Research

 

1. Molecular Physiology of Somatic Sensation

Somatic sensation includes all those sensations that we consciously feel after stimulation of the body, e.g. touch, warmth, cooling, or even limb movement. We experience these sensations as a direct result of the activation of sensory neurons that are located in the dorsal root ganglia (DRG).... read more

 

2. Neuronal nanodetection and micro-patterning, engineering sensory neurons for function

The mechanosensitive ion channels that are expressed by sensory can be measured using high-resolution electrophysiology techniques. We have recently shown that such ion channels in the membranes of cultured DRG neurons can be activated by stimuli in the nanometer range....read more

 

3.Touch, hearing and the development of mechanosensation

Hereditary deafness is a relatively common phenomenon and a large number of genes have been identified that when mutated lead to deafness in mouse and man....read more

 

4. Tuning pain sensitivity

Nociception is describes our ability to respond to potentially or actually damaging stimuli. An important aspect of the biology of nociception is that after injury people and animals become much more sensitive to sensory stimulation than before injury....read more

 

5. The Naked Mole Rat a pain free mammal?

The naked mole rat is an unusual subterranean rodent in many respects. It is the only known poikilothermic mammal (ie. cold blooded), it lives in colonies with an insect-like social structure, and it is also the longest-lived rodent species known (lifetimes in excess of 25 yrs)....read more