prevents microglial alterations in a model of maternal immune activation
Brain, Behavior and Immunity 63: 71-80 (2017-07-07)



Xu K.; Rosenstiel P.; Paragas N.; Hinze C.; Gao X.; Huai Shen T.; Werth M.; Forster C.; Deng R.; Bruck E.; Boles R.W.; Tornato A.; Gopal T.; Jones M.; Konig Ju.; Stauber J.; D'Agati V.; Erdjument-Bromage H.; Saggi S.; Wagener G.; Schmidt-Ott K.M.; Tatonetti N.; Tempst P.; Oliver J.A.; Guarnieri P.; Barasch J.
Unique transcriptional programs identify subtypes of AKI
Journal of the American Society of Nephrology 28 (6): 1729-1740 (2017-06)



Kammertoens T.; Friese C.; Arina A.; Idel C.; Briesemeister D.; Rothe M.; Ivanov A.; Szymborska A.; Patone G.; Kunz S.; Sommermeyer D.; Engels B.; Leisegang M.; Textor A.; Fehling H.J.; Fruttiger M.; Lohoff M.; Herrmann A.; Yu H.; Weichselbaum R.; Uckert W.; Huebner N.; Gerhardt H.; Beule D.; Schreiber H.; Blankenstein T.
Tumour ischaemia by interferon-{gamma} resembles physiological blood vessel regression
Nature 545 (7652): 98-102 (2017-05-04)



Haase N.; Rueder C.; Haase H.; Kamann S.; Kouno M.; Morano I.; Dechend R.; Zohlnhoefer D.; Haase T.
Protective function of ahnak1 in vascular healing after wire injury
Journal of Vascular Research 54 (3): 131-142 (2017-05)



Matyash M.; Zabiegalov O.; Wendt S.; Matyash V.; Kettenmann H.
The adenosine generating enzymes CD39/CD73 control microglial processes ramification in the mouse brain
PLoS ONE 12 (4): e0175012 (2017-04-04)



Valenti G.; Quinn H.M.; Heynen G.J.J.E.; Lan L.; Holland J.D.; Vogel R.; Wulf-Goldenberg A.; Birchmeier W.
Cancer stem cells regulate cancer-associated fibroblasts via activation of Hedgehog signaling in mammary gland tumors
Cancer Research 77 (8): 2134-2147 (2017-04)



Bernal Sierra Y.A.; Haseleu J.; Kozlenkov A.; Begay V.; Lewin G.R.
Genetic tracing of Cav3.2 T-type calcium channel expression in the peripheral nervous system
Frontiers in Molecular Neuroscience 10 (70): 70 (2017-03-15)



Pahle J.; Menzel L.; Niesler N.; Kobelt D.; Aumann J.; Rivera M.; Walther W.
Rapid eradication of colon carcinoma by Clostridium perfringens Enterotoxin suicidal gene therapy
BMC Cancer 17 (1): 129 (2017-02-13)



2016

Eccles R.L.; Czajkowski M.T.; Barth C.; Mueller P.M.; McShane E.; Grunwald S.; Beaudette P.; Mecklenburg N.; Volkmer R.; Zuehlke K.; Dittmar G.; Selbach M.; Hammes A.; Daumke O.; Klussmann E.; Urbe S.; Rocks O.
Bimodal antagonism of PKA signalling by ARHGAP36
Nature Communications 7: 12963 (2016-10-07)



Jin S.; Kedia N.; Illes-Toth E.; Haralampiev I.; Prisner S.; Herrmann A.; Wanker E.E.; Bieschke J.
Amyloid-{beta}(1-42) aggregation initiates its cellular uptake and cytotoxicity
Journal of Biological Chemistry 291 (37): 19590-19606 (2016-09-09)



Seelk S.; Adrian-Kalchhauser I.; Hargitai B.; Hajduskova M.; Gutnik S.; Tursun B.; Ciosk R.
Increasing Notch signaling antagonizes PRC2-mediated silencing to promote reprograming of germ cells into neurons
eLife 5: e15477 (2016-09-07)



Wasinski F.; Estrela G.R.; Arakaki A.M.; Bader M.; Alenina N.; Klempin F.; Araujo R.C.
Maternal forced swimming reduces cell proliferation in the postnatal dentate gyrus of mouse offspring
Frontiers in Neuroscience 10: 402 (2016-08-29)



Becker M.S.; Mueller P.M.; Bajorat J.; Schroeder A.; Giaisi M.; Amin E.; Ahmadian M.R.; Rocks O.; Koehler R.; Krammer P.H.; Li-Weber M.
The anticancer phytochemical rocaglamide inhibits Rho GTPase activity and cancer cell migration
Oncotarget 7 (32): 51908-51921 (2016-08-09)



Magarin M.; Pohl T.; Lill A.; Schulz H.; Blaschke F.; Heuser A.; Thierfelder L.; Donath S.; Drenckhahn J.D.
Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress
Journal of Molecular and Cellular Cardiology 97: 1-14 (2016-08)



Ku M.C.; Edes I.; Bendix I.; Pohlmann A.; Waiczies H.; Prozorovski T.; Guenter M.; Martin C.; Pages G.; Wolf S.A.; Kettenmann H.; Uckert W.; Niendorf T.; Waiczies S.
ERK1 as a therapeutic target for dendritic cell vaccination against high-grade gliomas
Molecular Cancer Therapeutics 15 (8): 1975-1987 (2016-08)



Lisewski U.; Koehncke C.; Wilck N.; Buschmeyer B.; Pieske B.; Roepke T.K.
Increased aldosterone-dependent Kv1.5 recycling predisposes to pacing-induced atrial fibrillation in Kcne3-/- mice
FASEB Journal 30 (7): 2476-2489 (2016-07)



