BMBF projects

National Genome Research Network (NGFN 2) Projects

 

Genome network cardiovascular diseases: Comparative genomics of left ventricular hypertrophy and dysfunction in hypertension

Genome network cardiovascular diseases: Functional genomics of cardiac damage in hypertension

Genome network cardiovascular diseases: Location Berlin MDC: Prevalence of Titin-mutations and identification of new disease genes in patients with familial dilative cardiomyopathy

Systematic-methodical platform "DNA", location MDC, Berlin"

Systematic-methodical platform "DNA": National genotyping platform

Systematic-methodical platform GEM: Location Berlin "Genomwide correlation analysis and association studies with 10K and 100K arrays"

Genome network neuro: Systematic gene identification und functional analysis for frequent neurologic diseases

Genome network neuro: Molecular genetic identification of activity scheduled gene configurations of genetically determined epilepsies

CancerNet: Organ Specificity of Colorectal Cancer Metastasis

Systematic-methodical platform "Protein": Verification and identification of protein-protein interactions and systematic analysis of target proteins via X-ray structure analysis, TP 7 - Structure determination

Systematic-methodical platform "Protein": Verification and identification of protein-protein interactions and systematic analysis of target proteins via X-ray structure analysis, TP 20 - Project management

Systematic-methodical platform "Protein": Verification and identification of protein-protein interactions and systematic analysis of target proteins via X-ray structure analysis, TP 8 Yeast two-hybrid protein interaction networks

Systematic-methodical platform "Protein", Location MDC Berlin: Verification and identification of protein-protein interactions and systematic analysis of target proteins via X-ray structure analysis, TP 1.1. Subcloning of full-length ORF's and cDNA-fragments into expression plasmids

Determination of genes underlying Williams-Beuren Syndrom by generation of an allelic series of mutations with the aid of novel transposon approaches, TP1

 

 

National Genome Research Network (NGFN-Plus) Projects

 

Network genetics of heart failure: TP3 Regulatory networks of susceptability genes for cardial hypertrophy and heart failure

Network neurodegeneration (NeuroNet): Data integration and generation of phenotype-protein-active agent networks

Network neurodegeneration (NeuroNet): Protein Interaction screening via quantitative mass spectroscopy

Network neurodegeneration (NeuroNet): Protein-protein interaction networks for neurodegenerative diseases

Network neurodegeneration (NeuroNet): Generation and systematic analysis of protein-protein interaction networks via Yeast-2-Hybrid quantitative proteomics

Network neurodegeneration (NeuroNet): Generation of Gene expression signatures for neurodegenerative disease processes

Network neuroblastoma: Transposon based mutagenesis screen in the mouse

Network leukemia: The role of the WNT-signal transduction pathway on the development of leukemia stem cells

Network Alzheimer: The physiological function of BACE1-is BACE1 a safe therapeutic target?

Systems biology of genetically determined diseases: Mutanome. Generation and systematical analysis of protein-protein interaction networks

Network Alzheimer: Identification and characterization of modulators of Alzheimer's disease pathogenesis

Network: Molecular cause for affective disorders and schizophrenia. MOODS (TP11)

Installation of the scientific platform "Interactom" for systematic protein interaction studies