Uhlemann R.; Gertz K.; Boehmerle W.; Schwarz T.; Nolte C.; Freyer D.; Kettenmann H.; Endres M.; Kronenberg G.
Actin dynamics shape microglia effector functions
Brain Structure & Function 221 (5): 2717-2734 (2016-06)



Wogram E.; Wendt S.; Matyash M.; Pivneva T.; Draguhn A.; Kettenmann H.
Satellite microglia display spontaneous electrical activity uncorrelated with activity of the attached neuron
European Journal of Neuroscience 43 (11): 1523-1534 (2016-06)



Moehle L.; Mattei D.; Heimesaat M.M.; Bereswill S.; Fischer A.; Alutis M.; French T.; Hambardzumyan D.; Matzinger P.; Dunay I.R.; Wolf S.A.
Ly6C(hi) monocytes provide a link between antibiotic-induced changes in gut microbiota and adult hippocampal neurogenesis
Cell Reports 15 (9): 1945-1956 (2016-05-31)



Caliskan G.; Mueller I.; Semtner M.; Winkelmann A.; Raza A.S.; Hollnagel J.O.; Roesler A.; Heinemann U.; Stork O.; Meier J.C.
Identification of parvalbumin interneurons as cellular substrate of fear memory persistence
Cerebral Cortex 26 (5): 2325-2340 (2016-05)



Tomann P.; Paus R.; Millar S.E.; Scheidereit C.; Schmidt-Ullrich R.
LHX2 is a direct NF-{kappa}B target gene that promotes primary hair follicle placode down-growth
Development 143 (9): 1512-1522 (2016-05-01)



Cui H.; Schlesinger J.; Schoenhals S.; Toenjes M.; Dunkel I.; Meierhofer D.; Cano E.; Schulz K.; Berger M.F.; Haack T.; Abdelilah-Seyfried S.; Bulyk M.L.; Sauer S.; Sperling S.R.
Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA
Nucleic Acids Research 44 (6): 2538-2553 (2016-04-07)



Shcheslavskiy V.I.; Neubauer A.; Bukowiecki R.; Dinter F.; Becker W.
Combined fluorescence and phosphorescence lifetime imaging
Applied Physics Letters 108 (9): 091111 (2016-03-03)



Walentin K.; Hinze C.; Schmidt-Ott K.M.
The basal chorionic trophoblast cell layer: an emerging coordinator of placenta development
BioEssays 38 (3): 254-265 (2016-03)



Schuster I.; Mahmoodzadeh S.; Dworatzek E.; Jaisser F.; Messaoudi S.; Morano I.; Regitz-Zagrosek V.
Cardiomyocyte-specific overexpression of estrogen receptor beta improves survival and cardiac function after myocardial infarction in female and male mice
Clinical Science 130 (5): 365-376 (2016-01-26)



2015

Aue A.; Hinze C.; Walentin K.; Ruffert J.; Yurtdas Y.; Werth M.; Chen W.; Rabien A.; Kilic E.; Schulzke J.D.; Schumann M.; Schmidt-Ott K.M.
A grainyhead-like 2/Ovo-like 2 pathway regulates renal epithelial barrier function and lumen expansion
Journal of the American Society of Nephrology 26 (11): 2704-2715 (2015-11)



Griemsmann S.; Hoeft S.P.; Bedner P.; Zhang J.; von Staden E.; Beinhauer A.; Degen J.; Dublin P.; Cope D.W.; Richter N.; Crunelli V.; Jabs R.; Willecke K.; Theis M.; Seifert G.; Kettenmann H.; Steinhaeuser C.
Characterization of panglial gap junction networks in the thalamus, neocortex, and hippocampus reveals a unique population of glial cells
Cerebral Cortex 25 (10): 3420-3433 (2015-10)



Fossati G.; Morini R.; Corradini I.; Antonucci F.; Trepte P.; Edry E.; Sharma V.; Papale A.; Pozzi D.; Defilippi P.; Meier J.C.; Brambilla R.; Turco E.; Rosenblum K.; Wanker E.E.; Ziv N.E.; Menna E.; Matteoli M.
Reduced SNAP-25 increases PSD-95 mobility and impairs spine morphogenesis
Cell Death and Differentiation 22 (9): 1425-1436 (2015-09)



Mosimann C.; Panakova D.; Werdich A.A.; Musso G.; Burger A.; Lawson K.L.; Carr L.A.; Nevis K.R.; Sabeh M.K; Zhou Y.; Davidson A.J.; DiBiase A.; Burns C.E.; Burns C.G.; MacRae C.A.; Zon L.I.
Chamber identity programs drive early functional partitioning of the heart
Nature Communications 6: 8146 (2015-08-26)



Tattikota S.G.; Rathjen T.; Hausser J.; Khedkar A.; Kabra U.D.; Pandey V.K.; Sury M.D.; Wessels H.H.; Mollet I.G.; Eliasson L.; Selbach M.; Zinzen R.P.; Zavolan M.; Kadener S.; Tschoep M.; Jastroch M.; Friedlaender M.R.; Poy M.N.
miR-184 regulates pancreatic {beta}-cell function according to glucose metabolism
Journal of Biological Chemistry 290 (33): 20284-20294 (2015-08-14)



Lan L.; Holland J.D.; Qi J.; Grosskopf S.; Rademann J.; Vogel R.; Gyoerffy B.; Wulf-Goldenberg A.; Birchmeier W.
Shp2 signaling suppresses senescence in PyMT-induced mammary gland cancer in mice
EMBO Journal 34 (11): 1493-1508 (2015-06-03)



Reinthaler E.M.; Dejanovic B.; Lal D.; Semtner M.; Merkler Y.; Reinhold A.; Pittrich D.A.; Hotzy C.; Feucht M.; Steinboeck H.; Gruber-Sedlmayr U.; Ronen G.; Neophytou B.; Geldner J.; Haberlandt E.; Muhle H.; Ikram M.A.; van Duijn CM.; Uitterlinden A.G.; Hofman A.; Altmueller J.; Kawalia A.; Toliat M.R.; Nuernberg P.; Lerche H.; Nothnagel M.; Thiele H.; Sander T.; Meier J.C.; Schwarz G.; Neubauer B.A.; Zimprich F.
Rare variants in GABA(A) receptor genes in Rolandic epilepsy and related syndromes
Annals of Neurology 77 (6): 972-986 (2015-06)



Liskovykh M.; Ponomartsev S.; Popova E.; Bader M.; Kouprina N.; Larionov V.; Alenina N.; Tomilin A.
Stable maintenance of de novo assembled human artificial chromosomes in embryonic stem cells and their differentiated progeny in mice
Cell Cycle 14 (8): 1268-1273 (2015-04-15)



Fishman V.S.; Shnayder T.A.; Orishchenko K.E.; Bader M.; Alenina N.; Serov O.L.
Cell divisions are not essential for the direct conversion of fibroblasts into neuronal cells
Cell Cycle 14 (8): 1188-1196 (2015-04-15)



Drenckhahn J.D.; Strasen J.; Heinecke K.; Langner P.; Yin K.V.; Skole F.; Hennig M.; Spallek B.; Fischer R.; Blaschke F.; Heuser A.; Cox T.C.; Black M.J.; Thierfelder L.
Impaired myocardial development resulting in neonatal cardiac hypoplasia alters postnatal growth and stress response in the heart
Cardiovascular Research 106 (1): 43-54 (2015-04-01)



Walentin K.; Hinze C.; Werth M.; Haase N.; Varma S.; Morell R.; Aue A.; Poetschke E.; Warburton D.; Qiu A.; Barasch J.; Purfuerst B.; Dieterich C.; Popova E.; Bader M.; Dechend R.; Staff A.C.; Yurtdas Z.Y.; Kilic E.; Schmidt-Ott K.M.
A Grhl2-dependent gene network controls trophoblast branching morphogenesis
Development 142 (6): 1125-1136 (2015-03-15)



Rosenberger K.; Dembny P.; Derkow K.; Engel O.; Krueger C.; Wolf S.A.; Kettenmann H.; Schott E.; Meisel A.; Lehnardt S.
Intrathecal heat shock protein 60 mediates neurodegeneration and demyelination in the CNS through a TLR4-and MyD88-dependent pathway
Molecular Neurodegeneration 10: 5 (2015-02-26)



Hanack C.; Moroni M.; Lima W.C.; Wende H.; Kirchner M.; Adelfinger L.; Schrenk-Siemens K.; Tappe-Theodor A.; Wetzel C.; Kuich P.H.; Gassmann M.; Roggenkamp D.; Bettler B.; Lewin G.R.; Selbach M.; Siemens J.
GABA blocks pathological but not acute TRPV1 pain signals
Cell 160 (4): 759-770 (2015-02-12)



Preissler J.; Grosche A.; Lede V.; Le Duc D.; Kruegel K.; Matyash V.; Szulzewsky F.; Kallendrusch S.; Immig K.; Kettenmann H.; Bechmann I.; Schoeneberg T.; Schulz A.
Altered microglial phagocytosis in GPR34-deficient mice
Glia 63 (2): 206-215 (2015-02)



Hu F.; a Dzaye O.D.; Hahn A.; Yu Y.; Scavetta R.J.; Dittmar G.; Kaczmarek A.K.; Dunning K.R.; Ricciardelli C.; Rinnenthal J.L.; Heppner F.L.; Lehnardt S.; Synowitz M.; Wolf S.A.; Kettenmann H.
Glioma-derived versican promotes tumor expansion via glioma-associated microglial/macrophages Toll-like receptor 2 signaling
Neuro-Oncology 17 (2): 200-210 (2015-02)



Renz M.; Otten C.; Faurobert E.; Rudolph F.; Zhu Y.; Boulday G.; Duchene J.; Mickoleit M.; Dietrich A.C.; Ramspacher C.; Steed E.; Manet-Dupe S.; Benz A.; Hassel D.; Vermot J.; Huisken J.; Tournier-Lasserve E.; Felbor U.; Sure U.; Albiges-Rizo C.; Abdelilah-Seyfried S.
Regulation of {beta}1 integrin-Klf2-mediated angiogenesis by CCM proteins
Developmental Cell 32 (2): 181-190 (2015-01-26)



Mlih M.; Host L.; Martin S.; Niederhoffer N.; Monassier L.; Terrand J.; Messaddeq N.; Radke M.; Gotthardt M.; Bruban V.; Kober F.; Bernard M.; Canet-Soulas E.; Abt-Jijon F.; Boucher P.; Matz R.L.
The Src Homology and Collagen A (ShcA) adaptor protein is required for the spatial organization of the costamere/Z-disk network during heart development
Journal of Biological Chemistry 290 (4): 2419-2430 (2015-01-23)



Lombardo V.A.; Otten C.; Abdelilah-Seyfried S.
Large-scale zebrafish embryonic heart dissection for transcriptional analysis
Journal of Visualized Experiments (95): (2015-01-12)



Sury M.D.; McShane E.; Hernandez-Miranda L.R.; Birchmeier C.; Selbach M.
Quantitative proteomics reveals dynamic interaction of c-Jun N-terminal kinase (JNK) with RNA transport granule proteins splicing factor proline- and glutamine-rich (Sfpq) and non-POU domain-containing octamer-binding protein (Nono) during neuronal differentiation
Molecular & Cellular Proteomics 14 (1): 50-65 (2015-01-01)



2014

Wang J.; Xie G.; Singh M.; Ghanbarian A.T.; Rasko T.; Szvetnik A.; Cai H.; Besser D.; Prigione A.; Fuchs N.V.; Schumann G.G.; Chen W.; Lorincz M.C.; Ivics Z.; Hurst L.D.; Izsvak Z.
Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells
Nature 516 (7531): 405-409 (2014-12-18)



Stock K.; Garthe A.; de Almeida Sassi F.; Glass R.; Wolf S.A.; Kettenmann H.
The capsaicin receptor TRPV1 as a novel modulator of neural precursor cell proliferation
Stem Cells 32 (12): 3183-3195 (2014-12)



Hu F.; Ku M.C.; Markovic D.; a Dzaye O.D.; Lehnardt S.; Synowitz M.; Wolf S.A.; Kettenmann H.
Glioma-associated microglial MMP9 expression is upregulated by TLR2 signaling and sensitive to minocycline
International Journal of Cancer 135 (11): 2569-2578 (2014-12)



Richter N.; Wendt S.; Georgieva P.B.; Hambardzumyan D.; Nolte C.; Kettenmann H.
Glioma-associated microglia and macrophages/monocytes display distinct electrophysiological properties and do not communicate via gap junctions
Neuroscience Letters 583: 130-135 (2014-11-07)



Rharass T.; Lemcke H.; Lantow M.; Kuznetsov S.A.; Weiss D.G.; Panakova D.
Ca2+-mediated mitochondrial ROS metabolism augments Wnt/{beta}-catenin pathway activation to facilitate cell differentiation
Journal of Biological Chemistry 289 (40): 27937-27951 (2014-10-03)



Marg A.; Escobar H.; Gloy S.; Kufeld M.; Zacher J.; Spuler A.; Birchmeier C.; Izsvak Z.; Spuler S.
Human satellite cells have regenerative capacity and are genetically manipulable
Journal of Clinical Investigation 124 (10): 4257-4265 (2014-10-01)



Rehm A.; Gaetjen M.; Gerlach K.; Scholz F.; Mensen A.; Gloger M.; Heinig K.; Lamprecht B.; Mathas S.; Begay V.; Leutz A.; Lipp M.; Doerken B.; Hoepken U.E.
Dendritic cell-mediated survival signals in E{my}-Myc B-cell lymphoma depend on the transcription factor C/EBP{beta}
Nature Communications 5: 5057 (2014-09-30)



Foerstera B.; a Dzaye O.D.; Winkelmann A.; Semtner M.; Benedetti B.; Markovic D.S.; Synowitz M.; Wend P.; Faehling M.; Junier M.P.; Glass R.; Kettenmann H.; Meier J.C.
Intracellular glycine receptor function facilitates glioma formation in vivo
Journal of Cell Science 127 (Pt 17): 3687-3698 (2014-09-01)



Dietrich A.C.; Lombardo V.A.; Veerkamp J.; Priller F.; Abdelilah-Seyfried S.
Blood flow and Bmp signaling control endocardial chamber morphogenesis
Developmental Cell 30 (4): 367-377 (2014-08-25)



Kur E.; Mecklenburg N.; Cabrera R.M.; Willnow T.E.; Hammes A.
LRP2 mediates folate uptake in the developing neural tube
Journal of Cell Science 127 (Pt 10): 2261-2268 (2014-05-15)



Mattei D.; Djodari-Irani A.; Hadar R.; Pelz A.; de Cossio L.F.; Goetz T.; Matyash M.; Kettenmann H.; Winter C.; Wolf S.A.
Minocycline rescues decrease in neurogenesis, increase in microglia cytokines and deficits in sensorimotor gating in an animal model of schizophrenia
Brain Behavior and Immunity 38: 175-184 (2014-05)



Kobelt D.; Aumann J.; Schmidt M.; Wittig B.; Fichtner I.; Behrens D.; Lemm M.; Freundt G.; Schlag P.M.; Walther W.
Preclinical study on combined chemo- and nonviral gene therapy for sensitization of melanoma using a human TNF-alpha expressing MIDGE DNA vector
Molecular Oncology 8 (3): 609-619 (2014-05)



Schmitz T.; Krabbe G.; Weikert G.; Scheuer T.; Matheus F.; Wang Y.; Mueller S.; Kettenmann H.; Matyash V.; Buehrer C.; Endesfelder S.
Minocycline protects the immature white matter against hyperoxia
Experimental Neurology 254: 153-165 (2014-04)



Langenfurth A.; Rinnenthal J.L.; Vinnakota K.; Prinz V.; Carlo A.S.; Stadelmann C.; Siffrin V.; Peaschke S.; Endres M.; Heppner F.; Glass R.; Wolf S.A.; Kettenmann H.
Membrane-type 1 metalloproteinase is upregulated in microglia/brain macrophages in neurodegenerative and neuroinflammatory diseases
Journal of Neuroscience Research 92 (3): 275-286 (2014-03)



Kozlenkov A.; Lapatsina L.; Lewin G.R.; Smith E.S.J.
Subunit-specific inhibition of acid sensing ion channels by stomatin-like protein 1
Journal of Physiology 592 (Pt 4): 557-569 (2014-02-15)



Caglayan S.; Takagi-Niidome S.; Liao F.; Carlo A.S.; Schmidt V.; Burgert T.; Kitago Y.; Fuechtbauer E.M.; Fuechtbauer A.; Holtzman D.M.; Takagi J.; Willnow T.E.
Lysosomal sorting of amyloid-{beta} by the SORLA receptor is impaired by a familial Alzheimer's disease mutation
Science Translational Medicine 6 (223): 223ra20 (2014-02-12)



Winkelmann A.; Maggio N.; Eller J.; Caliskan G.; Semtner M.; Haeussler U.; Juettner R.; Dugladze T.; Smolinsky B.; Kowalczyk S.; Chronowska E.; Schwarz G.; Rathjen F.G.; Rechavi G.; Haas C.A.; Kulik A.; Gloveli T.; Heinemann U.; Meier J.C.
Changes in neural network homeostasis trigger neuropsychiatric symptoms
Journal of Clinical Investigation 124 (2): 696-711 (2014-02-03)



Ter-Avetisyan G.; Rathjen F.G.; Schmidt H.
Bifurcation of axons from cranial sensory neurons is disabled in the absence of Npr2-induced cGMP signaling
Journal of Neuroscience 34 (3): 737-747 (2014-01-15)



Tattikota S.G.; Rathjen T.; McAnulty S.J.; Wessels H.H.; Akerman I.; van de Bunt M.; Hausser J.; Esguerra J.L.S.; Musahl A.; Pandey A.K.; You X.; Chen W.; Herrera P.L.; Johnson P.R.; O'Carroll D.; Eliasson L.; Zavolan M.; Gloyn A.L.; Ferrer J.; Shalom-Feuerstein R.; Aberdam D.; Poy M.N.
Argonaute2 mediates compensatory expansion of the pancreatic {beta} cell
Cell Metabolism 19 (1): 122-134 (2014-01-07)



2013

Holland J.D.; Gyoerffy B.; Vogel R.; Eckert K.; Valenti G.; Fang L.; Lohneis P.; Elezkurtaj S.; Ziebold U.; Birchmeier W.
Combined Wnt/{beta}-catenin, met, and CXCL12/CXCR4 signals characterize basal breast cancer and predict disease outcome
Cell Reports 5 (5): 1214-1227 (2013-12-12)



Burgert T.; Schmidt V.; Caglayan S.; Lin F.; Fuechtbauer A.; Fuechtbauer E.M.; Nykjaer A.; Carlo A.S.; Willnow T.E.
SORLA-dependent and -independent functions for PACS1 in control of amyloidogenic processes
Molecular and Cellular Biology 33 (21): 4308-4320 (2013-11)



Vinnakota K.; Hu F.; Ku M.C.; Georgieva P.B.; Szulzewsky F.; Pohlmann A.; Waiczies S.; Waiczies H.; Niendorf T.; Lehnardt S.; Hanisch U.K.; Synowitz M.; Markovic D.S.; Wolf S.A.; Glass R.; Kettenmann H.
Toll-like receptor 2 mediates microglia/brain macrophage MT1-MMP expression and glioma expansion
Neuro-Oncology 15 (11): 1457-1468 (2013-11)



Goerlich A.; Antolin-Fontes B.; Ables J.L.; Frahm S.; Slimak M.A.; Dougherty J.D.; Ibanez-Tallon I.
Reexposure to nicotine during withdrawal increases the pacemaking activity of cholinergic habenular neurons
Proceedings of the National Academy of Sciences of the United States of America 110 (42): 17077-17082 (2013-10-15)



Carlo A.S.
Sortilin, a novel APOE receptor implicated in Alzheimer disease
Prion 7 (5): 378-382 (2013-09)



Jiang Q.; Lagos-Quintana M.; Liu D.; Shi Y.; Helker C.; Herzog W.; le Noble F.
miR-30a regulates endothelial tip cell formation and arteriolar branching
Hypertension 62 (3): 592-598 (2013-09)



Rohe M.; Hartl D.; Fjorback A.N.; Klose J.; Willnow T.E.
SORLA-mediated trafficking of TrkB enhances the response of neurons to BDNF
PLoS ONE 8 (8): e72164 (2013-08-19)



Arndt A.K.; Schaefer S.; Drenckhahn J.D.; Sabeh M.K.; Plovie E.R.; Caliebe A.; Klopocki E.; Musso G.; Werdich A.A.; Kalwa H.; Heinig M.; Padera R.F.; Wassilew K.; Bluhm J.; Harnack C.; Martitz J.; Barton P.J.; Greutmann M.; Berger F.; Huebner N.; Siebert R.; Kramer H.H.; Cook S.A.; Macrae C.A.; Klaassen S.
Fine mapping of the 1p36 deletion syndrome identifies mutation of PRDM16 as a cause of cardiomyopathy
American Journal of Human Genetics 93 (1): 67-77 (2013-07-11)



Bulavina L.; Szulzewsky F.; Rocha A.; Krabbe G.; Robson S.C.; Matyash V.; Kettenmann H.
NTPDase1 activity attenuates microglial phagocytosis
Purinergic Signalling 9 (2): 199-205 (2013-06)



Klempin F.; Beis D.; Mosienko V.; Kempermann G.; Bader M.; Alenina N.
Serotonin is required for exercise-induced adult hippocampal neurogenesis
Journal of Neuroscience 33 (19): 8270-8275 (2013-05-08)



Jerke U.; Rolle S.; Purfuerst B.; Luft F.C.; Nauseef W.M.; Kettritz R.
{beta}2 integrin-mediated cell-cell contact transfers active myeloperoxidase from neutrophils to endothelial cells
Journal of Biological Chemistry 288 (18): 12910-12919 (2013-05-03)



Krabbe G.; Halle A.; Matyash V.; Rinnenthal J.L.; Eom G.D.; Bernhardt U.; Miller K.R.; Prokop S.; Kettenmann H.; Heppner F.L.
Functional impairment of microglia coincides with beta-amyloid deposition in mice with Alzheimer-like pathology
PLoS ONE 8 (4): e60921 (2013-04-08)



Ku M.C.; Wolf S.A.; Respondek D.; Matyash V.; Pohlmann A.; Waiczies S.; Waiczies H.; Niendorf T.; Synowitz M.; Glass R.; Kettenmann H.
GDNF mediates glioblastoma-induced microglia attraction but not astrogliosis
Acta Neuropathologica 125 (4): 609-620 (2013-04)



Memczak S.; Jens M.; Elefsinioti A.; Torti F.; Krueger J.; Rybak A.; Maier L.; Mackowiak S.D.; Gregersen L.H.; Munschauer M.; Loewer A.; Ziebold U.; Landthaler M.; Kocks C.; le Noble F.; Rajewsky N.
Circular RNAs are a large class of animal RNAs with regulatory potency
Nature 495 (7441): 333-338 (2013-03-21)



Katter K.; Geurts A.M.; Hoffmann O.; Mates L.; Landa V.; Hiripi L.; Moreno C.; Lazar J.; Bashir S.; Zidek V.; Popova E.; Jerchow B.; Becker K.; Devaraj A.; Walter I.; Grzybowksi M.; Corbett M.; Filho A.R.; Hodges M.R.; Bader M.; Ivics Z.; Jacob H.J.; Pravenec M.; Bosze Z.; Ruelicke T.; Izsvak Z.
Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits
FASEB Journal 27 (3): 930-941 (2013-03)



Carlo A.S.; Gustafsen C.; Mastrobuoni G.; Nielsen M.S.; Burgert T.; Hartl D.; Rohe M.; Nykjaer A.; Herz J.; Heeren J.; Kempa S.; Petersen C.M.; Willnow T.E.
The pro-neurotrophin receptor sortilin is a major neuronal apolipoprotein E receptor for catabolism of amyloid-beta peptide in the brain
Journal of Neuroscience 33 (1): 358-370 (2013-01-02)



Sihn G.; Burckle C.; Rousselle A.; Reimer T.; Bader M.
(Pro)renin receptor: subcellular localizations and functions
Frontiers in Bioscience 5: 500-508 (2013-01-01)



Petzold K.M.; Naumann H.; Spagnoli F.M.
Rho signalling restriction by the RhoGAP Stard13 integrates growth and morphogenesis in the pancreas
Development 140 (1): 126-135 (2013-01-01)



Chuykin I.; Schulz H.; Guan K.; Bader M.
Activation of the PTHRP/adenylate cyclase pathway promotes differentiation of rat XEN cells into parietal endoderm, whereas Wnt/beta-catenin signaling promotes differentiation into visceral endoderm
Journal of Cell Science 126 (Pt 1): 128-138 (2013-01-01)



2012

Schoewel V.; Marg A.; Kunz S.; Overkamp T.; Siegert Carrazedo R.; Zacharias U.; Daniel P.T.; Spuler S.
Dysferlin-peptides reallocate mutated dysferlin thereby restoring function
PLoS ONE 7 (11): e49603 (2012-11-20)



Herda S.; Raczkowski F.; Mittruecker H.W.; Willimsky G.; Gerlach K.; Kuehl A.A.; Breiderhoff T.; Willnow T.E.; Doerken B.; Hoepken U.E.; Rehm A.
The sorting receptor sortilin exhibits a dual function in exocytic trafficking of interferon-{gamma} and granzyme A in T cells
Immunity 37 (5): 854-866 (2012-11-16)



Schulte L.; Schulz A.; Unland J.; Schulz H.; Hubner N.; Schmidt-Ott K.M.; Kreutz R.
MWF rats with spontaneous albuminuria inherit a reduced efficiency of nephron induction during early nephrogenesis in comparison to SHRs
Journal of Hypertension 30 (10): 2031-2038 (2012-10)



Marg A.; Schoewel V.; Timmel T.; Schulze A.; Shah C.; Daumke O.; Spuler S.
Sarcolemmal repair is a slow process and includes EHD2
Traffic 13 (9): 1286-1294 (2012-09)



Breiderhoff T.; Himmerkus N.; Stuiver M.; Mutig K.; Will C.; Meij I.C.; Bachmann S.; Bleich M.; Willnow T.E.; Mueller D.
Deletion of claudin-10 (Cldn10) in the thick ascending limb impairs paracellular sodium permeability and leads to hypermagnesemia and nephrocalcinosis
Proceedings of the National Academy of Sciences of the United States of America 109 (35): 14241-14246 (2012-08-28)



Kirchner F.; Schuetz A.; Boldt L.H.; Martens K.; Dittmar G.; Haverkamp W.; Thierfelder L.; Heinemann U.; Gerull B.
Molecular insights into arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 missense mutations
Circulation Cardiovascular Genetics 5 (4): 400-411 (2012-08-01)



Heller E.A.; Zhang W.; Selimi F.; Earnheart J.C.; Slimak M.A.; Santos-Torres J.; Ibanez-Tallon I.; Aoki C.; Chait B.T.; Heintz N.
The biochemical anatomy of cortical inhibitory synapses
PLoS ONE 7 (6): e39572 (2012-06-29)



Cibrian Uhalte E.; Kirchner M.; Hellwig N.; Allen J.J.; Donat S.; Shokat K.M.; Selbach M.; Abdelilah-Seyfried S.
In vivo conditions to identify prkci phosphorylation targets using the analog-sensitive kinase method in zebrafish
PLoS ONE 7 (6): e40000 (2012-06-29)



Lapatsina L.; Jira J.A.; Smith E.S.J.; Poole K.; Kozlenkov A.; Bilbao D.; Lewin G.R.; Heppenstall P.A.
Regulation of ASIC channels by a stomatin/STOML3 complex located in a mobile vesicle pool in sensory neurons
Open Biology 2 (6): 120096 (2012-06-27)



Tress O.; Maglione M.; May D.; Pivneva T.; Richter N.; Seyfarth J.; Binder S.; Zlomuzica A.; Seifert G.; Theis M.; Dere E.; Kettenmann H.; Willecke K.
Panglial gap junctional communication is essential for maintenance of myelin in the CNS
Journal of Neuroscience 32 (22): 7499-7518 (2012-05-30)



Guo W.; Schafer S.; Greaser M.L.; Radke M.H.; Liss M.; Govindarajan T.; Maatz H.; Schulz H.; Lincoln S.E.; Parrish A.M.; Dauksaite V.; Vakeel P.; Klaassen S.; Gerull B.; Thierfelder L.; Regitz-Zagrosek V.; Hacker T.A.; Saupe K.W.; Dec G.W.; Ellinor P.T.; MacRae C.A.; Spallek B.; Fischer R.; Perrot A.; Ozcelik C.; Saar K.; Hubner N.; Gotthardt M.
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing
Nature Medicine 18 (5): 766-773 (2012-05)



2011

Willecke R.; Heuberger J.; Grossmann K.; Michos O.; Schmidt-Ott K.; Walentin K.; Costantini F.; Birchmeier W.
The tyrosine phosphatase Shp2 acts downstream of GDNF/Ret in branching morphogenesis of the developing mouse kidney
Developmental Biology 360 (2): 310-307 (2011-12-15)



Liskovykh M.; Chuykin I.; Ranjan A.; Safina D.; Popova E.; Tolkunova E.; Mosienko V.; Minina J.M.; Zhdanova N.S.; Mullins J.J.; Bader M.; Alenina N.; Tomilin A.
Derivation, characterization, and stable transfection of induced pluripotent stem cells from Fischer344 rats
PLoS ONE 6 (11): e27345 (2011-11-04)



Foerster S.; Gretschel S.; Joens T.; Yashiro M.; Kemmner W.
THBS4, a novel stromal molecule of diffuse-type gastric adenocarcinomas, identified by transcriptome-wide expression profiling
Modern Pathology 24 (10): 1390-1403 (2011-10)



Laettig-Tuennemann G.; Prinz M.; Hoffmann D.; Behlke J.; Palm-Apergi C.; Morano I.; Herce H.D.; Cardoso M.C.
Backbone rigidity and static presentation of guanidinium groups increases cellular uptake of arginine-rich cell-penetrating peptides
Nature Communications 2: 453 (2011-08-30)



Rehm A.; Mensen A.; Schradi K.; Gerlach K.; Wittstock S.; Winter S.; Buechner G.; Doerken B.; Lipp M.; Hoepken U.E.
Cooperative function of CCR7 and lymphotoxin in the formation of a lymphoma-permissive niche within murine secondary lymphoid organs
Blood 118 (4): 1020-1033 (2011-07-28)



Chiang L.Y.; Poole K.; Oliveira B.E.; Duarte N.; Bernal Sierra Y.A.; Bruckner-Tuderman L.; Koch M.; Hu J.; Lewin G.R.
Laminin-332 coordinates mechanotransduction and growth cone bifurcation in sensory neurons
Nature Neuroscience 14 (8): 993-1000 (2011-07-03)



Tress O.; Maglione M.; Zlomuzica A.; May D.; Dicke N.; Degen J.; Dere E.; Kettenmann H.; Hartmann D.; Willecke K.
Pathologic and phenotypic alterations in a mouse expressing a connexin47 missense mutation that causes pelizaeus-merzbacher-like disease in humans
PLoS Genetics 7 (7): e1002146 (2011-07)



Petzhold D.; Lossie J.; Keller S.; Werner S.; Haase H.; Morano I.
Human essential myosin light chain isoforms revealed distinct myosin binding, sarcomeric sorting, and inotropic activity
Cardiovascular Research 90 (3): 513-520 (2011-06-01)



da Silva Lopes K.; Pietas A.; Radke M.H.; Gotthardt M.
Titin visualization in real time reveals an unexpected level of mobility within and between sarcomeres
Journal of Cell Biology 193 (4): 785-798 (2011-05-16)



Klein C.; Mikutta J.; Krueger J.; Scholz K.; Brinkmann J.; Liu D.; Veerkamp J.; Siegel D.; Abdelilah-Seyfried S.; Le Noble F.
Neuron navigator 3a regulates liver organogenesis during zebrafish embryogenesis
Development 138 (10): 1935-1945 (2011-05-15)



Frahm S.; Slimak M.A.; Ferrarese L.; Santos-Torres J.; Antolin-Fontes B.; Auer S.; Filkin S.; Pons S.; Fontaine J.F.; Tsetlin V.; Maskos U.; Ibanez-Tallon I.
Aversion to nicotine is regulated by the balanced activity of beta4 and alpha5 nicotinic receptor subunits in the medial habenula
Neuron 70 (3): 522-535 (2011-05-12)



Krueger J.; Liu D.; Scholz K.; Zimmer A.; Shi Y.; Klein C.; Siekmann A.; Schulte-Merker S.; Cudmore M.; Ahmed A.; Le Noble F.
Flt1 acts as a negative regulator of tip cell formation and branching morphogenesis in the zebrafish embryo
Development 138 (10): 2111-2120 (2011-05)



2010

Foerstera B.; Belaidi A.A.; Juettner R.; Bernert C.; Tsokos M.; Lehmann T.N.; Horn P.; Dehnicke C.; Schwarz G.; Meier J.C.
Irregular RNA splicing curtails postsynaptic gephyrin in the cornu ammonis of patients with epilepsy
Brain 133 (Pt12): 3778-3794 (2010-12)



Kronenberg G.; Gertz K.; Cheung G.; Buffo A.; Kettenmann H.; Goetz M.; Endres M.
Modulation of fate determinants Olig2 and Pax6 in resident glia evokes spiking neuroblasts in a model of mild brain ischemia
Stroke 41 (12): 2944-2949 (2010-12)



Werth M.; Walentin K.; Aue A.; Schoenheit J.; Wuebken A.; Pode-Shakked N.; Vilianovitch L.; Erdmann B.; Dekel B.; Bader M.; Barasch J.; Rosenbauer F.; Luft F.C.; Schmidt-Ott K.M.
The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex
Development 137 (22): 3835-3845 (2010-11)



Hinz M.; Stilmann M.; Coel Arslan S.; Khanna K.K.; Dittmar G.; Scheidereit C.
A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-kappaB activation
Molecular Cell 40 (1): 63-74 (2010-10-08)



Marg A.; Haase H.; Neumann T.; Kouno M.; Morano I.
AHNAK1 and AHNAK2 are costameric proteins: AHNAK1 affects transverse skeletal muscle fiber stiffness
Biochemical and Biophysical Research Communications 401 (1): 143-148 (2010-10-08)



Wolf J.; Reimer T.A.; Schuck S.; Rueder C.; Gerlach K.; Mueller E.C.; Otto A.; Doerken B.; Rehm A.
Role of EBAG9 protein in coat protein complex I-dependent glycoprotein maturation and secretion processes in tumor cells
FASEB Journal 24 (10): 4000-4019 (2010-10)



Maglione M.; Tress O.; Haas B.; Karram K.; Trotter J.; Willecke K.; Kettenmann H.
Oligodendrocytes in mouse corpus callosum are coupled via gap junction channels formed by connexin47 and connexin32
Glia 58 (9): 1104-1117 (2010-07)



Gajera C.R.; Emich H.; Lioubinski O.; Christ A.; Beckervordersandforth-Bonk R.; Yoshikawa K.; Bachmann S.; Christensen E.I.; Goetz M.; Kempermann G.; Peterson A.S.; Willnow T.E.; Hammes A.
LRP2 in ependymal cells regulates BMP signaling in the adult neurogenic niche
Journal of Cell Science 123 (Pt 11): 1922-1930 (2010-06-01)



Reiche J.; Theilig F.; Rafiqi F.H.; Carlo A.S.; Militz D.; Mutig K.; Todiras M.; Christensen E.I.; Ellison D.H.; Bader M.; Nykjaer A.; Bachmann S.; Alessi D.; Willnow T.E.
SORLA/SORL1 functionally interacts with SPAK to control renal activation of Na+-K+-Cl- cotransporter 2
Molecular and Cellular Biology 30 (12): 3027-3037 (2010-06)



Stuerzebecher A.S.; Hu J.; Smith E.S.J.; Frahm S.; Santos-Torres J.; Kampfrath B.; Auer S.; Lewin G.R.; Ibanez-Tallon I.
An in vivo tethered toxin approach for the cell-autonomous inactivation of voltage-gated sodium channel currents in nociceptors
Journal of Physiology 588 (Pt 10): 1695-1707 (2010-05-15)



Chuykin I.; Lapidus I.; Popova E.; Vilianovich L.; Mosienko V.; Alenina N.; Binas B.; Chai G.; Bader M.; Krivokharchenko A.
Characterization of trophoblast and extraembryonic endoderm cell lineages derived from rat preimplantation embryos
PLoS ONE 5 (3): e9794 (2010-03-29)



Kronenberg G.; Gertz K.; Baldinger T.; Kirste I.; Eckart S.; Yildirim F.; Ji S.; Heuser I.; Schroeck H.; Hoertnagl H.; Sohr R.; Djoufack P.C.; Juettner R.; Glass R.; Przesdzing I.; Kumar J.; Freyer D.; Hellweg R.; Kettenmann H.; Fink K.B.; Endres M.
Impact of actin filament stabilization on adult hippocampal and olfactory bulb neurogenesis
Journal of Neuroscience 30 (9): 3419-3431 (2010-03-03)



Auer S.; Stuerzebecher A.S.; Juettner R.; Santos-Torres J.; Hanack C.; Frahm S.; Liehl B.; Ibanez-Tallon I.
Silencing neurotransmission with membrane-tethered toxins
Nature Methods 7 (3): 229-236 (2010-03)



2009

Schmidt H.; Stonkute A.; Juettner R.; Koesling D.; Friebe A.; Rathjen F.G.
C-type natriuretic peptide (CNP) is a bifurcation factor for sensory neurons
Proceedings of the National Academy of Sciences of the United States of America 106 (39): 16847-16852 (2009-09-29)



Eichler S.A.; Foerstera B.; Smolinsky B.; Juettner R.; Lehmann T.N.; Faehling M.; Schwarz G.; Legendre P.; Meier J.C.
Splice-specific roles of glycine receptor alpha3 in the hippocampus
European Journal of Neuroscience 30 (6): 1077-1091 (2009-09)



Seipold S.; Priller F.C.; Goldsmith P.; Harris W.A.; Baier H.; Abdelilah-Seyfried S.
Non-SMC condensin I complex proteins control chromosome segregation and survival of proliferating cells in the zebrafish neural retina
BMC Developmental Biology 9 (1): 40 (2009-07-08)